STRINGSTRING
Sthe_2411 Sthe_2411 Sthe_0031 Sthe_0031 Sthe_0118 Sthe_0118 Sthe_0156 Sthe_0156 Sthe_0181 Sthe_0181 Sthe_0198 Sthe_0198 Sthe_0199 Sthe_0199 Sthe_0244 Sthe_0244 Sthe_0368 Sthe_0368 Sthe_0597 Sthe_0597 Sthe_0750 Sthe_0750 Sthe_0811 Sthe_0811 Sthe_0833 Sthe_0833 Sthe_0911 Sthe_0911 Sthe_1079 Sthe_1079 Sthe_1143 Sthe_1143 Sthe_1269 Sthe_1269 Sthe_1551 Sthe_1551 Sthe_1616 Sthe_1616 Sthe_1617 Sthe_1617 Sthe_1765 Sthe_1765 Sthe_1859 Sthe_1859 Sthe_1940 Sthe_1940 Sthe_2026 Sthe_2026 Sthe_2031 Sthe_2031 Sthe_2039 Sthe_2039 Sthe_2198 Sthe_2198 Sthe_2401 Sthe_2401 Sthe_2457 Sthe_2457 Sthe_2654 Sthe_2654 Sthe_2665 Sthe_2665 Sthe_2694 Sthe_2694 Sthe_2731 Sthe_2731 Sthe_2732 Sthe_2732 Sthe_2752 Sthe_2752 Sthe_3075 Sthe_3075 Sthe_3242 Sthe_3242 Sthe_3274 Sthe_3274 Sthe_3275 Sthe_3275 Sthe_3280 Sthe_3280 Sthe_3287 Sthe_3287 Sthe_3347 Sthe_3347 Sthe_3455 Sthe_3455
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_2411Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0428 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. (788 aa)
Sthe_0031PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mma:MM_1068 two-component response regulator. (133 aa)
Sthe_0118PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: rxy:Rxyl_0943 serine/threonine protein kinase. (343 aa)
Sthe_0156PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: sco:SCO1802 two-component system sensor kinase. (492 aa)
Sthe_0181Histidine kinase; KEGG: bcl:ABC0528 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (477 aa)
Sthe_0198Putative signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; SMART: GAF domain protein; KEGG: rca:Rcas_3064 GAF sensor signal transduction histidine kinase. (780 aa)
Sthe_0199PFAM: histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: cau:Caur_0656 histidine kinase dimerisation and phosphoacceptor region. (420 aa)
Sthe_0244Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: sth:STH2634 two-component sensor histidine kinase. (456 aa)
Sthe_0368KEGG: det:DET0136 sensory box sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein. (598 aa)
Sthe_0597Histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; KEGG: gvi:gll1661 similar to two-component sensor histidine kinase. (489 aa)
Sthe_0750Histidine kinase; KEGG: rrs:RoseRS_0613 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (464 aa)
Sthe_0811PFAM: histidine kinase dimerisation and phosphoacceptor region; KEGG: rca:Rcas_1122 histidine kinase. (362 aa)
Sthe_0833PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: hau:Haur_2960 serine/threonine protein kinase with PASTA sensor(s). (625 aa)
Sthe_0911Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: hau:Haur_0906 integral membrane sensor signal transduction histidine kinase. (543 aa)
Sthe_1079PFAM: ABC-1 domain protein; KEGG: cau:Caur_0631 hypothetical protein. (563 aa)
Sthe_1143Capsular exopolysaccharide family; KEGG: rrs:RoseRS_4270 non-specific protein-tyrosine kinase; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein. (544 aa)
Sthe_1269Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_0881 integral membrane sensor signal transduction histidine kinase. (567 aa)
Sthe_1551Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: rxy:Rxyl_0159 periplasmic sensor signal transduction histidine kinase. (437 aa)
Sthe_1616Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: rrs:RoseRS_0939 histidine kinase. (218 aa)
Sthe_1617KEGG: hypothetical protein. (139 aa)
Sthe_1765KEGG: ank:AnaeK_1722 hypothetical protein. (283 aa)
Sthe_1859Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (297 aa)
Sthe_1940Histidine kinase; KEGG: pth:PTH_0047 signal transduction protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (366 aa)
Sthe_2026Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: mta:Moth_1130 periplasmic sensor signal transduction histidine kinase. (493 aa)
Sthe_2031Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_1498 GAF sensor signal transduction histidine kinase. (383 aa)
Sthe_2039Multi-sensor signal transduction histidine kinase; KEGG: cau:Caur_1171 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein. (523 aa)
Sthe_2198Histidine kinase; KEGG: hau:Haur_0906 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (538 aa)
Sthe_2401Multi-sensor signal transduction histidine kinase; KEGG: ana:all5210 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; GAF domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (1448 aa)
Sthe_2457PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: acr:Acry_0713 osmosensitive K+ channel signal transduction histidine kinase. (424 aa)
Sthe_2654PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: azo:azo3774 putative serine/threonine protein kinase. (592 aa)
Sthe_2665Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0186 two-component histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein. (645 aa)
Sthe_2694Multi-sensor signal transduction histidine kinase; KEGG: scl:sce5443 protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (668 aa)
Sthe_2731PFAM: lipopolysaccharide biosynthesis protein; KEGG: dal:Dalk_0426 lipopolysaccharide biosynthesis protein. (227 aa)
Sthe_2732PFAM: lipopolysaccharide biosynthesis protein; KEGG: dat:HRM2_25570 GumC2. (234 aa)
Sthe_2752Capsular exopolysaccharide family; KEGG: eba:ebA6797 exopolysaccharide biosynthesis protein; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein. (557 aa)
Sthe_3075Multi-sensor signal transduction histidine kinase; KEGG: mxa:MXAN_7398 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAS domain containing protein. (936 aa)
Sthe_3242KEGG: afw:Anae109_4151 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein. (883 aa)
Sthe_3274Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0589 multi-sensor signal transduction histidine kinase. (398 aa)
Sthe_3275KEGG: similar to hedgehog protein. (297 aa)
Sthe_3280PFAM: PrkA AAA domain protein; PrkA serine kinase; SMART: PrkA AAA domain protein; KEGG: ade:Adeh_1230 putative serine protein kinase, PrkA. (645 aa)
Sthe_3287KEGG: ank:AnaeK_1718 hypothetical protein. (416 aa)
Sthe_3347KEGG: bph:Bphy_7756 PAS sensor protein; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein. (555 aa)
Sthe_3455Capsular exopolysaccharide family; KEGG: noc:Noc_1497 protein-tyrosine kinase; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein. (564 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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