STRINGSTRING
nth nth Sros_1317 Sros_1317 ung ung Sros_2177 Sros_2177 nfo nfo polA polA ligA ligA Sros_6069 Sros_6069 Sros_6245 Sros_6245 Sros_6678 Sros_6678 Sros_6749 Sros_6749 lig lig mutM mutM ligA-2 ligA-2 Sros_8424 Sros_8424 Sros_8576 Sros_8576 Sros_9146 Sros_9146 Sros_9360 Sros_9360
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (241 aa)
Sros_1317KEGG: rru:Rru_A3357 transcriptional regulator Ada / DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine-- protein-cysteine S-methyltransferase. (467 aa)
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa)
Sros_2177KEGG: afw:Anae109_1725 DNA-(apurinic or apyrimidinic site) lyase. (263 aa)
nfoDeoxyribonuclease IV (phage-T(4)-induced); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (283 aa)
polADNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (901 aa)
ligADNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (696 aa)
Sros_6069KEGG: bmu:Bmul_0540 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (228 aa)
Sros_6245DNA-(apurinic or apyrimidinic site) lyase; KEGG: aca:ACP_0800 putative formamidopyrimidine-DNA glycosylase. (269 aa)
Sros_6678DNA polymerase I - 3'-5' exonuclease and polymerase domains-like protein; KEGG: met:M446_0678 DNA polymerase I. (531 aa)
Sros_6749G:T/U mismatch-specific DNA glycosylase-like protein; KEGG: scl:sce5098 G/U mismatch-specific DNA glycosylase. (208 aa)
ligATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (508 aa)
mutMDNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (288 aa)
ligA-2DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (726 aa)
Sros_8424KEGG: azc:AZC_0402 DNA-3-methyladenine glycosylase I. (185 aa)
Sros_8576KEGG: acp:A2cp1_3772 uracil-DNA glycosylase superfamily. (266 aa)
Sros_9146A/G-specific DNA glycosylase-like protein; KEGG: msl:Msil_1600 A/G-specific adenine glycosylase. (291 aa)
Sros_9360KEGG: sfu:Sfum_0659 apurinic endonuclease Apn1. (252 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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