(77 nodes) Drug ADME network (Absidia glauca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A163JHZ2	NDK domain-containing protein; Belongs to the NDK family. (227 aa)
	A0A163JK96	Uncharacterized protein. (544 aa)
	A0A163JKD7	Uncharacterized protein. (684 aa)
	A0A163JN58	Uncharacterized protein. (921 aa)
	A0A163JPM7	Uncharacterized protein. (295 aa)
	A0A163JQ22	Velvet domain-containing protein. (255 aa)
	A0A163JRI1	Uncharacterized protein. (1499 aa)
	A0A163JS65	Uncharacterized protein. (1337 aa)
	A0A163K231	Uncharacterized protein. (1344 aa)
	A0A163K2L8	Uncharacterized protein. (896 aa)
	A0A163K2P2	Uncharacterized protein. (1605 aa)
	A0A163K757	Uncharacterized protein. (522 aa)
	A0A163KPF6	Uncharacterized protein. (629 aa)
	A0A163KSH1	Uncharacterized protein. (445 aa)
	A0A163LVE8	PfkB domain-containing protein. (347 aa)
	A0A163LWJ0	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (494 aa)
	A0A163M5T2	Uncharacterized protein. (1316 aa)
	A0A163MCT4	Uncharacterized protein. (1534 aa)
	A0A163MJ87	Uncharacterized protein. (1095 aa)
	A0A163ML60	Uncharacterized protein. (1605 aa)
	A0A168LXT2	Velvet domain-containing protein. (282 aa)
	A0A168LU91	N-acetyltransferase domain-containing protein. (328 aa)
	A0A168LTU9	ABC transmembrane type-1 domain-containing protein. (716 aa)
	A0A168LQV0	Uncharacterized protein. (1485 aa)
	A0A168LJY6	Uncharacterized protein. (151 aa)
	A0A168KRK8	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (536 aa)
	A0A168KRT2	Uncharacterized protein. (180 aa)
	A0A168KSP5	Aldo_ket_red domain-containing protein. (309 aa)
	A0A168KLM7	Uncharacterized protein. (1295 aa)
	A0A163KB33	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (556 aa)
	A0A163TIU1	Aldo_ket_red domain-containing protein. (278 aa)
	A0A163TI49	A_deaminase domain-containing protein. (347 aa)
	A0A163MMQ2	Aldo_ket_red domain-containing protein. (321 aa)
	A0A170ALW8	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (319 aa)
	A0A168T5K9	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (524 aa)
	A0A168S9S0	Uncharacterized protein. (1339 aa)
	A0A168S633	Uncharacterized protein. (534 aa)
	A0A168RUQ6	Guanylate kinase-like domain-containing protein. (198 aa)
	A0A168RR45	Uncharacterized protein. (1539 aa)
	A0A168RJV6	Uncharacterized protein. (584 aa)
	A0A168RBE8	Uncharacterized protein. (501 aa)
	A0A168R293	Uncharacterized protein. (464 aa)
	A0A168QRD9	HMG box domain-containing protein. (608 aa)
	A0A168QQ69	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (533 aa)
	A0A168QNP0	Uncharacterized protein; Belongs to the peptidase S8 family. (912 aa)
	A0A168QK59	Uncharacterized protein. (1518 aa)
	A0A168QCG6	Uncharacterized protein. (346 aa)
	A0A168Q7R7	Uncharacterized protein. (446 aa)
	A0A168Q3E2	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (152 aa)
	A0A168Q0P7	Nucleoside diphosphate kinase. (148 aa)
	A0A168PTL1	PH domain-containing protein. (1048 aa)
	A0A168PJK8	Uncharacterized protein. (676 aa)
	A0A168PET7	Aldo_ket_red domain-containing protein. (321 aa)
	A0A168NYK1	M20_dimer domain-containing protein. (474 aa)
	A0A168NV68	Uncharacterized protein. (391 aa)
	A0A168NTQ3	Uncharacterized protein. (1586 aa)
	A0A168NEG1	Uncharacterized protein. (566 aa)
	A0A168N1P1	Velvet domain-containing protein. (493 aa)
	A0A168MYI3	Guanylate kinase-like domain-containing protein. (191 aa)
	A0A168MQE0	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (464 aa)
	A0A168MPP6	Aldo_ket_red domain-containing protein. (323 aa)
	A0A168MA68	Aldo_ket_red domain-containing protein. (321 aa)
	A0A168M5S6	WD_REPEATS_REGION domain-containing protein. (887 aa)
	A0A168M4Y9	Aldo_ket_red domain-containing protein. (296 aa)
	A0A168M4L3	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (521 aa)
	A0A168M0S1	Velvet domain-containing protein. (1094 aa)
	A0A163ITU7	Pribosyltran domain-containing protein. (208 aa)
	A0A163ITW9	Nucleoside diphosphate kinase. (148 aa)
	A0A163IVP9	ABC transporter domain-containing protein. (129 aa)
	A0A163J6L9	Uncharacterized protein. (1279 aa)
	A0A163JAD0	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (188 aa)
	A0A163JD02	Sterol 3-beta-glucosyltransferase; Belongs to the glycosyltransferase 28 family. (1175 aa)
	A0A163JDA6	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (368 aa)
	A0A163JF39	Uncharacterized protein. (599 aa)
	A0A163JFD2	Aldo_ket_red domain-containing protein. (309 aa)
	A0A163JG75	Uncharacterized protein. (1569 aa)
	A0A163JHH0	Uncharacterized protein. (592 aa)

