STRINGSTRING
Sthe_2869 Sthe_2869 Sthe_3075 Sthe_3075 Sthe_3170 Sthe_3170 Sthe_3242 Sthe_3242 Sthe_3347 Sthe_3347 Sthe_3406 Sthe_3406 Sthe_0235 Sthe_0235 Sthe_0244 Sthe_0244 Sthe_0334 Sthe_0334 Sthe_0405 Sthe_0405 hrcA hrcA Sthe_0992 Sthe_0992 Sthe_1940 Sthe_1940 Sthe_2039 Sthe_2039 Sthe_2307 Sthe_2307 Sthe_2401 Sthe_2401 Sthe_2411 Sthe_2411 Sthe_2601 Sthe_2601 Sthe_2457 Sthe_2457 Sthe_2789 Sthe_2789 Sthe_0199 Sthe_0199 Sthe_2735 Sthe_2735 Sthe_2694 Sthe_2694 Sthe_2665 Sthe_2665 Sthe_0198 Sthe_0198 Sthe_0156 Sthe_0156
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_2869Transcriptional regulator, MerR family; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; GAF domain protein; SMART: GAF domain protein; KEGG: bmj:BMULJ_01800 MerR family transcriptional regulator. (245 aa)
Sthe_3075Multi-sensor signal transduction histidine kinase; KEGG: mxa:MXAN_7398 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAS domain containing protein. (936 aa)
Sthe_3170KEGG: scl:sce6351 protein kinase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; tyrosine protein kinase; Serine/threonine protein kinase-related; GAF domain protein; SMART: GGDEF domain containing protein; serine/threonine protein kinase; tyrosine protein kinase; GAF domain protein. (1765 aa)
Sthe_3242KEGG: afw:Anae109_4151 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein. (883 aa)
Sthe_3347KEGG: bph:Bphy_7756 PAS sensor protein; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein. (555 aa)
Sthe_3406KEGG: gur:Gura_1941 metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; metal dependent phophohydrolase; PFAM: GGDEF domain containing protein; GAF domain protein; metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: GGDEF domain containing protein; metal- dependent phosphohydrolase HD region; GAF domain protein. (1113 aa)
Sthe_0235PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: rha:RHA1_ro08622 IclR family transcriptional regulator. (309 aa)
Sthe_0244Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: sth:STH2634 two-component sensor histidine kinase. (456 aa)
Sthe_0334PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: amt:Amet_1620 putative GAF sensor protein. (162 aa)
Sthe_0405Diguanylate cyclase and metal dependent phosphohydrolase; KEGG: dau:Daud_0771 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; metal- dependent phosphohydrolase HD sub domain; GAF domain protein; Metal-dependent hydrolase HDOD; SMART: GGDEF domain containing protein; metal- dependent phosphohydrolase HD region; GAF domain protein. (888 aa)
hrcAHeat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (347 aa)
Sthe_0992PFAM: GAF domain protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: rca:Rcas_4451 signal transduction histidine kinase. (652 aa)
Sthe_1940Histidine kinase; KEGG: pth:PTH_0047 signal transduction protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (366 aa)
Sthe_2039Multi-sensor signal transduction histidine kinase; KEGG: cau:Caur_1171 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein. (523 aa)
Sthe_2307Transcriptional regulator, CdaR; PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: msm:MSMEG_6492 GAF domain protein, putative. (645 aa)
Sthe_2401Multi-sensor signal transduction histidine kinase; KEGG: ana:all5210 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; GAF domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (1448 aa)
Sthe_2411Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0428 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. (788 aa)
Sthe_2601PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: reh:H16_A1299 transcriptional regulator, IclR- family. (274 aa)
Sthe_2457PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: acr:Acry_0713 osmosensitive K+ channel signal transduction histidine kinase. (424 aa)
Sthe_2789KEGG: tbd:Tbd_2634 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; GAF domain protein; PAS domain containing protein. (747 aa)
Sthe_0199PFAM: histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: cau:Caur_0656 histidine kinase dimerisation and phosphoacceptor region. (420 aa)
Sthe_2735PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: csa:Csal_0066 IclR family transcriptional regulator. (270 aa)
Sthe_2694Multi-sensor signal transduction histidine kinase; KEGG: scl:sce5443 protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (668 aa)
Sthe_2665Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0186 two-component histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein. (645 aa)
Sthe_0198Putative signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; SMART: GAF domain protein; KEGG: rca:Rcas_3064 GAF sensor signal transduction histidine kinase. (780 aa)
Sthe_0156PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: sco:SCO1802 two-component system sensor kinase. (492 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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