STRINGSTRING
dnaG dnaG Sthe_0440 Sthe_0440 sigA sigA sigA-2 sigA-2 Sthe_1216 Sthe_1216 Sthe_1217 Sthe_1217 murJ murJ lepA lepA Sthe_1220 Sthe_1220 Sthe_1849 Sthe_1849 Sthe_2015 Sthe_2015 Sthe_2016 Sthe_2016 Sthe_3130 Sthe_3130 Sthe_3131 Sthe_3131
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (615 aa)
Sthe_0440Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: nis:NIS_0956 MerR family transcriptional regulator. (119 aa)
sigARNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (538 aa)
sigA-2RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (390 aa)
Sthe_1216PFAM: Cupin 2 conserved barrel domain protein; KEGG: rpc:RPC_2626 cupin 2, conserved barrel. (118 aa)
Sthe_1217Hypothetical protein. (95 aa)
murJIntegral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (549 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (610 aa)
Sthe_1220TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rrs:RoseRS_1334 MazG family protein. (466 aa)
Sthe_1849RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (341 aa)
Sthe_2015PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_1154 ThiJ/PfpI domain-containing protein. (187 aa)
Sthe_2016TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: rxy:Rxyl_3199 secretion chaperone CsaA. (109 aa)
Sthe_3130RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (359 aa)
Sthe_3131PFAM: Putitive phosphate transport regulator; KEGG: gur:Gura_4136 hypothetical protein. (208 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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