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| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa) |
| | Phep_0172 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: e3 binding domain; Biotin-requiring enzyme; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form. (551 aa) |
| | Phep_0179 | Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (337 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (261 aa) |
| | Phep_0210 | TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (209 aa) |
| | Phep_0211 | PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; FAD binding domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. (659 aa) |
| | Phep_0212 | PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (256 aa) |
| | Phep_0261 | HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: ACT domain; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like. (432 aa) |
| | pgi | PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (548 aa) |
| | Phep_0382 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (256 aa) |
| | comB | PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (239 aa) |
| | Phep_0497 | 3-carboxymuconate cyclase-like protein; PFAM: Domain of unknown function (DUF2394). (372 aa) |
| | Phep_0508 | Ferredoxin; PFAM: Oxidoreductase NAD-binding domain; Oxidoreductase FAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain. (350 aa) |
| | Phep_0522 | PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family. (312 aa) |
| | Phep_0539 | Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. (336 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | Phep_0582 | PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. (313 aa) |
| | Phep_0639 | PFAM: Carboxyl transferase domain. (513 aa) |
| | Phep_0660 | PFAM: Aconitase family (aconitate hydratase); Aconitase C-terminal domain; TIGRFAM: aconitate hydratase, mitochondrial. (758 aa) |
| | Phep_0679 | PFAM: ROK family. (325 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa) |
| | Phep_0734 | PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (739 aa) |
| | Phep_0746 | Protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain. (266 aa) |
| | Phep_0858 | PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (272 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa) |
| | Phep_0869 | PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (395 aa) |
| | Phep_0873 | Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (319 aa) |
| | Phep_0874 | PFAM: Transketolase, thiamine diphosphate binding domain. (281 aa) |
| | Phep_0882 | PFAM: Fumarylacetoacetate (FAA) hydrolase family. (203 aa) |
| | Phep_1042 | PFAM: ROK family. (289 aa) |
| | Phep_1134 | Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold. (442 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa) |
| | Phep_1209 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (453 aa) |
| | Phep_1212 | Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (446 aa) |
| | Phep_1346 | PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. (301 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa) |
| | Phep_1415 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | Phep_1518 | HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. (216 aa) |
| | Phep_1564 | methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. (134 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa) |
| | Phep_1609 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme. (349 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (241 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (503 aa) |
| | Phep_1676 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa) |
| | Phep_1677 | PFAM: ROK family. (254 aa) |
| | Phep_1678 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (333 aa) |
| | Phep_1855 | PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa) |
| | Phep_1858 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (316 aa) |
| | Phep_1873 | PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase. (413 aa) |
| | Phep_1875 | PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (434 aa) |
| | Phep_1894 | PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain. (299 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (217 aa) |
| | Phep_2053 | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (428 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | Phep_2100 | PFAM: Aldehyde dehydrogenase family. (457 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (219 aa) |
| | Phep_2131 | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. (1502 aa) |
| | Phep_2132 | Glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit. (488 aa) |
| | Phep_2135 | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (345 aa) |
| | Phep_2264 | PfkB domain protein; PFAM: pfkB family carbohydrate kinase. (331 aa) |
| | Phep_2265 | PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase. (217 aa) |
| | Phep_2271 | PFAM: Aldehyde dehydrogenase family. (541 aa) |
| | fabV | Trans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa) |
| | Phep_2313 | Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (252 aa) |
| | Phep_2329 | PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain. (396 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (384 aa) |
| | Phep_2333 | PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. (437 aa) |
| | Phep_2334 | Glucose-1,6-bisphosphate synthase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II. (577 aa) |
| | mqo | PFAM: FAD dependent oxidoreductase; TIGRFAM: malate:quinone-oxidoreductase. (497 aa) |
| | Phep_2363 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase. (270 aa) |
| | Phep_2381 | Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain. (621 aa) |
| | Phep_2404 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa) |
| | Phep_2418 | PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (509 aa) |
| | Phep_2450 | Sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. (149 aa) |
| | Phep_2597 | PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain. (388 aa) |
| | Phep_2727 | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (390 aa) |
| | Phep_2730 | Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase. (232 aa) |
