STRINGSTRING
Sthe_1214 Sthe_1214 dinG dinG Sthe_0855 Sthe_0855 Sthe_0659 Sthe_0659 Sthe_0314 Sthe_0314 Sthe_0227 Sthe_0227 Sthe_1312 Sthe_1312 polA polA dnaX dnaX dinB dinB Sthe_2045 Sthe_2045 Sthe_1301 Sthe_1301
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_1214TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: cau:Caur_2419 DNA polymerase III, delta subunit. (340 aa)
dinGExonuclease RNase T and DNA polymerase III; 3'-5' exonuclease. (966 aa)
Sthe_0855KEGG: afe:Lferr_2703 PHP domain protein. (169 aa)
Sthe_0659TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: rrs:RoseRS_3588 DNA polymerase III, delta prime subunit. (346 aa)
Sthe_0314TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: swo:Swol_1124 hypothetical protein. (301 aa)
Sthe_0227KEGG: msm:MSMEG_1633 DNA polymerase III, alpha subunit, putative; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1095 aa)
Sthe_1312DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (379 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (915 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (589 aa)
dinBDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (394 aa)
Sthe_2045DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: dau:Daud_0758 DNA-directed DNA polymerase. (397 aa)
Sthe_1301KEGG: det:DET1464 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. (1167 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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