STRINGSTRING
dlaT dlaT AOW45582.1 AOW45582.1 glo1 glo1 acsS acsS AOW45704.1 AOW45704.1 gloB gloB accA accA aarC aarC mqo mqo pdhD pdhD AOW46088.1 AOW46088.1 dlsT dlsT pdhA pdhA fumC fumC ackA ackA AOW46313.1 AOW46313.1 nifJ nifJ ghrA ghrA AOW46669.1 AOW46669.1 AOW46753.1 AOW46753.1 dld dld ldhD ldhD aldA aldA AOW47094.1 AOW47094.1 accD accD leuA leuA maeB maeB AOW47582.1 AOW47582.1 AOW47583.1 AOW47583.1 fumA fumA AOW47628.1 AOW47628.1 AOW47671.1 AOW47671.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dlaTAcetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AOW45582.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (486 aa)
glo1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (130 aa)
acsSacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (640 aa)
AOW45704.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (241 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
aarCacetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
pdhDDihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AOW46088.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (416 aa)
dlsTPyruvate dehydrogenase complex E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (451 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (336 aa)
fumCStress responsive protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (482 aa)
ackAHypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
AOW46313.1Catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
nifJPyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1195 aa)
ghrAGlyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AOW46669.1Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (891 aa)
AOW46753.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa)
ldhD2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
aldAAldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (482 aa)
AOW47094.1acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (301 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (529 aa)
maeBNAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
AOW47582.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
AOW47583.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa)
fumAFumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa)
AOW47628.1Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
AOW47671.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
Your Current Organism:
Acetobacter ascendens
NCBI taxonomy Id: 481146
Other names: A. ascendens, Acetobacter pasteurianus subsp. ascendens, Acetobacter pasteurianus subsp. paradoxus, Bacterium ascendans, CCUG 18128, LMD 51.1, LMD 53.6 [[Acetobacter pasteurianus subsp. paradoxus]], NCCB 51001, NCCB 53006 [[Acetobacter pasteurianus subsp. paradoxus]]
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