STRINGSTRING
Sthe_3426 Sthe_3426 Sthe_3417 Sthe_3417 Sthe_3406 Sthe_3406 Sthe_3401 Sthe_3401 Sthe_3394 Sthe_3394 Sthe_3377 Sthe_3377 Sthe_3366 Sthe_3366 Sthe_3347 Sthe_3347 Sthe_3345 Sthe_3345 Sthe_3344 Sthe_3344 Sthe_3341 Sthe_3341 Sthe_3242 Sthe_3242 Sthe_3241 Sthe_3241 Sthe_3240 Sthe_3240 Sthe_3218 Sthe_3218 Sthe_3200 Sthe_3200 Sthe_3199 Sthe_3199 Sthe_3198 Sthe_3198 Sthe_3197 Sthe_3197 Sthe_3183 Sthe_3183 Sthe_3164 Sthe_3164 Sthe_3158 Sthe_3158 Sthe_3130 Sthe_3130 Sthe_3127 Sthe_3127 Sthe_3104 Sthe_3104 Sthe_3081 Sthe_3081 Sthe_3075 Sthe_3075 Sthe_3067 Sthe_3067 Sthe_3049 Sthe_3049 Sthe_3042 Sthe_3042 Sthe_3026 Sthe_3026 Sthe_3010 Sthe_3010 Sthe_2984 Sthe_2984 Sthe_2978 Sthe_2978 Sthe_2955 Sthe_2955 Sthe_2937 Sthe_2937 Sthe_2918 Sthe_2918 Sthe_2881 Sthe_2881 Sthe_2880 Sthe_2880 Sthe_2869 Sthe_2869 Sthe_2848 Sthe_2848 Sthe_2833 Sthe_2833 Sthe_2796 Sthe_2796 Sthe_2783 Sthe_2783 Sthe_2735 Sthe_2735 Sthe_2725 Sthe_2725 Sthe_2695 Sthe_2695 Sthe_2694 Sthe_2694 Sthe_2675 Sthe_2675 Sthe_2666 Sthe_2666 Sthe_2665 Sthe_2665 Sthe_2664 Sthe_2664 Sthe_2661 Sthe_2661 Sthe_2631 Sthe_2631 Sthe_2601 Sthe_2601 Sthe_2566 Sthe_2566 Sthe_2537 Sthe_2537 Sthe_2526 Sthe_2526 Sthe_2457 Sthe_2457 Sthe_2441 Sthe_2441 Sthe_2411 Sthe_2411 Sthe_2401 Sthe_2401 Sthe_2390 Sthe_2390 Sthe_2386 Sthe_2386 Sthe_2385 Sthe_2385 Sthe_2376 Sthe_2376 Sthe_2353 Sthe_2353 Sthe_2348 Sthe_2348 Sthe_2346 Sthe_2346 Sthe_2338 Sthe_2338 Sthe_2322 Sthe_2322 Sthe_2307 Sthe_2307 Sthe_2252 Sthe_2252 Sthe_2246 Sthe_2246 Sthe_2244 Sthe_2244 Sthe_2230 Sthe_2230 Sthe_2225 Sthe_2225 Sthe_2198 Sthe_2198 Sthe_2197 Sthe_2197 Sthe_2190 Sthe_2190 Sthe_2189 Sthe_2189 Sthe_2174 Sthe_2174 Sthe_2172 Sthe_2172 rex rex Sthe_2135 Sthe_2135 Sthe_2129 Sthe_2129 Sthe_2119 Sthe_2119 Sthe_2104 Sthe_2104 Sthe_2095 Sthe_2095 Sthe_2084 Sthe_2084 Sthe_2073 Sthe_2073 Sthe_2043 Sthe_2043 Sthe_2039 Sthe_2039 Sthe_2031 Sthe_2031 Sthe_2027 Sthe_2027 Sthe_2026 Sthe_2026 Sthe_2015 Sthe_2015 minC minC minE minE mraZ mraZ nrdR nrdR Sthe_1974 Sthe_1974 Sthe_1941 Sthe_1941 Sthe_1940 Sthe_1940 prfA prfA Sthe_1898 Sthe_1898 Sthe_1890 Sthe_1890 Sthe_1862 Sthe_1862 Sthe_1849 Sthe_1849 Sthe_1845 Sthe_1845 Sthe_1819 Sthe_1819 Sthe_1815 Sthe_1815 Sthe_1761 Sthe_1761 Sthe_1755 Sthe_1755 Sthe_1746 Sthe_1746 tsf tsf lexA lexA mutS2 mutS2 mfd mfd Sthe_1677 Sthe_1677 Sthe_1658 Sthe_1658 Sthe_1646 Sthe_1646 Sthe_1617 Sthe_1617 Sthe_1616 Sthe_1616 Sthe_1615 Sthe_1615 tuf-2 tuf-2 nusG nusG rplA rplA Sthe_1603 Sthe_1603 dacA dacA Sthe_1568 Sthe_1568 Sthe_1567 Sthe_1567 Sthe_1565 Sthe_1565 Sthe_1552 Sthe_1552 Sthe_1551 Sthe_1551 Sthe_1546 Sthe_1546 Sthe_1521 Sthe_1521 Sthe_1487 Sthe_1487 Sthe_1465 Sthe_1465 hpf hpf Sthe_1437 Sthe_1437 recX recX Sthe_1396 Sthe_1396 Sthe_1380 Sthe_1380 Sthe_1375 Sthe_1375 Sthe_1372 Sthe_1372 Sthe_1367 Sthe_1367 Sthe_1366 Sthe_1366 Sthe_1270 Sthe_1270 Sthe_1269 Sthe_1269 infB infB nusA nusA Sthe_1242 Sthe_1242 Sthe_1241 Sthe_1241 Sthe_1229 Sthe_1229 lepA lepA sigA-2 sigA-2 Sthe_1184 Sthe_1184 infC infC Sthe_1168 Sthe_1168 Sthe_1146 Sthe_1146 Sthe_1145 Sthe_1145 Sthe_1115 Sthe_1115 greA-2 greA-2 infA-2 infA-2 infA infA tuf tuf fusA fusA Sthe_0984 Sthe_0984 Sthe_0911 Sthe_0911 Sthe_0910 Sthe_0910 Sthe_0867 Sthe_0867 Sthe_0841 Sthe_0841 Sthe_0816 Sthe_0816 Sthe_0811 Sthe_0811 efp efp Sthe_0762 Sthe_0762 Sthe_0751 Sthe_0751 Sthe_0750 Sthe_0750 sigA sigA prfB prfB hrcA hrcA selA selA Sthe_0681 Sthe_0681 Sthe_0675 Sthe_0675 Sthe_0649 Sthe_0649 Sthe_0648 Sthe_0648 Sthe_0628 Sthe_0628 Sthe_0609 Sthe_0609 Sthe_0608 Sthe_0608 Sthe_0597 Sthe_0597 Sthe_0596 Sthe_0596 Sthe_0589 Sthe_0589 Sthe_0569 Sthe_0569 Sthe_0564 Sthe_0564 fliW fliW csrA csrA Sthe_0518 Sthe_0518 Sthe_0470 Sthe_0470 Sthe_0469 Sthe_0469 Sthe_0459 Sthe_0459 Sthe_0444 Sthe_0444 Sthe_0440 Sthe_0440 Sthe_0432 Sthe_0432 Sthe_0400 Sthe_0400 Sthe_0397 Sthe_0397 nusB nusB Sthe_0369 Sthe_0369 Sthe_0368 Sthe_0368 Sthe_0362 Sthe_0362 Sthe_0353 Sthe_0353 Sthe_0315 Sthe_0315 Sthe_0285 Sthe_0285 Sthe_0269 Sthe_0269 Sthe_0265 Sthe_0265 greA greA Sthe_0244 Sthe_0244 Sthe_0243 Sthe_0243 Sthe_0238 Sthe_0238 Sthe_0235 Sthe_0235 Sthe_0200 Sthe_0200 Sthe_0199 Sthe_0199 Sthe_0198 Sthe_0198 Sthe_0182 Sthe_0182 Sthe_0181 Sthe_0181 Sthe_0156 Sthe_0156 Sthe_0155 Sthe_0155 Sthe_0148 Sthe_0148 Sthe_0135 Sthe_0135 Sthe_0121 Sthe_0121 Sthe_0120 Sthe_0120 Sthe_0119 Sthe_0119 Sthe_0107 Sthe_0107 Sthe_0094 Sthe_0094 Sthe_0075 Sthe_0075 Sthe_0050 Sthe_0050 Sthe_0039 Sthe_0039 Sthe_0031 Sthe_0031 Sthe_0027 Sthe_0027 Sthe_0005 Sthe_0005 dnaA dnaA Sthe_3340 Sthe_3340 Sthe_3333 Sthe_3333 Sthe_3327 Sthe_3327 Sthe_3323 Sthe_3323 Sthe_3316 Sthe_3316 Sthe_3286 Sthe_3286 Sthe_3284 Sthe_3284 Sthe_3274 Sthe_3274 Sthe_3273 Sthe_3273 Sthe_3271 Sthe_3271 Sthe_3268 Sthe_3268 Sthe_3502 Sthe_3502 Sthe_3494 Sthe_3494 Sthe_3478 Sthe_3478 Sthe_3462 Sthe_3462