Your Current Organism:

Absidia glauca

NCBI taxonomy Id: 4829
Other names: A. glauca, CBS 101.08, MUCL 10044

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A163ITU7	A0A163ITW9	Pribosyltran domain-containing protein.	Nucleoside diphosphate kinase.	0.722
A0A163ITU7	A0A163JAD0	Pribosyltran domain-containing protein.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.810
A0A163ITU7	A0A163JHZ2	Pribosyltran domain-containing protein.	NDK domain-containing protein; Belongs to the NDK family.	0.722
A0A163ITU7	A0A163JK96	Pribosyltran domain-containing protein.	Uncharacterized protein.	0.869
A0A163ITU7	A0A163KSH1	Pribosyltran domain-containing protein.	Uncharacterized protein.	0.493
A0A163ITU7	A0A163LVE8	Pribosyltran domain-containing protein.	PfkB domain-containing protein.	0.841
A0A163ITU7	A0A163LWJ0	Pribosyltran domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.862
A0A163ITU7	A0A163TI49	Pribosyltran domain-containing protein.	A_deaminase domain-containing protein.	0.850
A0A163ITU7	A0A168MYI3	Pribosyltran domain-containing protein.	Guanylate kinase-like domain-containing protein.	0.829
A0A163ITU7	A0A168NEG1	Pribosyltran domain-containing protein.	Uncharacterized protein.	0.869
A0A163ITU7	A0A168Q0P7	Pribosyltran domain-containing protein.	Nucleoside diphosphate kinase.	0.722
A0A163ITU7	A0A168Q3E2	Pribosyltran domain-containing protein.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.677
A0A163ITU7	A0A168Q7R7	Pribosyltran domain-containing protein.	Uncharacterized protein.	0.493
A0A163ITU7	A0A168RUQ6	Pribosyltran domain-containing protein.	Guanylate kinase-like domain-containing protein.	0.829
A0A163ITU7	A0A168T5K9	Pribosyltran domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.862
A0A163ITU7	A0A170ALW8	Pribosyltran domain-containing protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.887
A0A163ITW9	A0A163ITU7	Nucleoside diphosphate kinase.	Pribosyltran domain-containing protein.	0.722
A0A163ITW9	A0A163JAD0	Nucleoside diphosphate kinase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.824
A0A163ITW9	A0A168MYI3	Nucleoside diphosphate kinase.	Guanylate kinase-like domain-containing protein.	0.759
A0A163ITW9	A0A168Q3E2	Nucleoside diphosphate kinase.	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.	0.641