STRINGSTRING
UFO1_0042 UFO1_0042 UFO1_0043 UFO1_0043 UFO1_0196 UFO1_0196 UFO1_0207 UFO1_0207 UFO1_0239 UFO1_0239 UFO1_0264 UFO1_0264 UFO1_0327 UFO1_0327 UFO1_0400 UFO1_0400 UFO1_0431 UFO1_0431 UFO1_0449 UFO1_0449 UFO1_0959 UFO1_0959 UFO1_0960 UFO1_0960 UFO1_0982 UFO1_0982 UFO1_0992 UFO1_0992 fumC fumC UFO1_1000 UFO1_1000 UFO1_1001 UFO1_1001 UFO1_1062 UFO1_1062 UFO1_1122 UFO1_1122 UFO1_1201 UFO1_1201 UFO1_1353 UFO1_1353 UFO1_1497 UFO1_1497 UFO1_1563 UFO1_1563 UFO1_1914 UFO1_1914 UFO1_2006 UFO1_2006 ackA ackA pckA pckA leuA leuA UFO1_2345 UFO1_2345 UFO1_2346 UFO1_2346 UFO1_2348 UFO1_2348 pckA-2 pckA-2 UFO1_2729 UFO1_2729 UFO1_2732 UFO1_2732 UFO1_2963 UFO1_2963 UFO1_3045 UFO1_3045 UFO1_3049 UFO1_3049 UFO1_3065 UFO1_3065 UFO1_3066 UFO1_3066 UFO1_3093 UFO1_3093 UFO1_3173 UFO1_3173 UFO1_3232 UFO1_3232 UFO1_3233 UFO1_3233 UFO1_3270 UFO1_3270 UFO1_3282 UFO1_3282 UFO1_3314 UFO1_3314 UFO1_3315 UFO1_3315 UFO1_3367 UFO1_3367 UFO1_3420 UFO1_3420 UFO1_3585 UFO1_3585 UFO1_3586 UFO1_3586 UFO1_3616 UFO1_3616 UFO1_3627 UFO1_3627 UFO1_3686 UFO1_3686 UFO1_3688 UFO1_3688 UFO1_3851 UFO1_3851 UFO1_3852 UFO1_3852 UFO1_4011 UFO1_4011 UFO1_4020 UFO1_4020 UFO1_4039 UFO1_4039 mdh mdh UFO1_4066 UFO1_4066 leuA-2 leuA-2 UFO1_4403 UFO1_4403
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UFO1_0042KEGG: nifV, homocitrate synthase; PFAM: pyruvate carboxyltransferase. (370 aa)
UFO1_0043KEGG: nifV, homocitrate synthase; PFAM: pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (284 aa)
UFO1_0196PFAM: Glyoxalase-like domain; KEGG: glyoxalase/bleomycin resistance protein/dioxygenase. (125 aa)
UFO1_0207TIGRFAM: acetyl-CoA acetyltransferase; KEGG: atoB, acetyl-CoA acetyltransferase; PFAM: Thiolase domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
UFO1_0239Methylglyoxal reductase (NADPH-dependent); KEGG: 2,5-diketo-D-gluconic acid reductase; PFAM: NADP-dependent oxidoreductase domain. (280 aa)
UFO1_0264SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein. (1174 aa)
UFO1_0327PFAM: Glyoxalase-like domain; KEGG: lactoylglutathione lyase-like lyase. (125 aa)
UFO1_0400KEGG: aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (482 aa)
UFO1_0431TIGRFAM: formate acetyltransferase; KEGG: pflB, putative pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL, formate C-acetyltransferase glycine radical. (743 aa)
UFO1_0449PFAM: Protein of unknown function DUF2088; KEGG: hypothetical protein. (421 aa)
UFO1_0959TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; KEGG: 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (287 aa)
UFO1_0960TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase. (581 aa)
UFO1_0982PFAM: Glyoxalase-like domain; KEGG: Glyoxalase/bleomycin resistance protein/dioxygenase. (120 aa)
UFO1_0992PFAM: Protein of unknown function DUF2088; KEGG: hypothetical protein. (431 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
UFO1_10003-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (356 aa)
UFO1_10012-oxoglutarate synthase; KEGG: thiamine pyrophosphate protein domain-containing protein; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (250 aa)
UFO1_1062SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein. (1181 aa)
UFO1_1122Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (218 aa)
UFO1_1201Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (385 aa)
UFO1_1353SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, thiamine pyrophosphate TPP-binding domain-containing protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. (1180 aa)
UFO1_1497KEGG: pyruvate carboxyltransferase; PFAM: carboxylase region-containing protein, pyruvate carboxyltransferase. (451 aa)
UFO1_1563TIGRFAM: pyruvate kinase; KEGG: pyruvate kinase; PFAM: Pyruvate kinase barrel, PEP-utilising protein mobile region, Pyruvate kinase -like protein; Belongs to the pyruvate kinase family. (584 aa)
UFO1_1914KEGG: beta-lactamase; PFAM: beta-lactamase domain protein; SMART: beta-lactamase domain protein. (206 aa)
UFO1_2006TIGRFAM: dihydrolipoamide dehydrogenase; KEGG: lpd, dihydrolipoyl dehydrogenase Lpd; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (468 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (525 aa)
leuATranscriptional regulator with only HTH domain, AraC family; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (662 aa)
UFO1_23452-oxoglutarate synthase; KEGG: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (250 aa)
UFO1_2346KEGG: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Transketolase domain-containing protein. (356 aa)
