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purD purD Sthe_0213 Sthe_0213 Sthe_0215 Sthe_0215 Sthe_0376 Sthe_0376 Sthe_0533 Sthe_0533 Sthe_0770 Sthe_0770 carB carB uvrA uvrA sucC sucC ddl ddl Sthe_2818 Sthe_2818 Sthe_2943 Sthe_2943
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purDKEGG: mta:Moth_2043 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. (429 aa)
Sthe_0213PFAM: RimK domain protein ATP-grasp; KEGG: sgr:SGR_3478 putative lysine biosynthesis enzyme LysX. (274 aa)
Sthe_0215TIGRFAM: lysine biosynthesis enzyme LysX; alpha-L- glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; KEGG: cau:Caur_0334 lysine biosynthesis enzyme LysX; Belongs to the RimK family. (298 aa)
Sthe_0376acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (457 aa)
Sthe_0533PFAM: CoA-binding domain protein; ATP-grasp domain protein; KEGG: bpy:Bphyt_4084 CoA-binding domain protein. (743 aa)
Sthe_0770KEGG: cau:Caur_2963 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; Belongs to the PEP-utilizing enzyme family. (877 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: det:DET1202 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1080 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (964 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (379 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (375 aa)
Sthe_2818PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; KEGG: gme:Gmet_2101 pyruvate phosphate dikinase, PEP/pyruvate-binding. (358 aa)
Sthe_2943TIGRFAM: lysine biosynthesis enzyme LysX; alpha-L- glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: afw:Anae109_2113 alpha-L-glutamate ligase; Belongs to the RimK family. (302 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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