(13 nodes) Queuosine metabolic process, and Thiosulfate sulfurtransferase activity network (Sphingobium sp. YBL2)

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	queE	7-cyano-7-deazaguanine reductase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa)
	queC	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (230 aa)
	AJR26112.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
	AJR22791.1	Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. (302 aa)
	queA	S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (344 aa)
	AJR24356.1	Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (223 aa)
	AJR24357.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
	AJR24358.1	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
	AJR26352.1	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
	sseA	3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	queF	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (152 aa)
	AJR26353.1	Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
	tgt	Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (376 aa)

Your Current Organism:

Sphingobium sp. YBL2

NCBI taxonomy Id: 484429
Other names: S. sp. YBL2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJR22791.1	AJR26112.1	TZ53_02410	TZ53_02405	Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.719
AJR22791.1	queC	TZ53_02410	TZ53_02400	Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.689
AJR22791.1	queE	TZ53_02410	TZ53_02395	Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.	7-cyano-7-deazaguanine reductase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.643
AJR24356.1	AJR24357.1	TZ53_12055	TZ53_12065	Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.404
AJR24356.1	queF	TZ53_12055	TZ53_12090	Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.	0.623
AJR24357.1	AJR24356.1	TZ53_12065	TZ53_12055	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.	0.404
AJR24357.1	AJR24358.1	TZ53_12065	TZ53_12070	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.429
AJR24357.1	AJR26352.1	TZ53_12065	TZ53_12075	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436
AJR24357.1	sseA	TZ53_12065	TZ53_12080	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436
AJR24358.1	AJR24357.1	TZ53_12070	TZ53_12065	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.429
AJR24358.1	AJR26352.1	TZ53_12070	TZ53_12075	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.861
AJR24358.1	queF	TZ53_12070	TZ53_12090	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.	0.626
AJR24358.1	sseA	TZ53_12070	TZ53_12080	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.861
AJR26112.1	AJR22791.1	TZ53_02405	TZ53_02410	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.	0.719
AJR26112.1	queC	TZ53_02405	TZ53_02400	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.	0.721
AJR26112.1	queE	TZ53_02405	TZ53_02395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-cyano-7-deazaguanine reductase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.	0.714
AJR26352.1	AJR24357.1	TZ53_12075	TZ53_12065	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.436
AJR26352.1	AJR24358.1	TZ53_12075	TZ53_12070	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.861
AJR26352.1	queF	TZ53_12075	TZ53_12090	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.	0.626
AJR26352.1	sseA	TZ53_12075	TZ53_12080	Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994