(87 nodes) Glutathione metabolism network (Absidia glauca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A168NYK1	M20_dimer domain-containing protein. (474 aa)
	A0A168NWE2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (434 aa)
	A0A168NTJ0	Uncharacterized protein. (144 aa)
	A0A168NTI3	F-box domain-containing protein. (624 aa)
	A0A168NNL6	Aminopeptidase. (874 aa)
	A0A168NMW8	Uncharacterized protein. (323 aa)
	A0A168N8U5	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
	A0A168N675	Uncharacterized protein. (476 aa)
	A0A168MXG7	Uncharacterized protein. (317 aa)
	A0A168MTF6	GST N-terminal domain-containing protein. (323 aa)
	A0A168MR78	Glutathione synthetase. (441 aa)
	A0A168M4P2	Uncharacterized protein. (133 aa)
	A0A168LR61	Peroxidase; Belongs to the peroxidase family. (359 aa)
	A0A168LQR4	Aldo_ket_red domain-containing protein. (275 aa)
	A0A168L8U1	Uncharacterized protein. (443 aa)
	A0A168L7E9	F-box domain-containing protein. (531 aa)
	A0A168L4G0	Peroxidase; Belongs to the peroxidase family. (271 aa)
	A0A168L223	CYTOSOL_AP domain-containing protein. (564 aa)
	A0A168L1Q3	Thioredoxin domain-containing protein. (216 aa)
	A0A168KNL0	GST C-terminal domain-containing protein. (233 aa)
	A0A163MUQ8	Uncharacterized protein. (1304 aa)
	A0A163ML53	Aldo_ket_red domain-containing protein. (260 aa)
	A0A163MBL9	Uncharacterized protein. (354 aa)
	A0A163M040	Uncharacterized protein. (348 aa)
	A0A163LSY3	Uncharacterized protein. (568 aa)
	A0A163KT95	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (485 aa)
	A0A163KPF6	Uncharacterized protein. (629 aa)
	A0A163KNM9	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (517 aa)
	A0A163KMN8	Uncharacterized protein. (241 aa)
	A0A163IRK2	F-box domain-containing protein. (665 aa)
	A0A163IWY6	GST N-terminal domain-containing protein. (558 aa)
	A0A163IYL0	Uncharacterized protein. (465 aa)
	A0A163J2R7	Peroxidase; Belongs to the peroxidase family. (349 aa)
	A0A163J5T1	Aminopeptidase. (915 aa)
	A0A163J7Z7	F-box domain-containing protein. (354 aa)
	A0A163J931	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (431 aa)
	A0A163JAL9	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
	A0A163JE07	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (294 aa)
	A0A163JFS5	Uncharacterized protein; Belongs to the GST superfamily. (194 aa)
	A0A163JHH0	Uncharacterized protein. (592 aa)
	A0A163JJ40	F-box domain-containing protein. (718 aa)
	A0A163JKD6	Uncharacterized protein; Belongs to the GST superfamily. (224 aa)
	A0A163JKE4	Thioredoxin domain-containing protein. (216 aa)
	A0A163JWR3	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (520 aa)
	A0A163JZL3	Uncharacterized protein. (348 aa)
	A0A163K194	Uncharacterized protein. (240 aa)
	A0A163K667	Uncharacterized protein. (535 aa)
	A0A163K794	Uncharacterized protein. (187 aa)
	A0A163KEC9	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (476 aa)
	A0A163KFH8	Uncharacterized protein. (478 aa)
	A0A163KLX8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (777 aa)
	A0A168RX54	GST C-terminal domain-containing protein. (133 aa)
	A0A168RX34	GST N-terminal domain-containing protein. (101 aa)
	A0A168T307	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (500 aa)
	A0A168TA53	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (166 aa)
	A0A168SVW7	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (816 aa)
	A0A168SQ67	Uncharacterized protein. (377 aa)
	A0A168SF71	Uncharacterized protein. (628 aa)
	A0A168RTQ5	Glutaredoxin domain-containing protein. (100 aa)
	A0A168RS08	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (469 aa)
	A0A168RL89	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (96 aa)
	A0A168RKZ9	Uncharacterized protein; Belongs to the GST superfamily. (227 aa)
	A0A168RKP1	Uncharacterized protein. (241 aa)
	A0A168RJV6	Uncharacterized protein. (584 aa)
	A0A168RBW8	Uncharacterized protein. (222 aa)
	A0A168RBE8	Uncharacterized protein. (501 aa)
	A0A168RA13	J domain-containing protein. (563 aa)
	A0A168R8L1	Ubiquitin_4 domain-containing protein. (148 aa)
	A0A168R6I4	Uncharacterized protein. (652 aa)
	A0A168QZV5	CYTOSOL_AP domain-containing protein. (552 aa)
	A0A168QTR6	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (199 aa)
	A0A168QRD9	HMG box domain-containing protein. (608 aa)
	A0A168QQ43	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (470 aa)
	A0A168QNN2	Uncharacterized protein. (221 aa)
	A0A168QK96	Uncharacterized protein. (370 aa)
	A0A168QH54	Uncharacterized protein. (151 aa)
	A0A168QE64	Uncharacterized protein. (722 aa)
	A0A168Q3P9	F-box domain-containing protein. (399 aa)
	A0A168PRW9	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (504 aa)
	A0A168PJK8	Uncharacterized protein. (676 aa)
	A0A168PH61	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (790 aa)
	A0A168PG91	F-box domain-containing protein. (739 aa)
	A0A168PFA2	Uncharacterized protein. (149 aa)
	A0A168PEX3	F-box domain-containing protein. (435 aa)
	A0A168PDU6	6PGD domain-containing protein. (358 aa)
	A0A168PAN2	Uncharacterized protein. (125 aa)
	A0A168P6B4	F-box domain-containing protein. (552 aa)

Your Current Organism:

Absidia glauca

NCBI taxonomy Id: 4829
Other names: A. glauca, CBS 101.08, MUCL 10044

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A163IWY6	A0A163JFS5	GST N-terminal domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.710
A0A163IWY6	A0A163JHH0	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.521
A0A163IWY6	A0A163JKE4	GST N-terminal domain-containing protein.	Thioredoxin domain-containing protein.	0.676
A0A163IWY6	A0A163K194	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.589
A0A163IWY6	A0A163K794	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.655
A0A163IWY6	A0A163KEC9	GST N-terminal domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.670
A0A163IWY6	A0A163KPF6	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.521
A0A163IWY6	A0A168L1Q3	GST N-terminal domain-containing protein.	Thioredoxin domain-containing protein.	0.676
A0A163IWY6	A0A168MR78	GST N-terminal domain-containing protein.	Glutathione synthetase.	0.808
A0A163IWY6	A0A168MXG7	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.589
A0A163IWY6	A0A168N675	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.589
A0A163IWY6	A0A168NMW8	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.589
A0A163IWY6	A0A168PJK8	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.521
A0A163IWY6	A0A168QNN2	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.655
A0A163IWY6	A0A168QQ43	GST N-terminal domain-containing protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.670
A0A163IWY6	A0A168QTR6	GST N-terminal domain-containing protein.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.748
A0A163IWY6	A0A168RBE8	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.504
A0A163IWY6	A0A168RJV6	GST N-terminal domain-containing protein.	Uncharacterized protein.	0.504
A0A163IWY6	A0A168RL89	GST N-terminal domain-containing protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.680
A0A163IWY6	A0A168RX34	GST N-terminal domain-containing protein.	GST N-terminal domain-containing protein.	0.655