STRINGSTRING
murG murG Sthe_1162 Sthe_1162 Sthe_1163 Sthe_1163 murA murA murB murB ftsZ ftsZ Sthe_1988 Sthe_1988 Sthe_1989 Sthe_1989 ddl ddl murC murC Sthe_1992 Sthe_1992 murD murD mraY mraY murF murF Sthe_1996 Sthe_1996 Sthe_1997 Sthe_1997 rsmH rsmH mraZ mraZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (384 aa)
Sthe_1162PFAM: cell cycle protein; KEGG: rca:Rcas_0578 cell cycle protein; Belongs to the SEDS family. (436 aa)
Sthe_1163Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; KEGG: cau:Caur_1804 peptidoglycan glycosyltransferase. (553 aa)
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (424 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (321 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (369 aa)
Sthe_1988KEGG: sth:STH1218 cell division protein FtsA. (391 aa)
Sthe_1989Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. (256 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (375 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (473 aa)
Sthe_1992TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: hau:Haur_3512 cell division protein FtsW; Belongs to the SEDS family. (464 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (481 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (346 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (463 aa)
Sthe_1996Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cau:Caur_0761 peptidoglycan glycosyltransferase. (582 aa)
Sthe_1997KEGG: hau:Haur_3518 hypothetical protein. (160 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (326 aa)
mraZTIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: rca:Rcas_1104 MraZ protein; Belongs to the MraZ family. (142 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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