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Phep_3517 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (632 aa) | ||||
Phep_2034 | Amino acid adenylation domain protein; PFAM: Aminotransferase class-III; AMP-binding enzyme; Acyl transferase domain; Beta-ketoacyl synthase, N-terminal domain; TIGRFAM: amino acid adenylation domain. (2176 aa) | ||||
Phep_2033 | Amino acid adenylation domain protein; PFAM: Condensation domain; AMP-binding enzyme; Methyltransferase domain; TIGRFAM: amino acid adenylation domain. (1740 aa) |