UFO1_2348Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (191 aa)
pckA-2Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (521 aa)
UFO1_2729acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (464 aa)
UFO1_2732acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa)
UFO1_2963TIGRFAM: succinate CoA transferase; KEGG: succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase C-terminal domain, acetyl-CoA hydrolase/transferase. (501 aa)
UFO1_3045TIGRFAM: succinate CoA transferase; KEGG: succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase C-terminal domain, acetyl-CoA hydrolase/transferase. (501 aa)
UFO1_3049Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (385 aa)
UFO1_3065TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; KEGG: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region. (185 aa)
UFO1_3066TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; KEGG: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (281 aa)
UFO1_3093TIGRFAM: acetyl-CoA acetyltransferase; KEGG: acetyl-CoA acetyltransferase; PFAM: Thiolase domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
UFO1_3173KEGG: coenzyme A transferase; PFAM: coenzyme A transferase; SMART: coenzyme A transferase; Belongs to the 3-oxoacid CoA-transferase family. (523 aa)
UFO1_3232KEGG: 2-oxoglutarate synthase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (272 aa)
UFO1_32332-oxoglutarate synthase; KEGG: PorA, pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Transketolase domain-containing protein. (375 aa)
UFO1_3270Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (376 aa)
UFO1_3282TIGRFAM: acetyl-CoA acetyltransferase; KEGG: acetyl-CoA acetyltransferase; PFAM: Thiolase domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. (379 aa)
UFO1_3314TIGRFAM: acetyl-CoA acetyltransferase; KEGG: atoB, acetyl-CoA acetyltransferase; PFAM: Thiolase domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
UFO1_3315KEGG: coenzyme A transferase; PFAM: coenzyme A transferase; SMART: coenzyme A transferase; Belongs to the 3-oxoacid CoA-transferase family. (515 aa)
UFO1_3367TIGRFAM: phosphate acetyltransferase; KEGG: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (324 aa)
UFO1_3420PFAM: Glyoxalase-like domain; KEGG: glxI, bleomycin resistance protein. (128 aa)
UFO1_35852-oxoglutarate synthase; KEGG: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein. (247 aa)
UFO1_35863-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Transketolase domain-containing protein. (355 aa)
UFO1_3616PFAM: Protein of unknown function DUF2088; KEGG: hypothetical protein. (429 aa)
UFO1_3627PFAM: Glyoxalase-like domain; KEGG: glyoxalase/bleomycin resistance protein/dioxygenase. (129 aa)
UFO1_3686PFAM: malic protein NAD-binding protein, malic protein domain protein; KEGG: sfcA, malate dehydrogenase; SMART: malic protein NAD-binding protein. (413 aa)
UFO1_3688TIGRFAM: acetyl-CoA acetyltransferase; KEGG: thiolase; PFAM: Thiolase domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
UFO1_3851KEGG: nifV, homocitrate synthase; PFAM: pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (287 aa)
UFO1_3852KEGG: nifV, homocitrate synthase; PFAM: pyruvate carboxyltransferase. (362 aa)
UFO1_4011TIGRFAM: pyruvate kinase; KEGG: pyruvate kinase; PFAM: Pyruvate kinase barrel, Pyruvate kinase -like protein, PEP-utilising protein mobile region; Belongs to the pyruvate kinase family. (584 aa)
UFO1_4020TIGRFAM: pyruvate kinase; KEGG: pyruvate kinase; PFAM: Pyruvate kinase barrel, PEP-utilising protein mobile region, Pyruvate kinase -like protein; Belongs to the pyruvate kinase family. (584 aa)
UFO1_4039TIGRFAM: phosphate acetyltransferase; KEGG: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (332 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
UFO1_4066Pyruvate carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding protein, Carbamoyl-phosphate synthetase large chain domain protein, biotin carboxylase domain protein; KEGG: accC, putative acetyl-CoA carboxylase, biotin carboxylase; SMART: biotin carboxylase domain protein. (460 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa)
UFO1_4403TIGRFAM: pyruvate, phosphate dikinase; KEGG: ppdK, pyruvate phosphate dikinase; PFAM: PEP-utilizing protein, pyruvate phosphate dikinase PEP/pyruvate-binding protein, PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (885 aa)
Your Current Organism:
Pelosinus sp. UFO1
NCBI taxonomy Id: 484770
Other names: P. sp. UFO1, Pelosinus lilaceae
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