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_3426Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR. (227 aa)
Sthe_3417Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (86 aa)
Sthe_3406KEGG: gur:Gura_1941 metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; metal dependent phophohydrolase; PFAM: GGDEF domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: GGDEF domain containing protein; metal- dependent phosphohydrolase HD region; GAF domain protein. (1113 aa)
Sthe_3401Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: smd:Smed_6276 CRP/FNR family transcriptional regulator. (252 aa)
Sthe_3394PFAM: regulatory protein LysR; KEGG: sfu:Sfum_1701 putative transcriptional regulator, ModE family. (136 aa)
Sthe_3377PFAM: regulatory protein TetR; KEGG: pfl:PFL_2927 TetR family transcriptional regulator. (192 aa)
Sthe_3366PFAM: regulatory protein TetR; KEGG: rhi:NGR_c29540 putative transcriptional regulator, TetR family. (226 aa)
Sthe_3347KEGG: bph:Bphy_7756 PAS sensor protein; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein. (555 aa)
Sthe_3345RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rso:RSc2361 RNA polymerase sigma-E factor sigma-24 homolog transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
Sthe_3344PFAM: Anti-sigma-K factor RskA; KEGG: aav:Aave_2584 hypothetical protein. (265 aa)
Sthe_3341SMART: AAA ATPase; KEGG: mpt:Mpe_A0763 ATP-dependent transcriptional regulator-like protein protein. (467 aa)
Sthe_3242KEGG: afw:Anae109_4151 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein. (883 aa)
Sthe_3241Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: xca:xccb100_2001 two-component system regulatory protein, LuxR family. (212 aa)
Sthe_3240PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type; KEGG: rhi:NGR_b01300 putative HTH-type transcriptional regulator. (176 aa)
Sthe_3218Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_0902 two component transcriptional regulator, LuxR family. (209 aa)
Sthe_3200PFAM: TadE family protein; KEGG: sfu:Sfum_1495 TadE family protein. (144 aa)
Sthe_3199PFAM: TadE family protein; KEGG: bpl:BURPS1106A_A2964 TadE-like protein. (132 aa)
Sthe_3198PFAM: Anti-sigma-K factor RskA; KEGG: ank:AnaeK_0242 Fe-S oxidoreductase. (256 aa)
Sthe_3197RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: mxa:MXAN_3686 ECF subfamily RNA polymerase sigma factor. (193 aa)
Sthe_3183PFAM: Cupin 2 conserved barrel domain protein; KEGG: ret:RHE_CH03293 hypothetical protein. (143 aa)
Sthe_3164RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: acp:A2cp1_3324 RNA polymerase, sigma-24 subunit, ECF subfamily. (307 aa)
Sthe_3158Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: esa:ESA_00782 transcriptional regulator NarP. (214 aa)
Sthe_3130RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (359 aa)
Sthe_3127Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; response regulator receiver; SMART: response regulator receiver; KEGG: hch:HCH_00579 response regulator. (256 aa)
Sthe_3104Hypothetical protein. (241 aa)
Sthe_3081CheA signal transduction histidine kinase; KEGG: sml:Smlt3670 putative gliding motility sensor histidine kinase response regulator fusion transcriptional regulatory protein; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein. (1032 aa)
Sthe_3075Multi-sensor signal transduction histidine kinase; KEGG: mxa:MXAN_7398 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAS domain containing protein. (936 aa)
Sthe_3067Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: afw:Anae109_3644 regulatory protein ArsR. (102 aa)
Sthe_3049PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: ade:Adeh_3844 response regulator receiver domain-containing protein. (125 aa)
Sthe_3042Transcriptional regulator, RpiR family; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: eta:ETA_32910 putative transcriptional regulator. (290 aa)
Sthe_3026PFAM: regulatory protein TetR; KEGG: scl:sce6236 TetR family transcriptional regulator. (210 aa)
