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gltB1 gltB1 pdhD1 pdhD1 KWX78394.1 KWX78394.1 glnA1 glnA1 gltB3 gltB3 pdhD3 pdhD3 KWX77631.1 KWX77631.1 pdhB pdhB pdhA pdhA lipA lipA gcvH gcvH gcvT gcvT gcvPA gcvPA gcvPB gcvPB KWX76669.1 KWX76669.1 lipB lipB KWX74917.1 KWX74917.1 bfmBAB bfmBAB bfmBAA bfmBAA bfmBC bfmBC LPD1 LPD1 acoC acoC KWX74358.1 KWX74358.1 acoA acoA lplJ lplJ GLT1 GLT1 odhB odhB odhA odhA gdh gdh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gltB1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1531 aa)
pdhD1Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
KWX78394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (452 aa)
glnA1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
gltB3Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
pdhD3Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
KWX77631.1Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
pdhB2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
pdhAPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (355 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (301 aa)
gcvHGlycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (130 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (374 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (450 aa)
gcvPBGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
KWX76669.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (240 aa)
KWX74917.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa)
bfmBAB2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
bfmBAA2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
bfmBCDihydrolipoamide dehydrogenase; E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
LPD1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
acoCHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
KWX74358.1Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
acoAAcetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
lplJLipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
GLT1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
odhBDihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (430 aa)
odhA2-oxoglutarate dehydrogenase; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (956 aa)
gdhGlutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (457 aa)
Your Current Organism:
Paenibacillus riograndensis
NCBI taxonomy Id: 483937
Other names: CECT 7330, P. riograndensis, Paenibacillus riograndensis Beneduzi et al. 2010, Paenibacillus sonchi genomovar Oryzarum, Paenibacillus sonchi genomovar Riograndensis, strain SBR5
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