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mdh mdh acnA acnA icd icd gltA-2 gltA-2 merA merA lpdA lpdA pdhC pdhC fumB_2 fumB_2 porC porC porB porB porA_1 porA_1 boxA boxA EEC54067.1 EEC54067.1 nifJ nifJ cfiA cfiA EEC53506.1 EEC53506.1 EEC52768.1 EEC52768.1 EEC52769.1 EEC52769.1 pckA pckA sdhC sdhC sdhA sdhA frdB frdB lpdA-2 lpdA-2 mdh_2 mdh_2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (313 aa)
acnAKEGG: bth:BT2072 0. aconitate hydratase K01681; Psort location: Cytoplasmic, score: 9.26. (747 aa)
icdDehydrogenase, isocitrate/isopropylmalate family; KEGG: bth:BT2071 9.2e-177 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 9.97. (385 aa)
gltA-2KEGG: bth:BT2070 3.3e-227 citrate synthase K01647; Psort location: Cytoplasmic, score: 9.26. (447 aa)
merAKEGG: eci:UTI89_C0327 1.4e-107 ykgC; probable pyridine nucleotide-disulfide oxidoreductase YkgC; Psort location: Cytoplasmic, score: 9.26. (458 aa)
lpdADihydrolipoyl dehydrogenase; KEGG: bfr:BF1618 2.0e-190 dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.26. (449 aa)
pdhC2-oxo acid dehydrogenase acyltransferase (catalytic domain); KEGG: bfs:BF1635 8.7e-165 putative dihydrolipoamide acetyltransferase K00680; Psort location: Cytoplasmic, score: 9.26. (433 aa)
fumB_2Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (546 aa)
porC2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit; KEGG: bth:BT0329 3.7e-86 vorA; ketoisovalerate oxidoreductase subunit vorA K00186. (180 aa)
porBThiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; KEGG: bth:BT0330 4.7e-118 vorA; ketoisovalerate oxidoreductase subunit vorA K00186. (254 aa)
porA_1Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; KEGG: bfr:BF1648 4.4e-177 vorB; ketoisovalerate oxidoreductase subunit VorB K00174; Psort location: Cytoplasmic, score: 8.96. (361 aa)
boxA4Fe-4S binding domain protein; KEGG: bfr:BF1649 1.8e-36 hypothetical protein K00176; Psort location: Cytoplasmic, score: 8.96. (75 aa)
EEC54067.1KEGG: bth:BT0429 3.7e-86 iorB; indolepyruvate oxidoreductase subunit iorB K00180. (193 aa)
nifJKEGG: bth:BT1747 0. pyruvate-flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96. (1185 aa)
cfiABiotin-requiring enzyme; KEGG: bth:BT1697 0. pyruvate carboxylase subunit B K01960. (611 aa)
EEC53506.1HMGL-like protein; KEGG: bth:BT1697 1.2e-183 pyruvate carboxylase subunit B K01960; Psort location: Cytoplasmic, score: 8.96. (591 aa)
EEC52768.12-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: bth:BT2836 1.6e-252 korA; 2-oxoglutarate synthase subunit korA K00174. (615 aa)
EEC52769.1Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; KEGG: bth:BT2837 1.1e-155 korB; 2-oxoglutarate synthase subunit korB K00175; Psort location: Cytoplasmic, score: 8.96. (334 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (535 aa)
sdhCSuccinate dehydrogenase cytochrome B subunit, b558 family; KEGG: bth:BT3053 3.1e-114 putative cytochrome B subunit K00241; Psort location: CytoplasmicMembrane, score: 10.00. (234 aa)
sdhAKEGG: bth:BT3054 0. succinate dehydrogenase flavoprotein subunit K00239. (648 aa)
frdBSuccinate dehydrogenase/fumarate reductase iron-sulfur subunit; KEGG: bth:BT3055 3.7e-134 succinate dehydrogenase iron-sulfur protein K00240. (251 aa)
lpdA-2Dihydrolipoyl dehydrogenase; KEGG: bfr:BF0024 3.7e-196 dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.26. (461 aa)
mdh_2Lactate/malate dehydrogenase, NAD binding domain protein; KEGG: bth:BT2510 1.8e-139 malate dehydrogenase K00026; Psort location: Cytoplasmic, score: 9.97; Belongs to the LDH/MDH superfamily. (333 aa)
Your Current Organism:
Bacteroides eggerthii
NCBI taxonomy Id: 483216
Other names: B. eggerthii DSM 20697, Bacteroides eggerthii ATCC 27754, Bacteroides eggerthii DSM 20697, Bacteroides eggerthii str. DSM 20697, Bacteroides eggerthii strain DSM 20697
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