STRINGSTRING
KWX74084.1 KWX74084.1 KWX81497.1 KWX81497.1 rluF1 rluF1 uxaC1 uxaC1 galE galE KWX80562.1 KWX80562.1 KWX80594.1 KWX80594.1 glf1 glf1 groEL groEL glmM glmM gmuF gmuF KWX80163.1 KWX80163.1 KWX80191.1 KWX80191.1 hemL2-2 hemL2-2 KWX80013.1 KWX80013.1 gyrB gyrB parC parC KWX79683.1 KWX79683.1 gyrA gyrA gyrB-2 gyrB-2 KWX79208.1 KWX79208.1 bfce bfce pgmB pgmB gpmI gpmI tpiA tpiA hisA hisA truA truA KWX78450.1 KWX78450.1 KWX78257.1 KWX78257.1 KWX78262.1 KWX78262.1 KWX78270.1 KWX78270.1 KWX78296.1 KWX78296.1 KWX78140.1 KWX78140.1 fucU fucU fucI fucI yrpC yrpC xylA7 xylA7 gpmA gpmA KWX77536.1 KWX77536.1 KWX77317.1 KWX77317.1 KWX77344.1 KWX77344.1 dapF dapF rpe rpe KWX77182.1 KWX77182.1 prsA prsA rpiA rpiA queA queA ytzG ytzG murI murI hemL1 hemL1 uxaC3 uxaC3 ylyB ylyB KWX75515.1 KWX75515.1 KWX75186.1 KWX75186.1 pseB pseB nagB nagB nanE nanE tig tig KWX75281.1 KWX75281.1 capD capD KWX75288.1 KWX75288.1 KWX74900.1 KWX74900.1 KWX74902.1 KWX74902.1 deoB deoB KWX74989.1 KWX74989.1 KWX74627.1 KWX74627.1 rluB rluB KWX74691.1 KWX74691.1 trpF trpF fni fni mnaA mnaA pgcA pgcA KWX73799.1 KWX73799.1 pgi pgi alr alr KWX73416.1 KWX73416.1 KWX73067.1 KWX73067.1 rhaA rhaA kduI kduI truB truB topA topA topB topB purE purE nnrD nnrD KWX71702.1 KWX71702.1 KWX70972.1 KWX70972.1 KWX71083.1 KWX71083.1 KWX71086.1 KWX71086.1 rluF3 rluF3 KWX71125.1 KWX71125.1 KWX69343.1 KWX69343.1 araD araD araA2 araA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KWX74084.1Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
KWX81497.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (141 aa)
rluF1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (233 aa)
uxaC1Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
galEUDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (328 aa)
KWX80562.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
KWX80594.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
glf1UDP-galactopyranose mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
groELMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (543 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (446 aa)
gmuFMannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (322 aa)
KWX80163.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (341 aa)
KWX80191.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1765 aa)
hemL2-2Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
KWX80013.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
gyrBDNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (660 aa)
parCDNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (813 aa)
KWX79683.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (848 aa)
gyrB-2DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (636 aa)
KWX79208.1Beta-phosphoglucomutase; Catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
bfceN-acyl-D-glucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man). (406 aa)
pgmBBeta-phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
gpmIPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (259 aa)
KWX78450.1DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa)
KWX78257.1Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (345 aa)
KWX78262.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
KWX78270.1precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KWX78296.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
KWX78140.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
fucUFucose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RbsD / FucU family. (143 aa)
fucISugar isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (588 aa)
yrpCGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (262 aa)
xylA7Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family. (439 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
KWX77536.1Galactose mutarotase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
KWX77317.1dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
KWX77344.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa)
rpeRibulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa)
KWX77182.1Aldose epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
prsAPeptidylprolyl isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (403 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa)
queAS-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (342 aa)
ytzGPseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (254 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (268 aa)
hemL1Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
uxaC3Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ylyBPseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (324 aa)
KWX75515.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
KWX75186.1UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (364 aa)
pseBUDP-N-acetylglucosamine 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (242 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (239 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (446 aa)
KWX75281.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (667 aa)
capDPolysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
KWX75288.1NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
KWX74900.1Hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KWX74902.1AroM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (392 aa)
KWX74989.1Beta-phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
KWX74627.1Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (143 aa)
rluBPseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (252 aa)
KWX74691.1Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (123 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (226 aa)
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (363 aa)
mnaAUDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (384 aa)
pgcAPhosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
KWX73799.1UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (451 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (393 aa)
KWX73416.1Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
KWX73067.1Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (222 aa)
rhaASugar isomerase; Catalyzes the formation of L-rhamnulose from L-rhamnose; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
kduI5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (277 aa)
truBPseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (304 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (698 aa)
topBDNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (712 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa)
nnrDCarbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (552 aa)
KWX71702.1Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
KWX70972.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
KWX71083.1Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
KWX71086.1Sugar phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
rluF3Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (234 aa)
KWX71125.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
KWX69343.16-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
araDCatalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
araA2Arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (474 aa)
Your Current Organism:
Paenibacillus riograndensis
NCBI taxonomy Id: 483937
Other names: CECT 7330, P. riograndensis, Paenibacillus riograndensis Beneduzi et al. 2010, Paenibacillus sonchi genomovar Oryzarum, Paenibacillus sonchi genomovar Riograndensis, strain SBR5
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