STRINGSTRING
GCA_001660385_00841 GCA_001660385_00841 lexA lexA NI17_05800 NI17_05800 NI17_05840 NI17_05840 GCA_001660385_02811 GCA_001660385_02811 NI17_22550 NI17_22550 NI17_23010 NI17_23010 NI17_21105 NI17_21105 NI17_01345 NI17_01345 NI17_14325 NI17_14325 NI17_09215 NI17_09215 NI17_06880 NI17_06880 NI17_08970 NI17_08970 NI17_15175 NI17_15175 dnaX dnaX NI17_22260 NI17_22260 NI17_09045 NI17_09045 GCA_001660385_01199 GCA_001660385_01199 NI17_14180 NI17_14180 NI17_10680 NI17_10680 GCA_001660385_00413 GCA_001660385_00413 GCA_001660385_00394 GCA_001660385_00394 ligA ligA NI17_15660 NI17_15660 GCA_001660385_00177 GCA_001660385_00177 NI17_15625 NI17_15625 GCA_001660385_00175 GCA_001660385_00175 xseA xseA xseB xseB NI17_04050 NI17_04050 NI17_14570 NI17_14570 NI17_18925 NI17_18925 NI17_18010 NI17_18010 NI17_03315 NI17_03315 NI17_02820 NI17_02820 NI17_16580 NI17_16580 GCA_001660385_04945 GCA_001660385_04945 NI17_22115 NI17_22115
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCA_001660385_00841Unannotated protein. (641 aa)
lexAUnannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (256 aa)
NI17_05800Unannotated protein. (725 aa)
NI17_05840Unannotated protein. (596 aa)
GCA_001660385_02811Unannotated protein. (320 aa)
NI17_22550Unannotated protein. (168 aa)
NI17_23010Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (380 aa)
NI17_21105Unannotated protein. (165 aa)
NI17_01345Unannotated protein. (707 aa)
NI17_14325Unannotated protein. (758 aa)
NI17_09215Unannotated protein. (390 aa)
NI17_06880Unannotated protein. (554 aa)
NI17_08970Unannotated protein. (139 aa)
NI17_15175Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (379 aa)
dnaXUnannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (681 aa)
NI17_22260Unannotated protein. (1187 aa)
NI17_09045Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (204 aa)
GCA_001660385_01199Unannotated protein. (323 aa)
NI17_14180Unannotated protein. (326 aa)
NI17_10680Unannotated protein. (694 aa)
GCA_001660385_00413Unannotated protein. (517 aa)
GCA_001660385_00394Unannotated protein. (396 aa)
ligAUnannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (731 aa)
NI17_15660Unannotated protein. (720 aa)
GCA_001660385_00177Unannotated protein. (1121 aa)
NI17_15625Unannotated protein; Belongs to the helicase family. UvrD subfamily. (504 aa)
GCA_001660385_00175Unannotated protein. (434 aa)
xseAUnannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (399 aa)
xseBUnannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa)
NI17_04050Unannotated protein. (720 aa)
NI17_14570Unannotated protein. (605 aa)
NI17_18925Unannotated protein. (250 aa)
NI17_18010Unannotated protein. (696 aa)
NI17_03315Unannotated protein. (716 aa)
NI17_02820Unannotated protein. (280 aa)
NI17_16580Unannotated protein. (1050 aa)
GCA_001660385_04945Unannotated protein. (492 aa)
NI17_22115Unannotated protein. (190 aa)
Your Current Organism:
Thermobifida halotolerans
NCBI taxonomy Id: 483545
Other names: DSM 44931, JCM 16012, KCTC 19123, T. halotolerans, Thermobifida halotolerans Yang et al. 2008, YIM 90462
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