STRINGSTRING
Sthe_0229 Sthe_0229 Sthe_0230 Sthe_0230 Sthe_1933 Sthe_1933 Sthe_1934 Sthe_1934 pdhA pdhA Sthe_2121 Sthe_2121 Sthe_3132 Sthe_3132 Sthe_3133 Sthe_3133 Sthe_3224 Sthe_3224 Sthe_3225 Sthe_3225 Sthe_3226 Sthe_3226 Sthe_3227 Sthe_3227 Sthe_3475 Sthe_3475 Sthe_3476 Sthe_3476 Sthe_3477 Sthe_3477 Sthe_3491 Sthe_3491 Sthe_3492 Sthe_3492 Sthe_3493 Sthe_3493
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_0229PFAM: Transketolase central region; Transketolase domain protein; KEGG: sso:SSO1526 pyruvate dehydrogenase beta subunit (lipoamide). (326 aa)
Sthe_0230Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; KEGG: tte:TTE0186 thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit. (324 aa)
Sthe_1933PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: rrs:RoseRS_1726 dihydrolipoyllysine-residue succinyltransferase. (443 aa)
Sthe_1934Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (336 aa)
Sthe_2121Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (801 aa)
Sthe_3132Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; KEGG: azo:azo3867 acetoin dehydrogenase, alpha subunit. (345 aa)
Sthe_3133PFAM: Transketolase central region; Transketolase domain protein; KEGG: azo:azo3868 acetoin dehydrogenase, beta subunit. (341 aa)
Sthe_3224PFAM: dehydrogenase E1 component; KEGG: pfl:PFL_2170 acetoin dehydrogenase E1 component, alpha subunit. (333 aa)
Sthe_3225PFAM: Transketolase central region; Transketolase domain protein; KEGG: bcj:BCAL1910 acetoin:2,6- dichlorophenolindophenol oxidoreductase beta subunit. (342 aa)
Sthe_3226PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: pag:PLES_07751 branched-chain alpha-keto acid dehydrogenase subunit E2. (376 aa)
Sthe_3227ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (346 aa)
Sthe_3475PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: rpb:RPB_0277 dihydrolipoamide acetyltransferase. (467 aa)
Sthe_3476PFAM: Transketolase central region; Transketolase domain protein; KEGG: ade:Adeh_1826 branched-chain alpha-keto acid dehydrogenase E1 component. (328 aa)
Sthe_3477PFAM: dehydrogenase E1 component; KEGG: ade:Adeh_1827 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). (340 aa)
Sthe_3491PFAM: glycosyl transferase group 1; KEGG: cja:CJA_0616 glycosyl transferase, putative, gt4J. (390 aa)
Sthe_3492PFAM: biotin/lipoate A/B protein ligase; KEGG: bbr:BB2891 putative lipoate-protein ligase A. (260 aa)
Sthe_3493KEGG: oan:Oant_2218 biotin/lipoate A/B protein ligase. (91 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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