STRINGSTRING
NI17_04050 NI17_04050 NI17_13585 NI17_13585 GCA_001660385_00394 GCA_001660385_00394 GCA_001660385_00413 GCA_001660385_00413 NI17_14075 NI17_14075 NI17_14180 NI17_14180 recO recO NI17_19245 NI17_19245 NI17_01595 NI17_01595 GCA_001660385_00878 GCA_001660385_00878 NI17_04165 NI17_04165 GCA_001660385_01199 GCA_001660385_01199 recR recR NI17_22260 NI17_22260 dnaX dnaX NI17_15255 NI17_15255 NI17_15175 NI17_15175 NI17_08970 NI17_08970 NI17_06415 NI17_06415 NI17_09215 NI17_09215 NI17_06035 NI17_06035 recF recF NI17_23010 NI17_23010 GCA_001660385_02705 GCA_001660385_02705 NI17_23415 NI17_23415 NI17_23420 NI17_23420 GCA_001660385_02811 GCA_001660385_02811 ruvC ruvC ruvA ruvA ruvB ruvB NI17_22115 NI17_22115 NI17_19525 NI17_19525 polA polA priA priA NI17_14570 NI17_14570 NI17_16985 NI17_16985 NI17_18925 NI17_18925 NI17_16290 NI17_16290 NI17_06105 NI17_06105 NI17_01255 NI17_01255 NI17_01125 NI17_01125 GCA_001660385_04616 GCA_001660385_04616 recD2 recD2 NI17_22025 NI17_22025
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NI17_04050Unannotated protein. (720 aa)
NI17_13585Unannotated protein. (753 aa)
GCA_001660385_00394Unannotated protein. (396 aa)
GCA_001660385_00413Unannotated protein. (517 aa)
NI17_14075Unannotated protein. (1210 aa)
NI17_14180Unannotated protein. (326 aa)
recOUnannotated protein; Involved in DNA repair and RecF pathway recombination. (243 aa)
NI17_19245Unannotated protein. (101 aa)
NI17_01595Unannotated protein. (322 aa)
GCA_001660385_00878Unannotated protein. (408 aa)
NI17_04165Unannotated protein. (435 aa)
GCA_001660385_01199Unannotated protein. (323 aa)
recRUnannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
NI17_22260Unannotated protein. (1187 aa)
dnaXUnannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (681 aa)
NI17_15255Unannotated protein. (466 aa)
NI17_15175Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (379 aa)
NI17_08970Unannotated protein. (139 aa)
NI17_06415Unannotated protein. (708 aa)
NI17_09215Unannotated protein. (390 aa)
NI17_06035Unannotated protein. (302 aa)
recFUnannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (378 aa)
NI17_23010Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (380 aa)
GCA_001660385_02705Unannotated protein. (1203 aa)
NI17_23415Unannotated protein. (551 aa)
NI17_23420Unannotated protein. (471 aa)
GCA_001660385_02811Unannotated protein. (320 aa)
ruvCUnannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (182 aa)
ruvAUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
ruvBUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (351 aa)
NI17_22115Unannotated protein. (190 aa)
NI17_19525Unannotated protein. (208 aa)
polAUnannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (918 aa)
priAUnannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (678 aa)
NI17_14570Unannotated protein. (605 aa)
NI17_16985Unannotated protein. (270 aa)
NI17_18925Unannotated protein. (250 aa)
NI17_16290Unannotated protein. (813 aa)
NI17_06105Unannotated protein. (216 aa)
NI17_01255Unannotated protein. (395 aa)
NI17_01125Unannotated protein. (663 aa)
GCA_001660385_04616Unannotated protein. (326 aa)
recD2Unannotated protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (736 aa)
NI17_22025Unannotated protein. (86 aa)
Your Current Organism:
Thermobifida halotolerans
NCBI taxonomy Id: 483545
Other names: DSM 44931, JCM 16012, KCTC 19123, T. halotolerans, Thermobifida halotolerans Yang et al. 2008, YIM 90462
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.