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Sthe_2052 Sthe_2052 nuoB nuoB nuoH nuoH Sthe_0300 Sthe_0300 Sthe_0593 Sthe_0593 Sthe_0631 Sthe_0631 Sthe_0637 Sthe_0637 Sthe_0752 Sthe_0752 Sthe_0988 Sthe_0988 Sthe_0996 Sthe_0996 Sthe_0999 Sthe_0999 Sthe_1238 Sthe_1238 Sthe_1239 Sthe_1239 Sthe_1582 Sthe_1582 Sthe_1583 Sthe_1583 Sthe_1584 Sthe_1584 nuoI nuoI Sthe_1835 Sthe_1835 Sthe_1836 Sthe_1836 Sthe_1922 Sthe_1922 Sthe_2053 Sthe_2053 Sthe_2159 Sthe_2159 Sthe_2165 Sthe_2165 Sthe_2200 Sthe_2200 Sthe_3191 Sthe_3191 Sthe_3192 Sthe_3192
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Sthe_2052PFAM: cytochrome c oxidase subunit II; blue (type 1) copper domain protein; KEGG: rrs:RoseRS_0933 cytochrome c oxidase, subunit II. (155 aa)
nuoBNADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (185 aa)
nuoHNADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (343 aa)
Sthe_0300KEGG: mgm:Mmc1_3623 proton-translocating NADH- quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (527 aa)
Sthe_0593KEGG: bbr:BB0993 hypothetical protein. (106 aa)
Sthe_0631Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (631 aa)
Sthe_0637KEGG: sth:STH2945 hypothetical protein. (450 aa)
Sthe_0752PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mav:MAV_0925 respiratory-chain NADH dehydrogenase 51 kd subunit family protein. (442 aa)
Sthe_0988KEGG: scl:sce8170 hypothetical protein. (422 aa)
Sthe_0996TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: sgr:SGR_2690 putative succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (233 aa)
Sthe_0999TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: cmi:CMM_0972 succinate dehydrogenase, cytochrome b subunit. (121 aa)
Sthe_1238PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: pth:PTH_2648 NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit. (575 aa)
Sthe_1239PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: tko:TK1614 NADH dehydrogenase subunit E. (180 aa)
Sthe_1582Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (345 aa)
Sthe_1583Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (611 aa)
Sthe_1584PFAM: cytochrome c oxidase subunit III; KEGG: sth:STH2098 cytochrome c oxidase subunit III. (208 aa)
nuoINADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (148 aa)
Sthe_1835PFAM: cytochrome c oxidase subunit II; KEGG: rrs:RoseRS_0933 cytochrome c oxidase, subunit II. (160 aa)
Sthe_1836PFAM: cytochrome c oxidase subunit I; KEGG: cau:Caur_2426 cytochrome-c oxidase; Belongs to the heme-copper respiratory oxidase family. (554 aa)
Sthe_19222-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; KEGG: dar:Daro_3183 7,8-dihydro-6- hydroxymethylpterin-pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. (167 aa)
Sthe_2053PFAM: cytochrome c oxidase subunit I; KEGG: cau:Caur_2426 cytochrome-c oxidase; Belongs to the heme-copper respiratory oxidase family. (561 aa)
Sthe_2159Hypothetical protein; KEGG: mxa:MXAN_5554 cytochrome c family protein. (227 aa)
Sthe_2165KEGG: lic:LIC10873 hypothetical protein. (176 aa)
Sthe_2200PFAM: cytochrome c class I; KEGG: lic:LIC10208 cytochrome c oxidase polypeptide II. (143 aa)
Sthe_3191PFAM: cytochrome c oxidase subunit II; KEGG: rso:RS02212 putative cytochrome c oxidase polypeptide II oxidoreductase protein. (183 aa)
Sthe_3192PFAM: cytochrome c oxidase subunit I; KEGG: bra:BRADO2260 putative cytochrome-c oxidase subunit I. (579 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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