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UFO1_2177 UFO1_2177 rimO rimO miaB miaB UFO1_2070 UFO1_2070 ispH ispH UFO1_1820 UFO1_1820 rlmN rlmN UFO1_1744 UFO1_1744 UFO1_1724 UFO1_1724 UFO1_1645 UFO1_1645 moaA moaA UFO1_1541 UFO1_1541 UFO1_1539 UFO1_1539 nth nth UFO1_1385 UFO1_1385 UFO1_1353 UFO1_1353 thiC thiC mqnC mqnC mqnE mqnE UFO1_1251 UFO1_1251 UFO1_1247 UFO1_1247 UFO1_1135 UFO1_1135 UFO1_1127 UFO1_1127 UFO1_1062 UFO1_1062 leuC-3 leuC-3 leuC-2 leuC-2 UFO1_0827 UFO1_0827 UFO1_0730 UFO1_0730 nuoB nuoB UFO1_0707 UFO1_0707 UFO1_0648 UFO1_0648 UFO1_0611 UFO1_0611 UFO1_0430 UFO1_0430 UFO1_0422 UFO1_0422 queE queE rlmN-2 rlmN-2 UFO1_2407 UFO1_2407 ispG ispG UFO1_2614 UFO1_2614 UFO1_2675 UFO1_2675 UFO1_2705 UFO1_2705 UFO1_2713 UFO1_2713 UFO1_2762 UFO1_2762 UFO1_2768 UFO1_2768 UFO1_2769 UFO1_2769 UFO1_2772 UFO1_2772 UFO1_2774 UFO1_2774 nifH-2 nifH-2 nifH-3 nifH-3 rnfB rnfB rnfC rnfC UFO1_3066 UFO1_3066 UFO1_3109 UFO1_3109 UFO1_3185 UFO1_3185 UFO1_3278 UFO1_3278 UFO1_3323 UFO1_3323 nifH nifH hcp hcp leuC leuC UFO1_0153 UFO1_0153 nadA nadA UFO1_0264 UFO1_0264 bioB bioB bioB-2 bioB-2 UFO1_0398 UFO1_0398 UFO1_0415 UFO1_0415 UFO1_2284 UFO1_2284 mqnE-2 mqnE-2 UFO1_4436 UFO1_4436 UFO1_4022 UFO1_4022 UFO1_3967 UFO1_3967 UFO1_3966 UFO1_3966 nifH-4 nifH-4 UFO1_3797 UFO1_3797 UFO1_3587 UFO1_3587 hcp-2 hcp-2 UFO1_3514 UFO1_3514 UFO1_3422 UFO1_3422 UFO1_3415 UFO1_3415
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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UFO1_2177UPF0313 protein ygiQ; SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Uncharacterized protein family UPF0313; KEGG: radical SAM protein; HAMAP : UPF0313 protein ygiQ; PFAM: Radical SAM domain protein, Radical SAM domain protein, Uncharacterized protein family UPF0313, C-terminal. (640 aa)
rimORibosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (443 aa)
miaB(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (458 aa)
UFO1_2070KEGG: radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (353 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (656 aa)
UFO1_1820Formate dehydrogenase, alpha subunit; SMART: molybdopterin oxidoreductase Fe4S4 region; TIGRFAM: formate dehydrogenase, alpha subunit; KEGG: fdhA, formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase, molybdopterin dinucleotide-binding region, molybdopterin oxidoreductase Fe4S4 region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (678 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (352 aa)
UFO1_17443-isopropylmalate dehydratase; KEGG: aconitase A; PFAM: aconitate hydratase domain-containing protein. (798 aa)
UFO1_1724PFAM: Radical SAM domain protein; KEGG: radical SAM domain-containing protein. (258 aa)
UFO1_1645TIGRFAM: lysine-2,3-aminomutase, lysine 2,3-aminomutase YodO family protein; KEGG: lysine 2,3-aminomutase YodO family protein; PFAM: Lysine-2,3-aminomutase, C-terminal domain, Radical SAM domain protein. (428 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (323 aa)
UFO1_1541Nitrate reductase, alpha subunit; SMART: molybdopterin oxidoreductase Fe4S4 region; TIGRFAM: nitrate reductase, alpha subunit; KEGG: narG, nitrate reductase subunit alpha; PFAM: molybdopterin oxidoreductase, molybdopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1229 aa)
UFO1_1539KEGG: sulfite reductase subunit C; TIGRFAM: sulfite reductase, subunit C; PFAM: nitrite and sulfite reductase 4Fe-4S region, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. (315 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (210 aa)
UFO1_1385PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit, Soluble ligand binding domain-containing protein, NADH ubiquinone oxidoreductase, F subunit, iron sulfur binding protein; KEGG: NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulfur binding protein. (432 aa)
UFO1_1353SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, thiamine pyrophosphate TPP-binding domain-containing protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. (1180 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (432 aa)
mqnCMenaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (344 aa)
mqnEPutative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (367 aa)
UFO1_1251TIGRFAM: [FeFe]-hydrogenase maturation HydE, radical SAM; PFAM: Radical SAM domain protein, biotin and thiamin synthesis associated protein; KEGG: Radical SAM domain-containing protein; SMART: Elongator protein 3/MiaB/NifB, biotin and thiamin synthesis associated protein. (345 aa)
UFO1_1247TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit. (410 aa)
UFO1_1135PFAM: 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein; KEGG: 4Fe-4S ferredoxin. (104 aa)
UFO1_1127PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit, RnfC Barrel sandwich hybrid domain, Soluble ligand binding domain-containing protein; KEGG: respiratory-chain NADH dehydrogenase domain 51 kDa subunit. (444 aa)
UFO1_1062SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein. (1181 aa)
leuC-33-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (418 aa)
UFO1_0827KEGG: aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain-containing protein. (640 aa)
UFO1_0730PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; KEGG: nuoI, proton-translocating NADH-ubiquinone oxidoreductase, 23 kd, chain i. (158 aa)
nuoBNAD(P)H-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (171 aa)