Sthe_3010Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: dal:Dalk_3679 transcriptional regulator, ArsR family. (134 aa)
Sthe_2984Transcriptional regulator, MerR family; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: tgr:Tgr7_2809 putative transcriptional regulator, MerR family. (164 aa)
Sthe_2978Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: nmn:NMCC_1944 ferric uptake regulation protein; Belongs to the Fur family. (144 aa)
Sthe_2955Putative RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Tetratricopeptide TPR_2 repeat protein; KEGG: pap:PSPA7_4032 ECF subfamily RNA polymerase sigma factor. (418 aa)
Sthe_2937Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: afr:AFE_2796 transcriptional regulator, ArsR family. (235 aa)
Sthe_2918Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; SMART: regulatory protein MerR; KEGG: scl:sce8660 MerR family transcriptional regulator. (269 aa)
Sthe_2881PFAM: SNARE associated Golgi protein; KEGG: wsu:WS0200 hypothetical protein. (248 aa)
Sthe_2880PFAM: type IV pilus assembly PilZ; KEGG: gem:GM21_3602 type IV pilus assembly PilZ. (234 aa)
Sthe_2869Transcriptional regulator, MerR family; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; GAF domain protein; SMART: GAF domain protein; KEGG: bmj:BMULJ_01800 MerR family transcriptional regulator. (245 aa)
Sthe_2848PFAM: Dimethylmenaquinone methyltransferase; KEGG: bja:blr3842 hypothetical protein. (227 aa)
Sthe_2833Phage transcriptional regulator, AlpA; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Prophage CP4-57 regulatory; KEGG: vei:Veis_2614 phage transcriptional regulator, AlpA. (71 aa)
Sthe_2796Transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: gsu:GSU3370 GntR family transcriptional regulator. (248 aa)
Sthe_2783PFAM: transcriptional regulator PadR family protein; KEGG: bbt:BBta_0853 PadR family transcriptional regulator. (129 aa)
Sthe_2735PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: csa:Csal_0066 IclR family transcriptional regulator. (270 aa)
Sthe_2725KEGG: abo:ABO_2712 hypothetical protein. (247 aa)
Sthe_2695Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: gsu:GSU2016 sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein. (760 aa)
Sthe_2694Multi-sensor signal transduction histidine kinase; KEGG: scl:sce5443 protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (668 aa)
Sthe_2675PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: lhk:LHK_00225 BaeR. (132 aa)
Sthe_2666Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: afw:Anae109_3104 two component transcriptional regulator. (233 aa)
Sthe_2665Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0186 two-component histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein. (645 aa)
Sthe_2664PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type; KEGG: rhi:NGR_b01300 putative HTH-type transcriptional regulator. (173 aa)
Sthe_2661PFAM: Transcription regulator, AsnC-type-like; KEGG: afw:Anae109_0784 AsnC family transcriptional regulator. (76 aa)
Sthe_2631PFAM: Proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase. (306 aa)
Sthe_2601PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: reh:H16_A1299 transcriptional regulator, IclR- family. (274 aa)
Sthe_2566Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: cti:RALTA_A2846 putative transcriptional regulator, TetR/AcrR families. (211 aa)
Sthe_2537Transcriptional regulator/antitoxin, MazE; KEGG: atc:AGR_C_1711 plasmid stable inheritance protein. (85 aa)
Sthe_2526Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: scl:sce5225 protein kinase. (799 aa)
Sthe_2457PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: acr:Acry_0713 osmosensitive K+ channel signal transduction histidine kinase. (424 aa)
Sthe_2441PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_2962 response regulator. (127 aa)
Sthe_2411Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0428 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. (788 aa)
Sthe_2401Multi-sensor signal transduction histidine kinase; KEGG: ana:all5210 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; GAF domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (1448 aa)
Sthe_2390PFAM: Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: bld:BLi01191 hypothetical protein. (323 aa)
Sthe_2386Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: bha:BH2086 ArsR family transcriptional regulator. (103 aa)
Sthe_2385PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: lsp:Bsph_2868 hypothetical protein. (140 aa)
