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Sthe_0168 Sthe_0168 hldE hldE Sthe_0462 Sthe_0462 Sthe_0733 Sthe_0733 nnrE nnrE Sthe_1496 Sthe_1496 Sthe_1749 Sthe_1749 rbsK rbsK Sthe_3239 Sthe_3239
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sthe_0168PFAM: PfkB domain protein; KEGG: rrs:RoseRS_3963 ribokinase-like domain- containing protein. (298 aa)
hldECytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (507 aa)
Sthe_0462PFAM: PfkB domain protein; KEGG: gsu:GSU0692 carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (318 aa)
Sthe_0733PFAM: PfkB domain protein; KEGG: hypothetical protein; K00847 fructokinase. (328 aa)
nnrECarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (536 aa)
Sthe_1496TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cau:Caur_0373 phosphomethylpyrimidine kinase. (279 aa)
Sthe_1749PFAM: PfkB domain protein; KEGG: cau:Caur_2356 ribokinase-like domain- containing protein. (339 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
Sthe_3239PFAM: PfkB domain protein; KEGG: xcv:XCV0122 2-keto-3-deoxygluconate kinase. (322 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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