STRINGSTRING
Sthe_0368 Sthe_0368 Sthe_3347 Sthe_3347 Sthe_3274 Sthe_3274 Sthe_3242 Sthe_3242 Sthe_3081 Sthe_3081 Sthe_3075 Sthe_3075 Sthe_2694 Sthe_2694 Sthe_2665 Sthe_2665 Sthe_2457 Sthe_2457 Sthe_2411 Sthe_2411 Sthe_2401 Sthe_2401 Sthe_2198 Sthe_2198 Sthe_2039 Sthe_2039 Sthe_2031 Sthe_2031 Sthe_2026 Sthe_2026 Sthe_1940 Sthe_1940 Sthe_1616 Sthe_1616 mutL-2 mutL-2 Sthe_1551 Sthe_1551 Sthe_1269 Sthe_1269 gyrB gyrB Sthe_0992 Sthe_0992 Sthe_0911 Sthe_0911 mutL mutL Sthe_0811 Sthe_0811 Sthe_0750 Sthe_0750 Sthe_0597 Sthe_0597 Sthe_0244 Sthe_0244 Sthe_0199 Sthe_0199 Sthe_0198 Sthe_0198 Sthe_0181 Sthe_0181 Sthe_0156 Sthe_0156 Sthe_0083 Sthe_0083
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Sthe_0368KEGG: det:DET0136 sensory box sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein. (598 aa)
Sthe_3347KEGG: bph:Bphy_7756 PAS sensor protein; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein. (555 aa)
Sthe_3274Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0589 multi-sensor signal transduction histidine kinase. (398 aa)
Sthe_3242KEGG: afw:Anae109_4151 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein. (883 aa)
Sthe_3081CheA signal transduction histidine kinase; KEGG: sml:Smlt3670 putative gliding motility sensor histidine kinase response regulator fusion transcriptional regulatory protein; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein. (1032 aa)
Sthe_3075Multi-sensor signal transduction histidine kinase; KEGG: mxa:MXAN_7398 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAS domain containing protein. (936 aa)
Sthe_2694Multi-sensor signal transduction histidine kinase; KEGG: scl:sce5443 protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (668 aa)
Sthe_2665Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0186 two-component histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein. (645 aa)
Sthe_2457PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: acr:Acry_0713 osmosensitive K+ channel signal transduction histidine kinase. (424 aa)
Sthe_2411Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0428 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. (788 aa)
Sthe_2401Multi-sensor signal transduction histidine kinase; KEGG: ana:all5210 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; GAF domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein. (1448 aa)
Sthe_2198Histidine kinase; KEGG: hau:Haur_0906 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (538 aa)
Sthe_2039Multi-sensor signal transduction histidine kinase; KEGG: cau:Caur_1171 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein. (523 aa)
Sthe_2031Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_1498 GAF sensor signal transduction histidine kinase. (383 aa)
Sthe_2026Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: mta:Moth_1130 periplasmic sensor signal transduction histidine kinase. (493 aa)
Sthe_1940Histidine kinase; KEGG: pth:PTH_0047 signal transduction protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (366 aa)
Sthe_1616Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: rrs:RoseRS_0939 histidine kinase. (218 aa)
mutL-2DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (585 aa)
Sthe_1551Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: rxy:Rxyl_0159 periplasmic sensor signal transduction histidine kinase. (437 aa)
Sthe_1269Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_0881 integral membrane sensor signal transduction histidine kinase. (567 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (638 aa)
Sthe_0992PFAM: GAF domain protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: rca:Rcas_4451 signal transduction histidine kinase. (652 aa)
Sthe_0911Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: hau:Haur_0906 integral membrane sensor signal transduction histidine kinase. (543 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (578 aa)
Sthe_0811PFAM: histidine kinase dimerisation and phosphoacceptor region; KEGG: rca:Rcas_1122 histidine kinase. (362 aa)
Sthe_0750Histidine kinase; KEGG: rrs:RoseRS_0613 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (464 aa)
Sthe_0597Histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; KEGG: gvi:gll1661 similar to two-component sensor histidine kinase. (489 aa)
Sthe_0244Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: sth:STH2634 two-component sensor histidine kinase. (456 aa)
Sthe_0199PFAM: histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: cau:Caur_0656 histidine kinase dimerisation and phosphoacceptor region. (420 aa)
Sthe_0198Putative signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; SMART: GAF domain protein; KEGG: rca:Rcas_3064 GAF sensor signal transduction histidine kinase. (780 aa)
Sthe_0181Histidine kinase; KEGG: bcl:ABC0528 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (477 aa)
Sthe_0156PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; KEGG: sco:SCO1802 two-component system sensor kinase. (492 aa)
Sthe_0083KEGG: tte:TTE0010 DNA gyrase subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; DNA gyrase subunit B domain protein; ATP- binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein. (674 aa)
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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