Sthe_2376PFAM: protein of unknown function DUF28; KEGG: rxy:Rxyl_1318 hypothetical protein. (248 aa)
Sthe_2353Transcriptional regulator, LuxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; regulatory protein LuxR; sigma-70 region 4 domain protein; KEGG: sth:STH2528 RNA polymerase ECF-type sigma factor. (198 aa)
Sthe_2348TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: sfu:Sfum_0409 transcriptional regulator, AbrB family. (100 aa)
Sthe_2346RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rca:Rcas_0988 ECF subfamily RNA polymerase sigma-24 factor. (181 aa)
Sthe_2338PFAM: protein of unknown function DUF161; KEGG: cbe:Cbei_1430 protein of unknown function DUF161. (238 aa)
Sthe_2322Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: hau:Haur_1099 ArsR family transcriptional regulator. (358 aa)
Sthe_2307Transcriptional regulator, CdaR; PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: msm:MSMEG_6492 GAF domain protein, putative. (645 aa)
Sthe_2252PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: afw:Anae109_2598 response regulator receiver protein. (124 aa)
Sthe_2246PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: pth:PTH_2212 phosphatase. (144 aa)
Sthe_2244Phage transcriptional regulator, AlpA; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Prophage CP4-57 regulatory; KEGG: sen:SACE_0466 hypothetical protein. (69 aa)
Sthe_2230Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: vvy:VVA0798 hypothetical protein. (71 aa)
Sthe_2225Transcriptional regulator, GntR family with aminotransferase domain protein; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sth:STH2754 class I aminotransferase protein. (504 aa)
Sthe_2198Histidine kinase; KEGG: hau:Haur_0906 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (538 aa)
Sthe_2197Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: hau:Haur_0905 two component transcriptional regulator. (236 aa)
Sthe_2190KEGG: rca:Rcas_2698 putative transmembrane anti- sigma factor. (396 aa)
Sthe_2189RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: rca:Rcas_2697 ECF subfamily RNA polymerase sigma-24 factor. (194 aa)
Sthe_2174RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: cts:Ctha_1394 RNA polymerase, sigma-24 subunit, ECF subfamily. (182 aa)
Sthe_2172Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: stp:Strop_3509 regulatory protein, ArsR. (124 aa)
rexCoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (230 aa)
Sthe_2135Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: fal:FRAAL6409 hypothetical protein. (182 aa)
Sthe_2129PFAM: helix-turn-helix HxlR type; transcriptional regulator PadR family protein; KEGG: rlt:Rleg2_5189 transcriptional regulator, HxlR family. (116 aa)
Sthe_2119Putative transcriptional regulator; PFAM: regulatory protein ArsR; Helix-turn-helix type 11 domain protein; KEGG: rca:Rcas_3726 putative transcriptional regulator. (244 aa)
Sthe_2104Glutaredoxin; Contains selenocysteine; PFAM: glutaredoxin; KEGG: fma:FMG_0548 glutaredoxin. (78 aa)
Sthe_2095Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: pfl:PFL_4031 DNA-binding protein. (68 aa)
Sthe_2084RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: ank:AnaeK_0241 RNA polymerase, sigma-24 subunit, ECF subfamily. (237 aa)
Sthe_2073Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: tfu:Tfu_2297 regulatory protein, MarR. (155 aa)
Sthe_2043RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family. (219 aa)
Sthe_2039Multi-sensor signal transduction histidine kinase; KEGG: cau:Caur_1171 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein. (523 aa)
Sthe_2031Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_1498 GAF sensor signal transduction histidine kinase. (383 aa)
Sthe_2027Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sth:STH415 two-component response regulator. (244 aa)
Sthe_2026Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: mta:Moth_1130 periplasmic sensor signal transduction histidine kinase. (493 aa)
Sthe_2015PFAM: ThiJ/PfpI domain protein; KEGG: mex:Mext_1154 ThiJ/PfpI domain-containing protein. (187 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (238 aa)
minECell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (95 aa)
mraZTIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: rca:Rcas_1104 MraZ protein; Belongs to the MraZ family. (142 aa)
nrdRATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (158 aa)
Sthe_1974TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; Elongation factor SelB winged helix 3; Elongation factor SelB winged helix 2; elongation factor Tu domain 2 protein; KEGG: cau:Caur_0243 selenocysteine-specific translation elongation factor. (630 aa)
Sthe_1941Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pth:PTH_0048 response regulator. (240 aa)
Sthe_1940Histidine kinase; KEGG: pth:PTH_0047 signal transduction protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (366 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (361 aa)
Sthe_18982'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (194 aa)
Sthe_1890PFAM: Proline dehydrogenase; KEGG: gka:GK3010 proline dehydrogenase. (316 aa)
Sthe_1862PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: afw:Anae109_2598 response regulator receiver protein. (135 aa)
Sthe_1849RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (341 aa)
Sthe_1845TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; KEGG: hau:Haur_0125 RNA polymerase, sigma 54 subunit, RpoN. (472 aa)
Sthe_1819PFAM: ferric-uptake regulator; KEGG: deh:cbdb_A24 FUR family transcriptional regulator; Belongs to the Fur family. (150 aa)
Sthe_1815PFAM: protein of unknown function DUF156; KEGG: cef:CE0406 hypothetical protein. (104 aa)
Sthe_1761TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: pla:Plav_3434 AbrB family transcriptional regulator. (97 aa)
Sthe_1755Putative transmembrane anti-sigma factor; KEGG: cau:Caur_1861 hypothetical protein. (249 aa)
Sthe_1746PFAM: Helix-turn-helix type 11 domain protein; KEGG: sfu:Sfum_2823 putative transcriptional regulator. (354 aa)
tsfTranslation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (186 aa)
lexASOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (213 aa)
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (800 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1173 aa)
Sthe_1677Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: cau:Caur_0999 regulatory protein TetR. (216 aa)
Sthe_1658Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: sth:STH627 hypothetical protein; Belongs to the ArsC family. (93 aa)
Sthe_1646Transcriptional regulator, HxlR family; PFAM: helix-turn-helix HxlR type; KEGG: nca:Noca_4912 helix-turn-helix, HxlR type. (253 aa)
Sthe_1617KEGG: hypothetical protein. (139 aa)
Sthe_1616Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: rrs:RoseRS_0939 histidine kinase. (218 aa)
Sthe_1615Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: rca:Rcas_1579 two component LuxR family transcriptional regulator. (234 aa)
tuf-2Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (200 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (241 aa)
Sthe_1603PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; KEGG: dth:DICTH_0982 two-component system, regulatory protein. (200 aa)
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (301 aa)
Sthe_1568KEGG: rca:Rcas_4339 hypothetical protein. (191 aa)
Sthe_1567PFAM: Roadblock/LC7 family protein; KEGG: hau:Haur_0932 roadblock/LC7 family protein. (179 aa)
Sthe_1565PFAM: Roadblock/LC7 family protein; KEGG: hau:Haur_0933 roadblock/LC7 family protein. (121 aa)
Sthe_1552Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: rxy:Rxyl_0160 two component transcriptional regulator, LuxR family. (211 aa)
Sthe_1551Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: rxy:Rxyl_0159 periplasmic sensor signal transduction histidine kinase. (437 aa)
Sthe_1546Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: stp:Strop_0845 regulatory protein, TetR. (203 aa)
Sthe_1521Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: dsy:DSY2922 hypothetical protein; Belongs to the Fur family. (142 aa)
Sthe_1487Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: dau:Daud_2104 helix-turn-helix domain- containing protein. (74 aa)
Sthe_1465TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cya:CYA_0769 thioredoxin. (237 aa)
hpfSigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (194 aa)
Sthe_1437Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; response regulator receiver; SMART: response regulator receiver; KEGG: saq:Sare_0404 two component transcriptional regulator. (254 aa)
recXRegulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. (222 aa)
Sthe_1396KEGG: rrs:RoseRS_0006 hypothetical protein. (267 aa)
