STRINGSTRING
Sthe_1233 Sthe_1233 rplK rplK purF purF hemA hemA rpsP rpsP pheA pheA Sthe_1968 Sthe_1968 Sthe_2034 Sthe_2034 Sthe_3485 Sthe_3485 nuoN nuoN rpsS rpsS rplF rplF rpmJ rpmJ Sthe_1073 Sthe_1073 rplT rplT purD purD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_1233DNA-(apurinic or apyrimidinic site) lyase; KEGG: mxa:MXAN_6425 base excision DNA repair protein, HhH-GPD family; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein. (220 aa)
rplKRibosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (480 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (422 aa)
rpsPTIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; KEGG: lme:LEUM_1485 SSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family. (107 aa)
pheAPFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: rrs:RoseRS_1964 prephenate dehydratase. (286 aa)
Sthe_1968Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (387 aa)
Sthe_2034PFAM: Vitamin K epoxide reductase; SMART: Vitamin K epoxide reductase; KEGG: sth:STH2564 hypothetical protein. (149 aa)
Sthe_3485Mg-chelatase subunit ChlI-like protein; KEGG: CHLI1; CHLI1 (CHLORINA 42); magnesium chelatase; K03405 magnesium chelatase subunit ChlI. (465 aa)
nuoNProton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (498 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (94 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (181 aa)
rpmJTIGRFAM: ribosomal protein L36; PFAM: ribosomal protein L36; KEGG: lch:Lcho_3927 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
Sthe_1073KEGG: hau:Haur_2402 DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; iron-sulfur cluster loop. (247 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa)
purDKEGG: mta:Moth_2043 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. (429 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.