STRINGSTRING
Sros_0500 Sros_0500 Sros_0616 Sros_0616 gpmA gpmA serC serC Sros_1177 Sros_1177 Sros_1638 Sros_1638 Sros_1649 Sros_1649 thrB thrB glyA glyA Sros_1754 Sros_1754 gcvH gcvH gcvT gcvT Sros_1807 Sros_1807 Sros_1880 Sros_1880 Sros_2555 Sros_2555 Sros_2589 Sros_2589 Sros_2645 Sros_2645 Sros_2777 Sros_2777 trpB trpB trpA trpA Sros_3752 Sros_3752 Sros_3854 Sros_3854 Sros_3855 Sros_3855 Sros_3856 Sros_3856 Sros_3858 Sros_3858 Sros_3859 Sros_3859 Sros_3925 Sros_3925 gcvP gcvP Sros_4119 Sros_4119 Sros_4372 Sros_4372 trpB-2 trpB-2 trpA-2 trpA-2 Sros_5201 Sros_5201 Sros_5222 Sros_5222 Sros_5544 Sros_5544 Sros_5603 Sros_5603 Sros_6048 Sros_6048 glyA-2 glyA-2 Sros_7146 Sros_7146 Sros_7521 Sros_7521 Sros_7698 Sros_7698 Sros_7699 Sros_7699 Sros_8047 Sros_8047 Sros_8119 Sros_8119 Sros_8167 Sros_8167 Sros_8241 Sros_8241 Sros_8547 Sros_8547 Sros_8566 Sros_8566 Sros_8831 Sros_8831 tdh tdh kbl kbl Sros_8913 Sros_8913 Sros_9236 Sros_9236 Sros_9310 Sros_9310 Sros_9311 Sros_9311 Sros_9381 Sros_9381
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Sros_0500Phosphoserine phosphatase; KEGG: scl:sce0663 hypothetical protein. (407 aa)
Sros_0616KEGG: nwi:Nwi_1813 dihydrolipoamide dehydrogenase. (466 aa)
gpmABisphosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
serCPhosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa)
Sros_1177KEGG: scl:sce6892 hypothetical protein. (474 aa)
Sros_1638KEGG: gme:Gmet_1629 homoserine dehydrogenase. (430 aa)
Sros_1649L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (336 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
Sros_1754KEGG: mms:mma_3335 L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (362 aa)
Sros_1807KEGG: spe:Spro_3642 gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
Sros_1880KEGG: abb:ABBFA_002457 gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
Sros_2555KEGG: dvm:DvMF_0572 threonine aldolase. (352 aa)
Sros_2589KEGG: mlo:mlr3510 threonine dehydratase. (303 aa)
Sros_2645KEGG: mxa:MXAN_4219 alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase. (459 aa)
Sros_2777KEGG: pmy:Pmen_1439 glycerate kinase; Belongs to the glycerate kinase type-1 family. (421 aa)
trpBTryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa)
Sros_3752KEGG: bbt:BBta_0633 putative cysteine synthase (O- acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSase). (351 aa)
Sros_3854Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (546 aa)
Sros_3855KEGG: dimethylglycine dehydrogenase precursor; Belongs to the GcvT family. (808 aa)
Sros_3856KEGG: rso:RSc1101 sarcosine oxidase subunit beta. (408 aa)
Sros_3858KEGG: bmj:BMULJ_05011 sarcosine oxidase alpha subunit; Belongs to the GcvT family. (937 aa)
Sros_3859KEGG: bvi:Bcep1808_7299 sarcosine oxidase, gamma subunit. (190 aa)
Sros_3925KEGG: sil:SPO3529 serine hydroxymethyltransferase. (417 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (951 aa)
Sros_4119KEGG: aca:ACP_1470 threonine dehydratase catabolic. (319 aa)
Sros_4372KEGG: mrd:Mrad2831_1541 pyridoxal-5'-phosphate- dependent protein beta subunit. (392 aa)
trpB-2Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpA-2Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa)
Sros_5201Methylase involved in ubiquinone/menaquinone biosynthesis-like protein; KEGG: hypothetical protein. (283 aa)
Sros_5222KEGG: sal:Sala_0902 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
Sros_5544KEGG: sil:SPO2415 phytanoyl-CoA dioxygenase family protein. (298 aa)
Sros_5603KEGG: bar:GBAA2018 amine oxidase, flavin-containing. (492 aa)
Sros_6048Phosphatidylserine synthase-like protein; KEGG: bsu:BSU02270 phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (276 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
Sros_7146Choline dehydrogenase; KEGG: bur:Bcep18194_C6848 glucose-methanol-choline oxidoreductase. (514 aa)
Sros_7521KEGG: aba:Acid345_1381 aldehyde dehydrogenase (acceptor). (481 aa)
Sros_7698KEGG: vei:Veis_2458 glycine dehydrogenase subunit 2. (519 aa)
Sros_7699Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (443 aa)
Sros_8047KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
Sros_8119KEGG: rce:RC1_3921 amine oxidase, flavin-containing. (520 aa)
Sros_8167Cu2+-containing amine oxidase-like protein; KEGG: sus:Acid_0916 tyramine oxidase. (431 aa)
Sros_8241KEGG: acr:Acry_2572 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (346 aa)
Sros_8547KEGG: gme:Gmet_3072 threonine dehydratase. (402 aa)
Sros_8566KEGG: scl:sce0438 cystathionine beta-synthase. (456 aa)
Sros_8831KEGG: sal:Sala_1845 FAD dependent oxidoreductase. (402 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (390 aa)
Sros_8913KEGG: aca:ACP_3389 threonine synthase. (429 aa)
Sros_9236KEGG: cvi:CV_0803 5-aminolevulinate synthase. (400 aa)
Sros_9310KEGG: pca:Pcar_1903 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa)
Sros_9311Aspartate kinase; KEGG: dat:HRM2_35870 LysC; Belongs to the aspartokinase family. (424 aa)
Sros_9381KEGG: dvm:DvMF_0572 threonine aldolase. (352 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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