Sthe_1380Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: scl:sce2129 MerR family transcriptional regulator. (148 aa)
Sthe_1375Transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: sco:SCO6808 transcription regulator ArsR. (118 aa)
Sthe_1372Transcriptional regulator, ArsR family; PFAM: Protein-tyrosine phosphatase, low molecular weight; regulatory protein ArsR; SMART: Protein-tyrosine phosphatase, low molecular weight; regulatory protein ArsR; KEGG: hau:Haur_3330 ArsR family transcriptional regulator. (270 aa)
Sthe_1367PFAM: Helix-turn-helix type 11 domain protein; KEGG: fra:Francci3_0312 putative transcriptional regulator. (324 aa)
Sthe_1366Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: rca:Rcas_1579 two component LuxR family transcriptional regulator. (249 aa)
Sthe_1270Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; response regulator receiver; Bacterio-opsin activator HTH domain protein; SMART: regulatory protein LuxR; response regulator receiver; KEGG: rxy:Rxyl_0094 two component transcriptional regulator, LuxR family. (219 aa)
Sthe_1269Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_0881 integral membrane sensor signal transduction histidine kinase. (567 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (633 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (443 aa)
Sthe_1242RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: sgr:SGR_2306 RNA polymerase ECF-subfamily sigma factor. (204 aa)
Sthe_1241KEGG: ace:Acel_0539 anti-sigma factor. (74 aa)
Sthe_1229Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: rha:RHA1_ro04495 transcriptional regulator. (549 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (610 aa)
sigA-2RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (390 aa)
Sthe_1184PFAM: protein of unknown function DUF152; KEGG: pth:PTH_1832 hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (282 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (204 aa)
Sthe_1168Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (97 aa)
Sthe_1146KEGG: ppd:Ppro_2865 hypothetical protein. (369 aa)
Sthe_1145KEGG: ppd:Ppro_2865 hypothetical protein. (375 aa)
Sthe_1115Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: hau:Haur_0838 two component, sigma54 specific, fis family transcriptional regulator. (465 aa)
greA-2GreA/GreB family elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (156 aa)
infA-2Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (91 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (701 aa)
Sthe_0984PFAM: protein of unknown function DUF55; KEGG: pho:PH1033 hypothetical protein. (158 aa)
Sthe_0911Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: hau:Haur_0906 integral membrane sensor signal transduction histidine kinase. (543 aa)
Sthe_0910Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sru:SRU_2488 response regulator DrrA. (240 aa)
Sthe_0867Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: rrs:RoseRS_0938 two component LuxR family transcriptional regulator. (242 aa)
Sthe_0841KEGG: bwe:BcerKBAB4_4831 TetR family transcriptional regulator. (190 aa)
Sthe_0816PFAM: biotin/lipoate A/B protein ligase; KEGG: afl:Aflv_1125 biotin operon repressor containing HTH and biotin-(acetyl-CoA carboxylase) ligase domains. (178 aa)
Sthe_0811PFAM: histidine kinase dimerisation and phosphoacceptor region; KEGG: rca:Rcas_1122 histidine kinase. (362 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
Sthe_0762Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rrs:RoseRS_1206 MarR family transcriptional regulator. (215 aa)
Sthe_0751Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: mta:Moth_1478 two component transcriptional regulator. (224 aa)
Sthe_0750Histidine kinase; KEGG: rrs:RoseRS_0613 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (464 aa)
sigARNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (538 aa)
prfBConserved hypothetical protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (369 aa)
hrcAHeat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (347 aa)
selAL-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (478 aa)
Sthe_0681PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: rxy:Rxyl_0929 transcriptional regulator, GntR family. (264 aa)
Sthe_0675RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: rrs:RoseRS_2793 ECF subfamily RNA polymerase sigma-24 factor. (208 aa)
Sthe_0649TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; KEGG: scl:sce1736 citrate synthase. (83 aa)
