STRINGSTRING
glmU glmU ACX62385.1 ACX62385.1 ACX62424.1 ACX62424.1 murA murA ACX62589.1 ACX62589.1 ACX62606.1 ACX62606.1 ACX62877.1 ACX62877.1 ACX62943.1 ACX62943.1 uppP uppP ddl ddl ACX63183.1 ACX63183.1 ACX63252.1 ACX63252.1 ACX63387.1 ACX63387.1 ACX63442.1 ACX63442.1 ACX63679.1 ACX63679.1 murC murC mltG mltG ACX63890.1 ACX63890.1 ACX64073.1 ACX64073.1 ACX64093.1 ACX64093.1 murE murE murF murF mraY mraY murD murD murG murG murB murB murA-2 murA-2 ACX64149.1 ACX64149.1 ACX64421.1 ACX64421.1 ACX64439.1 ACX64439.1 ACX64473.1 ACX64473.1 ACX64748.1 ACX64748.1 ACX64764.1 ACX64764.1 mraY-2 mraY-2 ACX65002.1 ACX65002.1 ACX65074.1 ACX65074.1 ACX65102.1 ACX65102.1 ACX65279.1 ACX65279.1 uppP-2 uppP-2 ACX65396.1 ACX65396.1 ACX65438.1 ACX65438.1 ACX65490.1 ACX65490.1 ACX65565.1 ACX65565.1 ACX65647.1 ACX65647.1 ACX65693.1 ACX65693.1 ACX65723.1 ACX65723.1 ACX65969.1 ACX65969.1 murE-2 murE-2 murB-2 murB-2 ACX66347.1 ACX66347.1 ACX66385.1 ACX66385.1 ACX66455.1 ACX66455.1 amj amj ACX66564.1 ACX66564.1 murI murI ACX66693.1 ACX66693.1 ACX66705.1 ACX66705.1 ACX66709.1 ACX66709.1 ACX66852.1 ACX66852.1 murI-2 murI-2 ddl-2 ddl-2 uppP-3 uppP-3 ACX67374.1 ACX67374.1 uppP-4 uppP-4 ACX67538.1 ACX67538.1 ACX67569.1 ACX67569.1 ACX67579.1 ACX67579.1 ACX67683.1 ACX67683.1 ACX67705.1 ACX67705.1 ACX67851.1 ACX67851.1 ACX68009.1 ACX68009.1 ACX68017.1 ACX68017.1 ACX68095.1 ACX68095.1 ACX68096.1 ACX68096.1 murA-3 murA-3 ACX68120.1 ACX68120.1 ACX68189.1 ACX68189.1 ACX68192.1 ACX68192.1 ACX68213.1 ACX68213.1 ACX68282.1 ACX68282.1 ACX68514.1 ACX68514.1 ACX68515.1 ACX68515.1 ACX68540.1 ACX68540.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (464 aa)
ACX62385.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: pjd:Pjdr2_0090 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (472 aa)
ACX62424.1PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: pjd:Pjdr2_1285 phosphoesterase PA-phosphatase related. (174 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
ACX62589.1PFAM: Pectate lyase/Amb allergen; SMART: Pectate lyase/Amb allergen; KEGG: cpy:Cphy_1612 pectate lyase/Amb allergen. (683 aa)
ACX62606.1Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; response regulator receiver; glycoside hydrolase family 2 sugar binding; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; KEGG: dsy:DSY0539 hypothetical protein. (979 aa)
ACX62877.1PFAM: glycosidase PH1107-related; KEGG: pjd:Pjdr2_5412 glycosidase PH1107-related. (353 aa)
ACX62943.1TIGRFAM: spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; KEGG: bbe:BBR47_41010 putative spore cortex-lytic enzyme precursor. (219 aa)
uppPUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (280 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (364 aa)
ACX63183.1TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: pjd:Pjdr2_0826 cell envelope-related transcriptional attenuator. (362 aa)
ACX63252.1PFAM: beta-lactamase; KEGG: sth:STH302 putative beta-lactamase. (381 aa)
ACX63387.1Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: cth:Cthe_1585 signal transduction histidine kinase, LytS. (566 aa)
ACX63442.1TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: pjd:Pjdr2_0826 cell envelope-related transcriptional attenuator. (318 aa)
ACX63679.1PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: pjd:Pjdr2_5381 peptidase M15B and M15C dd-carboxypeptidase VanY/endolysin. (197 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (458 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (347 aa)
ACX63890.1Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: pjd:Pjdr2_4338 penicillin-binding protein transpeptidase. (596 aa)
ACX64073.1TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: pjd:Pjdr2_3915 cell envelope-related transcriptional attenuator. (367 aa)
ACX64093.1KEGG: pjd:Pjdr2_3896 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; Penicillin-binding protein dimerisation domain; SMART: PASTA domain containing protein. (768 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (494 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (473 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (321 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (477 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (369 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (301 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (427 aa)
ACX64149.1PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: pjd:Pjdr2_3504 ErfK/YbiS/YcfS/YnhG family protein. (112 aa)
ACX64421.1Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: pjd:Pjdr2_2338 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (396 aa)
ACX64439.1PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; beta-lactamase; KEGG: pjd:Pjdr2_2360 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Belongs to the peptidase S11 family. (394 aa)
ACX64473.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)
ACX64748.1PFAM: cell wall hydrolase SleB; KEGG: bbe:BBR47_15960 cell wall hydrolase. (140 aa)
ACX64764.1PFAM: sulfatase; KEGG: pjd:Pjdr2_1197 sulfatase; Belongs to the LTA synthase family. (641 aa)
mraY-2Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (319 aa)
ACX65002.1PFAM: glycosidase PH1107-related; KEGG: dps:DP2454 hypothetical protein. (333 aa)
