STRINGSTRING
Sros_0778 Sros_0778 coaA coaA acpS acpS panB panB Sros_2815 Sros_2815 coaE coaE Sros_3016 Sros_3016 Sros_3052 Sros_3052 ilvE ilvE Sros_6148 Sros_6148 Sros_6635 Sros_6635 Sros_6712 Sros_6712 Sros_6934 Sros_6934 Sros_7323 Sros_7323 ilvD ilvD Sros_7969 Sros_7969 coaD coaD Sros_8041 Sros_8041 ilvC ilvC Sros_8058 Sros_8058 Sros_8059 Sros_8059 Sros_8313 Sros_8313 coaX coaX panD panD panC panC
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Sros_0778KEGG: scl:sce5007 putative aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family. (474 aa)
coaAKEGG: mxa:MXAN_2325 pantothenate kinase. (310 aa)
acpSHolo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (114 aa)
panB3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (281 aa)
Sros_2815Phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (413 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa)
Sros_3016Phosphopantetheinyl transferase-like protein; KEGG: mes:Meso_2583 4'-phosphopantetheinyl transferase. (226 aa)
Sros_3052KEGG: vei:Veis_4212 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (584 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (302 aa)
Sros_6148KEGG: sde:Sde_3057 branched chain amino acid aminotransferase. (276 aa)
Sros_6635Hydantoinase; KEGG: bav:BAV0626 hydantoinase. (470 aa)
Sros_6712KEGG: swi:Swit_2088 aldehyde dehydrogenase (acceptor). (479 aa)
Sros_6934KEGG: bar:GBAA2375 4'-phosphopantetheinyl transferase, putative; Belongs to the P-Pant transferase superfamily. (253 aa)
Sros_7323KEGG: bxe:Bxe_A1944 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa)
ilvDKEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (612 aa)
Sros_7969KEGG: bur:Bcep18194_B1170 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)
Sros_8041KEGG: nar:Saro_2671 branched-chain amino acid aminotransferase. (364 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa)
Sros_8058KEGG: gur:Gura_3719 acetolactate synthase 3 regulatory subunit. (174 aa)
Sros_8059KEGG: ade:Adeh_1978 acetolactate synthase, large subunit. (578 aa)
Sros_8313KEGG: scl:sce8127 putative acetolactate synthase; Belongs to the TPP enzyme family. (550 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (142 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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