Sthe_0648PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: afw:Anae109_1850 response regulator receiver protein. (131 aa)
Sthe_0628Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: rce:RC1_3977 nitrite and nitric oxide reductase regulator. (248 aa)
Sthe_0609RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: rca:Rcas_0731 ECF subfamily RNA polymerase sigma-24 factor. (224 aa)
Sthe_0608Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: ttj:TTHA1352 response regulator. (237 aa)
Sthe_0597Histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; KEGG: gvi:gll1661 similar to two-component sensor histidine kinase. (489 aa)
Sthe_0596PFAM: response regulator receiver; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; HI0933 family protein; SMART: response regulator receiver; KEGG: gvi:glr0480 thioredoxin reductase carring response regulator receiver domain. (554 aa)
Sthe_0589KEGG: fjo:Fjoh_1028 hypothetical protein. (601 aa)
Sthe_0569RNA polymerase, sigma 28 subunit, FliA/WhiG; KEGG: ace:Acel_1546 RNA polymerase sigma factor WhiG; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein. (264 aa)
Sthe_0564PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: psb:Psyr_3488 anti-sigma-28 factor, FlgM. (105 aa)
fliWProtein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (145 aa)
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (83 aa)
Sthe_0518PFAM: response regulator receiver; Cobyrinic acid ac-diamide synthase; SMART: response regulator receiver; KEGG: rca:Rcas_1683 response regulator receiver protein. (421 aa)
Sthe_0470RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: pth:PTH_2134 DNA-directed RNA polymerase specialized sigma subunit, sigma24-like protein; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
Sthe_0469Putative transmembrane anti-sigma factor; KEGG: rca:Rcas_0510 serine/threonine protein kinase. (575 aa)
Sthe_0459TIGRFAM: translation elongation factor G; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: mta:Moth_1142 elongation factor G. (693 aa)
Sthe_0444KEGG: rrs:RoseRS_1536 hypothetical protein. (298 aa)
Sthe_0440Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: nis:NIS_0956 MerR family transcriptional regulator. (119 aa)
Sthe_0432PFAM: transcriptional regulator PadR family protein; KEGG: rxy:Rxyl_2708 transcriptional regulator, PadR family. (215 aa)
Sthe_0400Transcriptional regulator, MerR family; KEGG: rha:RHA1_ro05652 redox-sensitive transcriptional activator; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR. (153 aa)
Sthe_0397TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: mta:Moth_1653 BadM/Rrf2 family transcriptional regulator. (143 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (140 aa)
Sthe_0369Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: lac:LBA0078 putative response regulator. (233 aa)
Sthe_0368KEGG: det:DET0136 sensory box sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein. (598 aa)
Sthe_0362Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (231 aa)
Sthe_0353Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: fal:FRAAL1706 MarR family transcriptional regulator. (174 aa)
Sthe_0315PFAM: aminotransferase class I and II; KEGG: lch:Lcho_3539 GntR family transcriptional regulator. (402 aa)
Sthe_0285Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: nfa:nfa3720 putative transcriptional regulator. (122 aa)
Sthe_0269PFAM: Cold-shock protein DNA-binding; Ribonuclease B OB region domain; SMART: Cold shock protein; KEGG: cpo:COPRO5265_1161 hypothetical protein. (77 aa)
Sthe_0265Transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: msm:MSMEG_4057 transcriptional regulator, GntR family protein. (224 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (157 aa)
Sthe_0244Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: sth:STH2634 two-component sensor histidine kinase. (456 aa)
Sthe_0243Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: cau:Caur_3230 response regulator receiver. (223 aa)
Sthe_0238KEGG: hau:Haur_3291 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (485 aa)
Sthe_0235PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: rha:RHA1_ro08622 IclR family transcriptional regulator. (309 aa)
Sthe_0200Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: gtn:GTNG_3075 two-component response regulator. (223 aa)