ACX65074.1PFAM: glycosidase PH1107-related; KEGG: pjd:Pjdr2_5077 glycosidase PH1107-related. (338 aa)
ACX65102.1KEGG: bcv:Bcav_3362 hypothetical protein. (737 aa)
ACX65279.1PFAM: Pectinesterase; KEGG: bpu:BPUM_1808 pectinesterase. (309 aa)
uppP-2Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (267 aa)
ACX65396.1Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: pjd:Pjdr2_1761 signal transduction histidine kinase, LytS. (609 aa)
ACX65438.1KEGG: saq:Sare_4368 serine-type D-Ala-D-Ala carboxypeptidase. (156 aa)
ACX65490.1Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: pjd:Pjdr2_5067 histidine kinase. (629 aa)
ACX65565.1Signal transduction histidine kinase, LytS; PFAM: histidine kinase HAMP region domain protein; histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; KEGG: cce:Ccel_1250 signal transduction histidine kinase, LytS. (576 aa)
ACX65647.1PFAM: glycosidase PH1107-related; KEGG: dps:DP2454 hypothetical protein. (337 aa)
ACX65693.1PFAM: beta-lactamase; KEGG: ami:Amir_3698 beta-lactamase. (492 aa)
ACX65723.1Beta-lactamase; PFAM: penicillin-binding protein transpeptidase; KEGG: bsu:BSU02090 hypothetical protein. (269 aa)
ACX65969.1PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: afl:Aflv_0415 membrane-associated phospholipid phosphatase. (178 aa)
murE-2UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (502 aa)
murB-2UDP-N-acetylmuramate dehydrogenase; Cell wall formation. (343 aa)
ACX66347.1TIGRFAM: spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; KEGG: pjd:Pjdr2_3389 spore cortex-lytic enzyme. (270 aa)
ACX66385.1KEGG: pjd:Pjdr2_3422 hypothetical protein. (204 aa)
ACX66455.1KEGG: pjd:Pjdr2_3482 hypothetical protein; Belongs to the UPF0109 family. (76 aa)
amjConserved hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (263 aa)
ACX66564.1Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: pjd:Pjdr2_4869 peptidoglycan glycosyltransferase. (693 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (258 aa)
ACX66693.1Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: cce:Ccel_1250 signal transduction histidine kinase, LytS. (593 aa)
ACX66705.1PFAM: glycosidase PH1107-related; KEGG: pjd:Pjdr2_5077 glycosidase PH1107-related. (338 aa)
ACX66709.1Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: pjd:Pjdr2_4869 peptidoglycan glycosyltransferase. (680 aa)
ACX66852.1PFAM: sulfatase; KEGG: pjd:Pjdr2_2091 sulfatase; Belongs to the LTA synthase family. (661 aa)
murI-2Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (268 aa)
ddl-2D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (305 aa)
uppP-3Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (274 aa)
ACX67374.1PFAM: FG-GAP repeat protein; KEGG: pjd:Pjdr2_2482 FG-GAP repeat protein. (858 aa)
uppP-4Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (270 aa)
ACX67538.1TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: pjd:Pjdr2_4992 cell envelope-related transcriptional attenuator. (311 aa)
ACX67569.1PFAM: cell wall hydrolase SleB; KEGG: bsu:BSU13820 hypothetical protein. (298 aa)
ACX67579.1PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2; KEGG: bbe:BBR47_53540 putative peptidoglycan hydrolase. (261 aa)
ACX67683.1Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: pjd:Pjdr2_4869 peptidoglycan glycosyltransferase. (684 aa)
ACX67705.1PFAM: Peptidase M23; KEGG: pjd:Pjdr2_1202 peptidase M23. (360 aa)
ACX67851.1PFAM: Glycosyl transferase, family 4, conserved region; KEGG: pjd:Pjdr2_0539 glycosyl transferase family 4. (320 aa)
ACX68009.1PFAM: glycosyl transferase family 2; KEGG: cbe:Cbei_4758 glycosyl transferase family protein. (303 aa)
ACX68017.1N-acetylglucosamine-1-phosphate uridyltransferase; KEGG: gbm:Gbem_1609 WxcM domain protein. (188 aa)
ACX68095.1PFAM: Glycosyl transferase, family 4, conserved region; KEGG: pjd:Pjdr2_5783 glycosyl transferase family 4. (396 aa)
ACX68096.1Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. (252 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (449 aa)
ACX68120.1KEGG: pjd:Pjdr2_5827 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (385 aa)
ACX68189.1PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bbe:BBR47_00150 D-alanyl-D-alanine carboxypeptidase precursor; Belongs to the peptidase S11 family. (336 aa)
ACX68192.1KEGG: aoe:Clos_0616 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; 5TM Receptors of the LytS-YhcK type transmembrane region; SMART: GGDEF domain containing protein. (370 aa)
ACX68213.1PFAM: sulfatase; KEGG: pjd:Pjdr2_5894 sulfatase; Belongs to the LTA synthase family. (619 aa)
ACX68282.1Signal transduction histidine kinase, LytS; KEGG: bbe:BBR47_21770 two-component sensor histidine kinase; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (588 aa)
ACX68514.1TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: efa:EF1212 transcriptional regulator. (328 aa)
ACX68515.1PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bha:BH0021 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (323 aa)
ACX68540.1PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: pjd:Pjdr2_6288 single-stranded nucleic acid binding R3H domain protein. (262 aa)
Your Current Organism:
Paenibacillus sp. Y412MC10
NCBI taxonomy Id: 481743
Other names: P. sp. Y412MC10
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