STRINGSTRING
metAA metAA AJR22476.1 AJR22476.1 AJR22545.1 AJR22545.1 AJR26071.1 AJR26071.1 thrB thrB leuD leuD leuC leuC nadA nadA lysA lysA argH argH AJR22649.1 AJR22649.1 AJR22659.1 AJR22659.1 AJR22661.1 AJR22661.1 AJR26094.1 AJR26094.1 AJR22701.1 AJR22701.1 AJR22707.1 AJR22707.1 AJR22708.1 AJR22708.1 AJR22726.1 AJR22726.1 AJR22731.1 AJR22731.1 AJR22755.1 AJR22755.1 AJR22792.1 AJR22792.1 argD argD dapA dapA kdsA kdsA proA proA AJR22934.1 AJR22934.1 AJR23022.1 AJR23022.1 panC panC aroE aroE AJR23157.1 AJR23157.1 AJR23184.1 AJR23184.1 ilvD ilvD AJR23261.1 AJR23261.1 AJR23384.1 AJR23384.1 AJR23464.1 AJR23464.1 AJR23540.1 AJR23540.1 mtnA mtnA mtnK mtnK mtnC mtnC mtnD mtnD mtnB mtnB AJR23592.1 AJR23592.1 putA putA AJR23644.1 AJR23644.1 AJR23645.1 AJR23645.1 AJR23691.1 AJR23691.1 AJR23775.1 AJR23775.1 AJR23940.1 AJR23940.1 AJR23962.1 AJR23962.1 AJR23966.1 AJR23966.1 AJR23968.1 AJR23968.1 AJR24019.1 AJR24019.1 hisC hisC metX metX AJR24046.1 AJR24046.1 hisD hisD hisG hisG bioD bioD AJR24088.1 AJR24088.1 dapD dapD AJR24101.1 AJR24101.1 AJR24102.1 AJR24102.1 AJR24103.1 AJR24103.1 AJR24110.1 AJR24110.1 aroC aroC AJR24134.1 AJR24134.1 AJR24136.1 AJR24136.1 AJR24213.1 AJR24213.1 plsX plsX fabH fabH argG argG AJR24305.1 AJR24305.1 AJR24306.1 AJR24306.1 aroQ aroQ acpS acpS AJR24347.1 AJR24347.1 folD folD argB argB AJR24446.1 AJR24446.1 AJR24518.1 AJR24518.1 dapE dapE AJR24620.1 AJR24620.1 proB proB AJR24718.1 AJR24718.1 proC proC panB panB AJR24817.1 AJR24817.1 fabZ fabZ aroB aroB aroK aroK accA accA AJR24856.1 AJR24856.1 trpC trpC trpD trpD hisE hisE hisF hisF hisA hisA hisH hisH hisB hisB AJR24921.1 AJR24921.1 AJR24923.1 AJR24923.1 AJR24933.1 AJR24933.1 AJR24960.1 AJR24960.1 AJR26441.1 AJR26441.1 acpP acpP AJR24982.1 AJR24982.1 trpE trpE leuB leuB metZ metZ AJR25071.1 AJR25071.1 carA carA carB carB AJR26463.1 AJR26463.1 ilvC ilvC AJR25150.1 AJR25150.1 AJR25153.1 AJR25153.1 AJR26466.1 AJR26466.1 AJR25198.1 AJR25198.1 AJR25206.1 AJR25206.1 glyA glyA hisI hisI aroA aroA AJR25242.1 AJR25242.1 accD accD trpA trpA trpB trpB trpF trpF AJR25279.1 AJR25279.1 AJR25338.1 AJR25338.1 AJR25379.1 AJR25379.1 AJR25416.1 AJR25416.1 argJ argJ lipA lipA asd asd AJR25507.1 AJR25507.1 bioB bioB AJR25514.1 AJR25514.1 AJR25559.1 AJR25559.1 AJR25611.1 AJR25611.1 glnA glnA dapB dapB AJR25707.1 AJR25707.1 AJR25724.1 AJR25724.1 AJR25821.1 AJR25821.1 serS serS argC argC AJR26544.1 AJR26544.1 AJR25911.1 AJR25911.1 AJR26007.1 AJR26007.1 dapF dapF AJR26047.1 AJR26047.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (308 aa)
AJR22476.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
AJR22545.1Phosphopantetheine-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
AJR26071.1Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
thrBSerine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (325 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (484 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (426 aa)
argHArgininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AJR22649.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AJR22659.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (311 aa)
AJR22661.15-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa)
AJR26094.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (573 aa)
AJR22701.1Protein usg; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AJR22707.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
AJR22708.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
AJR22726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AJR22731.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
AJR22755.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
AJR22792.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (309 aa)
argDAcetylornithine aminotransferase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (275 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa)
AJR22934.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
AJR23022.1Carbamoyl phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa)
AJR23157.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AJR23184.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (617 aa)
AJR23261.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
AJR23384.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
AJR23464.1Cobalamin biosynthesis protein CobG; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AJR23540.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (354 aa)
mtnKMethylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (419 aa)
mtnCEnolase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (227 aa)
mtnDCupin; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (183 aa)
mtnBMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (208 aa)
AJR23592.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
putATranscriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1200 aa)
AJR23644.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AJR23645.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (596 aa)
AJR23691.1Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
AJR23775.1Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (100 aa)
AJR23940.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
AJR23962.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AJR23966.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1014 aa)
AJR23968.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1016 aa)
AJR24019.1Cyclohexadienyl dehydrogenase; Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
hisCHistidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (365 aa)
metXHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (383 aa)
AJR24046.1Cysteine biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa)
hisGATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (220 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (205 aa)
AJR24088.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (279 aa)
AJR24101.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (390 aa)
AJR24102.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
AJR24103.1tRNA synthetase class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
AJR24110.1enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa)
AJR24134.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1512 aa)
AJR24136.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
AJR24213.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (600 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (322 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
AJR24305.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
AJR24306.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (133 aa)
AJR24347.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (305 aa)
AJR24446.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
AJR24518.1Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (380 aa)
AJR24620.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (376 aa)
AJR24718.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (290 aa)
AJR24817.1Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (237 aa)
fabZ3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (160 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (370 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (182 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa)
AJR24856.1methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (263 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa)
hisACatalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AJR24921.1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
AJR24923.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
AJR24933.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
AJR24960.1Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
AJR26441.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
AJR24982.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (419 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (500 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (348 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (402 aa)
AJR25071.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
carACarbamoyl-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (387 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1111 aa)
AJR26463.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
AJR25150.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
AJR25153.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AJR26466.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AJR25198.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AJR25206.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (439 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (123 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (446 aa)
AJR25242.1Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (440 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (276 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (413 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (214 aa)
AJR25279.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
AJR25338.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AJR25379.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AJR25416.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
argJArginine biosynthesis protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa)
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (327 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
AJR25507.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (348 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (332 aa)
AJR25514.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
AJR25559.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AJR25611.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (254 aa)
AJR25707.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AJR25724.1Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (175 aa)
AJR25821.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (314 aa)
AJR26544.1NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AJR25911.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AJR26007.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (266 aa)
AJR26047.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
Your Current Organism:
Sphingobium sp. YBL2
NCBI taxonomy Id: 484429
Other names: S. sp. YBL2
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