Sthe_0199PFAM: histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: cau:Caur_0656 histidine kinase dimerisation and phosphoacceptor region. (420 aa)
Sthe_0198Putative signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; SMART: GAF domain protein; KEGG: rca:Rcas_3064 GAF sensor signal transduction histidine kinase. (780 aa)
Sthe_0182Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bcl:ABC0529 two-component response regulator. (231 aa)
Sthe_0181Histidine kinase; KEGG: bcl:ABC0528 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (477 aa)
Sthe_0156PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: sco:SCO1802 two-component system sensor kinase. (492 aa)
Sthe_0155Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: sth:STH923 two-component response regulator. (216 aa)
Sthe_0148TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ava:Ava_2654 thioredoxin; Belongs to the thioredoxin family. (108 aa)
Sthe_0135KEGG: ookinete protein. (600 aa)
Sthe_0121PFAM: TadE family protein; KEGG: nth:Nther_2320 TadE family protein. (143 aa)
Sthe_0120PFAM: TadE family protein; KEGG: rba:RB1154 hypothetical protein. (134 aa)
Sthe_0119KEGG: pzu:PHZ_c2994 hypothetical protein. (598 aa)
Sthe_0107Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: rxy:Rxyl_0881 transcriptional regulator, MarR family. (165 aa)
Sthe_0094Transcriptional regulator, LuxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; regulatory protein LuxR; sigma-70 region 4 domain protein; KEGG: rfr:Rfer_4146 sigma-24 (FecI-like); Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
Sthe_0075PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: mxa:MXAN_0675 hypothetical protein. (161 aa)
Sthe_0050TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; KEGG: rce:RC1_3519 DNA binding domain, excisionase family, putative. (149 aa)
Sthe_0039Transcriptional regulator, CdaR; KEGG: aha:AHA_0640 carbohydrate diacid regulator. (397 aa)
Sthe_0031PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mma:MM_1068 two-component response regulator. (133 aa)
Sthe_0027Diguanylate cyclase with PAS/PAC sensor; KEGG: sgr:SGR_2001 putative integral membrane phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein. (610 aa)
Sthe_0005Transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: cau:Caur_2267 GntR domain-containing protein. (246 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (471 aa)
Sthe_3340Hypothetical protein. (240 aa)
Sthe_3333Transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bmt:BSUIS_B1410 hypothetical protein. (261 aa)
Sthe_3327KEGG: scl:sce5225 protein kinase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; TPR repeat- containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: GGDEF domain containing protein; Tetratricopeptide repeat. (1156 aa)
Sthe_3323PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: shn:Shewana3_1959 two component transcriptional regulator. (132 aa)
Sthe_3316KEGG: scl:sce5225 protein kinase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; TPR repeat- containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: GGDEF domain containing protein; Tetratricopeptide repeat. (907 aa)
Sthe_3286Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: reh:H16_A2662 transcriptional regulator, MocR family. (405 aa)
Sthe_3284Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: har:HEAR1907 osmolarity response regulator. (310 aa)
Sthe_3274Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0589 multi-sensor signal transduction histidine kinase. (398 aa)
Sthe_3273Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: smd:Smed_5362 two component transcriptional regulator. (232 aa)
Sthe_3271TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: noc:Noc_2206 AbrB family transcriptional regulator. (79 aa)
Sthe_3268PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pla:Plav_0399 two component transcriptional regulator. (142 aa)
Sthe_3502PFAM: Proline dehydrogenase; KEGG: mxa:MXAN_7405 proline dehydrogenase. (325 aa)
Sthe_3494Transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bxe:Bxe_B2360 GntR family transcriptional regulator. (243 aa)
Sthe_3478TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: pla:Plav_3138 dihydrolipoamide dehydrogenase. (464 aa)
Sthe_3462PFAM: transcriptional regulator PadR family protein; KEGG: bvi:Bcep1808_0129 PadR family transcriptional regulator. (173 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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