| | Phep_2740 | Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (262 aa) |
| | Phep_2747 | PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain; Belongs to the RuBisCO large chain family. (416 aa) |
| | Phep_2799 | PFAM: Transketolase, thiamine diphosphate binding domain. (274 aa) |
| | Phep_2800 | Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (320 aa) |
| | Phep_2814 | PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family. (311 aa) |
| | Phep_2823 | PFAM: ROK family. (283 aa) |
| | Phep_2901 | acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa) |
| | Phep_2925 | PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. (424 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (188 aa) |
| | Phep_2950 | Carboxymethylenebutenolidase; PFAM: Dienelactone hydrolase family. (295 aa) |
| | fbp | Inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase. (361 aa) |
| | Phep_2977 | PFAM: Glutamine synthetase, catalytic domain. (728 aa) |
| | Phep_3001 | Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: dihydrolipoamide dehydrogenase. (462 aa) |
| | Phep_3005 | PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (482 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa) |
| | Phep_3045 | PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (377 aa) |
| | Phep_3087 | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (416 aa) |
| | Phep_3088 | Sulfate adenylyltransferase, small subunit; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, small subunit. (301 aa) |
| | Phep_3089 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (234 aa) |
| | Phep_3091 | uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (263 aa) |
| | Phep_3092 | PFAM: HEPN domain; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain. (697 aa) |
| | Phep_3219 | PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (473 aa) |
| | Phep_3263 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (248 aa) |
| | Phep_3264 | PFAM: Glucose inhibited division protein A; Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. (638 aa) |
| | Phep_3265 | TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (224 aa) |
| | Phep_3277 | PFAM: Fumarylacetoacetate (FAA) hydrolase family. (332 aa) |
| | Phep_3280 | PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase. (385 aa) |
| | Phep_3289 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (496 aa) |
| | Phep_3290 | Threonine aldolase; PFAM: Beta-eliminating lyase. (344 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa) |
| | Phep_3295 | PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa) |
| | pgk | PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | Phep_3337 | PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | Phep_3355 | PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain. (347 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (457 aa) |
| | Phep_3449 | Porphobilinogen synthase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (322 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (526 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (409 aa) |
| | Phep_3478 | PFAM: Fructose-bisphosphate aldolase class-I. (348 aa) |
| | Phep_3505 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (319 aa) |
| | Phep_3517 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (632 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa) |
| | Phep_3565 | PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa) |
| | Phep_3570 | SMP-30/Gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region. (268 aa) |
| | Phep_3574 | Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (379 aa) |
| | Phep_3581 | PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family. (286 aa) |
| | Phep_3585 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (812 aa) |
| | Phep_3607 | methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain. (515 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa) |
| | Phep_3710 | Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: dihydrolipoamide dehydrogenase. (467 aa) |
| | Phep_3715 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (412 aa) |
| | Phep_3716 | 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. (931 aa) |
| | Phep_3723 | acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | Phep_3724 | PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (787 aa) |
| | Phep_3800 | PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (318 aa) |
| | Phep_3802 | Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (439 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (311 aa) |
| | Phep_3804 | Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class. (815 aa) |
| | Phep_3811 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (307 aa) |
| | Phep_3818 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | Phep_3819 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa) |
| | Phep_3821 | PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B. (146 aa) |
| | Phep_3833 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. (771 aa) |
| | Phep_3843 | PFAM: Acylphosphatase. (92 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa) |
| | Phep_3882 | PFAM: FGGY family of carbohydrate kinases, N-terminal domain. (467 aa) |
| | Phep_3883 | PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype. (424 aa) |
| | Phep_4015 | Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (259 aa) |
| | Phep_4016 | PFAM: Amidohydrolase. (276 aa) |
| | Phep_4018 | Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (254 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (533 aa) |
| | Phep_4158 | PFAM: (2R)-phospho-3-sulfolactate synthase (ComA). (255 aa) |
| | Phep_4178 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa) |
| | Phep_4190 | PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa) |
| | Phep_4207 | PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (377 aa) |
| | Phep_4240 | Cobalamin B12-binding domain protein; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain. (139 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (502 aa) |
| | Phep_4263 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (862 aa) |
| | Phep_4268 | PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (462 aa) |