UFO1_0707PFAM: protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein; KEGG: Fe-S oxidoreductase. (408 aa)
UFO1_0648TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; KEGG: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (652 aa)
UFO1_0611KEGG: radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (330 aa)
UFO1_0430Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (240 aa)
UFO1_0422PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; KEGG: 4Fe-4S ferredoxin. (426 aa)
queE7-carboxy-7-deazaguanine synthase-like; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (244 aa)
rlmN-2Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (351 aa)
UFO1_24074Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (54 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (364 aa)
UFO1_2614TIGRFAM: Conserved hypothetical protein CHP01212; PFAM: Radical SAM domain protein; KEGG: hypothetical protein; SMART: Elongator protein 3/MiaB/NifB. (313 aa)
UFO1_2675TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit. (366 aa)
UFO1_2705TIGRFAM: RNA modification enzyme, MiaB family, MiaB-like tRNA modifying enzyme; PFAM: protein of unknown function UPF0004, Radical SAM domain protein; KEGG: yqeV, putative MiaB-like tRNA modifying enzyme family protein; SMART: Elongator protein 3/MiaB/NifB. (435 aa)
UFO1_2713Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (376 aa)
UFO1_2762PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein; KEGG: Ni,Fe-hydrogenase III small subunit. (241 aa)
UFO1_2768TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; KEGG: L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain. (293 aa)
UFO1_2769TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; KEGG: sdhB2, iron-sulfur-dependent L-serine dehydratase subunit beta; PFAM: serine dehydratase beta chain, amino acid-binding ACT domain-containing protein. (220 aa)
UFO1_2772CoB--CoM heterodisulfide reductase; KEGG: hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein. (439 aa)
UFO1_2774TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; KEGG: carbon monoxide dehydrogenase beta subunit; PFAM: Prismane. (708 aa)
nifH-2Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (291 aa)
nifH-3Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (291 aa)
rnfBElectron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (290 aa)
rnfCElectron transport complex protein rnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (440 aa)
UFO1_3066TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; KEGG: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (281 aa)
UFO1_3109PFAM: Lactate utilization protein B/C, protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein; KEGG: Lactate utilization protein B/C. (723 aa)
UFO1_3185KEGG: hypothetical protein. (101 aa)
UFO1_3278KEGG: hypothetical protein; TIGRFAM: DNA metabolism protein, putative; PFAM: Domain of unknown function DUF4130. (267 aa)
UFO1_3323Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (163 aa)
nifHNitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (273 aa)
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (432 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa)
UFO1_0153KEGG: (Fe-S)-binding protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Lactate utilization protein B/C, 4Fe-4S ferredoxin, iron-sulpur binding domain-containing protein, 4Fe-4S binding protein, C-terminal. (473 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (301 aa)
UFO1_0264SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein. (1174 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (330 aa)
bioB-2Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)
UFO1_0398TIGRFAM: glycyl-radical enzyme activating protein family; KEGG: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein. (300 aa)
UFO1_0415A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (359 aa)
UFO1_2284KEGG: hypothetical protein. (217 aa)
mqnE-2Putative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (361 aa)
UFO1_4436KEGG: ferredoxin--nitrite reductase; PFAM: nitrite and sulfite reductase 4Fe-4S region, nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. (536 aa)
UFO1_4022KEGG: glpC, putative anaerobic glycerol-3-phosphate dehydrogenase subunit C; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (398 aa)
UFO1_3967Hypothetical protein; KEGG: 4-hydroxyphenylacetate decarboxylase regulatory subunit. (88 aa)
UFO1_3966TIGRFAM: glycyl-radical enzyme activating protein family; KEGG: hpdA, 4-hydroxyphenylacetate decarboxylase activating subunit; PFAM: Radical SAM domain protein. (311 aa)
nifH-4Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (275 aa)
UFO1_3797PFAM: aldehyde ferredoxin oxidoreductase, Aldehyde ferredoxin oxidoreductase; KEGG: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (573 aa)
UFO1_3587PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; KEGG: 2-oxoglutarate ferredoxin oxidoreductase subunit delta. (67 aa)
hcp-2Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (571 aa)
UFO1_3514TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; KEGG: tartrate dehydratase subunit alpha; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (299 aa)
UFO1_3422KEGG: hypothetical protein. (216 aa)
UFO1_3415PFAM: Radical SAM domain protein; KEGG: radical SAM domain-containing protein. (227 aa)
Your Current Organism:
Pelosinus sp. UFO1
NCBI taxonomy Id: 484770
Other names: P. sp. UFO1, Pelosinus lilaceae
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