STRINGSTRING
nth nth KWX78808.1 KWX78808.1 eno eno hisB hisB KWX78145.1 KWX78145.1 mutM mutM KWX77644.1 KWX77644.1 KWX77316.1 KWX77316.1 KWX76657.1 KWX76657.1 citB citB uxuA uxuA yagE yagE yagF yagF yoaZ3 yoaZ3 mqnA mqnA aroC3 aroC3 aroB aroB trpB trpB trpA trpA mgsA mgsA murQ murQ yjjA yjjA fabZ-2 fabZ-2 KWX73307.1 KWX73307.1 aroD aroD thrC thrC aroB-2 aroB-2 dapA dapA dapA1 dapA1 ytiB ytiB KWX72148.1 KWX72148.1 KWX70944.1 KWX70944.1 araC araC KWX70949.1 KWX70949.1 KWX70284.1 KWX70284.1 KWX69470.1 KWX69470.1 KWX69479.1 KWX69479.1 aroC1 aroC1 ilvD ilvD KWX80803.1 KWX80803.1 uxaA uxaA KWX80405.1 KWX80405.1 ohyA ohyA KWX80170.1 KWX80170.1 KWX80103.1 KWX80103.1 KWX79977.1 KWX79977.1 hemB hemB pheA pheA fabZ fabZ KWX79763.1 KWX79763.1 leuC leuC leuD leuD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (223 aa)
KWX78808.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (699 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
KWX78145.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (557 aa)
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (280 aa)
KWX77644.1formamidopyrimidine-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPG family. (271 aa)
KWX77316.1Spore coat protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (340 aa)
KWX76657.12-hydroxyglutaryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1429 aa)
citBAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (358 aa)
yagE2-keto-3-deoxy-galactonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (304 aa)
yagFDehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (650 aa)
yoaZ3Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
mqnAABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (286 aa)
aroC3Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (367 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (273 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (140 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (301 aa)
yjjAuroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
fabZ-2hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa)
KWX73307.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (254 aa)
thrCThreonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
aroB-23-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (380 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa)
dapA1Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa)
ytiBCarbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
KWX72148.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
KWX70944.1Dihydrodipicolinate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
araCDihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (590 aa)
KWX70949.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
KWX70284.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
KWX69470.1Secondary thiamine-phosphate synthase enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
KWX69479.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
aroC1Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (355 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (556 aa)
KWX80803.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
uxaAAltronate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
KWX80405.1Secondary thiamine-phosphate synthase enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
ohyAOleate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
KWX80170.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (643 aa)
KWX80103.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
KWX79977.1HemD protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
hemBDelta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (332 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
fabZHypothetical protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
KWX79763.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
Your Current Organism:
Paenibacillus riograndensis
NCBI taxonomy Id: 483937
Other names: CECT 7330, P. riograndensis, Paenibacillus riograndensis Beneduzi et al. 2010, Paenibacillus sonchi genomovar Oryzarum, Paenibacillus sonchi genomovar Riograndensis, strain SBR5
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