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Phep_4193 Phep_4193 Phep_0028 Phep_0028 Phep_0091 Phep_0091 Phep_0144 Phep_0144 Phep_0172 Phep_0172 Phep_0206 Phep_0206 Phep_0218 Phep_0218 fabH fabH lipB lipB Phep_0278 Phep_0278 Phep_0401 Phep_0401 lnt lnt Phep_0550 Phep_0550 Phep_0637 Phep_0637 Phep_0801 Phep_0801 Phep_0834 Phep_0834 Phep_0858 Phep_0858 Phep_0900 Phep_0900 Phep_1138 Phep_1138 plsY plsY Phep_1339 Phep_1339 Phep_1417 Phep_1417 Phep_1492 Phep_1492 Phep_1567 Phep_1567 Phep_1572 Phep_1572 Phep_1611 Phep_1611 Phep_1633 Phep_1633 Phep_1640 Phep_1640 Phep_1641 Phep_1641 Phep_1642 Phep_1642 Phep_1791 Phep_1791 Phep_1872 Phep_1872 metXA metXA Phep_1980 Phep_1980 Phep_2018 Phep_2018 Phep_2023 Phep_2023 Phep_2034 Phep_2034 Phep_2053 Phep_2053 Phep_2172 Phep_2172 Phep_2196 Phep_2196 fabV fabV Phep_2363 Phep_2363 Phep_2432 Phep_2432 Phep_2438 Phep_2438 fabH-2 fabH-2 Phep_2511 Phep_2511 Phep_2579 Phep_2579 Phep_2612 Phep_2612 Phep_2901 Phep_2901 Phep_2923 Phep_2923 Phep_3033 Phep_3033 Phep_3136 Phep_3136 metAA metAA Phep_3189 Phep_3189 Phep_3321 Phep_3321 Phep_3336 Phep_3336 Phep_3356 Phep_3356 Phep_3424 Phep_3424 Phep_3427 Phep_3427 Phep_3439 Phep_3439 tsaD tsaD Phep_3620 Phep_3620 Phep_3715 Phep_3715 Phep_3723 Phep_3723 Phep_3731 Phep_3731 plsX plsX fabH-3 fabH-3 Phep_3900 Phep_3900 Phep_3922 Phep_3922 Phep_3937 Phep_3937 Phep_4046 Phep_4046 Phep_4148 Phep_4148 aat aat Phep_4210 Phep_4210 Phep_4278 Phep_4278 fabZ fabZ lpxD lpxD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Phep_41933-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa)
Phep_0028PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III. (360 aa)
Phep_0091GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (164 aa)
Phep_0144Hypothetical protein. (359 aa)
Phep_0172Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: e3 binding domain; Biotin-requiring enzyme; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form. (551 aa)
Phep_0206Conserved hypothetical protein. (605 aa)
Phep_0218PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (249 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (348 aa)
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (231 aa)
Phep_0278PFAM: Glutamine cyclotransferase. (364 aa)
Phep_0401Hypothetical protein. (325 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (539 aa)
Phep_0550PFAM: Bacterial transferase hexapeptide (three repeats). (193 aa)
Phep_0637GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (139 aa)
Phep_0801Methicillin resistance protein; PFAM: FemAB family. (373 aa)
Phep_0834PFAM: Acyltransferase. (583 aa)
Phep_0858PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (272 aa)
Phep_0900GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (188 aa)
Phep_1138Enoyl-(acyl-carrier-protein) reductase (NADH). (272 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (215 aa)
Phep_1339Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (270 aa)
Phep_1417GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (141 aa)
Phep_1492Hypothetical protein. (86 aa)
Phep_1567Hypothetical protein. (391 aa)
Phep_1572Conserved hypothetical protein. (372 aa)
Phep_16113-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa)
Phep_1633GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (147 aa)
Phep_1640PFAM: Beta-ketoacyl synthase, C-terminal domain; Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (425 aa)
Phep_1641Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; PFAM: FabA-like domain. (148 aa)
Phep_1642PFAM: Chalcone and stilbene synthases, C-terminal domain; Chalcone and stilbene synthases, N-terminal domain. (350 aa)
Phep_1791GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (192 aa)
Phep_1872Catalytic domain of components of various dehydrogenase complexes; PFAM: Biotin-requiring enzyme; e3 binding domain; 2-oxoacid dehydrogenases acyltransferase (catalytic domain). (440 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (352 aa)
Phep_1980PFAM: Acyltransferase family. (352 aa)
Phep_2018PFAM: Acyl transferase domain; Cytochrome P450. (738 aa)
Phep_2023PFAM: Acyltransferase family. (363 aa)
Phep_2034Amino acid adenylation domain protein; PFAM: Aminotransferase class-III; AMP-binding enzyme; Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; TIGRFAM: amino acid adenylation domain. (2176 aa)
Phep_2053PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (428 aa)
Phep_2172PFAM: Bacterial lipid A biosynthesis acyltransferase. (293 aa)
Phep_2196Conserved hypothetical protein. (372 aa)
fabVTrans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa)
Phep_2363Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. (270 aa)
Phep_2432GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (186 aa)
Phep_2438PFAM: Family of unknown function (DUF470); Family of unknown function (DUF471); Family of unknown function (DUF472); TIGRFAM: conserved hypothetical protein. (862 aa)
fabH-23-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (337 aa)
Phep_2511Hypothetical protein. (330 aa)
Phep_2579PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (244 aa)
Phep_2612GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (148 aa)
Phep_2901acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Phep_2923GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (158 aa)
Phep_3033GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (287 aa)
Phep_3136PFAM: Acyltransferase family. (361 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (312 aa)
Phep_3189GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (145 aa)
Phep_33218-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II. (413 aa)
Phep_3336GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (143 aa)
Phep_3356Putative acetyltransferase. (205 aa)
Phep_3424Pyruvate carboxyltransferase; PFAM: HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. (387 aa)
Phep_3427Pyruvate carboxyltransferase; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. (505 aa)
Phep_3439Acetyltransferase. (102 aa)
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (333 aa)
Phep_3620Hypothetical protein. (206 aa)
Phep_37152-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (412 aa)
Phep_3723acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Phep_3731Gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. (571 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (312 aa)
fabH-33-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)
Phep_3900PFAM: Acyltransferase family. (423 aa)
Phep_3922Hypothetical protein. (192 aa)
Phep_3937GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family. (181 aa)
Phep_4046PFAM: Bacterial transferase hexapeptide (three repeats). (182 aa)
Phep_4148PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (292 aa)
aatleucyl/phenylalanyl-tRNA/protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (211 aa)
Phep_4210Hypothetical protein. (233 aa)
Phep_4278acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (261 aa)
fabZUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (469 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (357 aa)
Your Current Organism:
Pedobacter heparinus
NCBI taxonomy Id: 485917
Other names: P. heparinus DSM 2366, Pedobacter heparinus DSM 2366, Pedobacter heparinus IFO 12017, Pedobacter heparinus LMG 10339, Pedobacter heparinus str. DSM 2366, Pedobacter heparinus strain DSM 2366
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