40 items (Penicillium freii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACN42_g4861	Uncharacterized protein. (1021 aa)
	ACN42_g6916	Uncharacterized protein. (78 aa)
	ACN42_g11677	Uncharacterized protein. (147 aa)
	ACN42_g11153	Uncharacterized protein; Belongs to the cyclin family. (364 aa)
	ACN42_g10447	Uncharacterized protein. (729 aa)
	ACN42_g8830	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (480 aa)
	ACN42_g8719	Uncharacterized protein. (74 aa)
	ACN42_g8618	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	ACN42_g8264	RPOL9 domain-containing protein. (136 aa)
	ACN42_g8210	Uncharacterized protein. (72 aa)
	ACN42_g7188	Uncharacterized protein. (364 aa)
	ACN42_g6600	CYCLIN domain-containing protein; Belongs to the cyclin family. (428 aa)
	ACN42_g6480	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (618 aa)
	ACN42_g5507	BSD domain-containing protein. (643 aa)
	ACN42_g5296	Helicase ATP-binding domain-containing protein. (795 aa)
	ACN42_g4675	Uncharacterized protein. (153 aa)
	ACN42_g3763	Uncharacterized protein; Belongs to the cyclin family. (334 aa)
	ACN42_g2679	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (815 aa)
	ACN42_g1887	Uncharacterized protein. (298 aa)
	ACN42_g1666	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1737 aa)
	ACN42_g1373	RING-type domain-containing protein. (370 aa)
	ACN42_g1408	RPOL4c domain-containing protein. (148 aa)
	ACN42_g1073	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (690 aa)
	ACN42_g10307	RPOLD domain-containing protein. (335 aa)
	ACN42_g9706	RNA_pol_L_2 domain-containing protein. (163 aa)
	ACN42_g9642	TPR_REGION domain-containing protein. (395 aa)
	ACN42_g9495	Uncharacterized protein. (306 aa)
	ACN42_g8124	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (120 aa)
	ACN42_g4719	Uncharacterized protein. (379 aa)
	ACN42_g4305	Protein kinase domain-containing protein. (521 aa)
	ACN42_g3924	Uncharacterized protein; Belongs to the SKP1 family. (101 aa)
	ACN42_g3507	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	ACN42_g2016	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1025 aa)
	ACN42_g1190	Uncharacterized protein. (819 aa)
	ACN42_g647	Uncharacterized protein. (822 aa)
	ACN42_g10186	Protein kinase domain-containing protein. (1086 aa)
	ACN42_g153	Uncharacterized protein. (169 aa)
	ACN42_g154	Uncharacterized protein. (567 aa)
	ACN42_g1800	Uncharacterized protein. (234 aa)
	ACN42_g4626	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1325 aa)

Your Current Organism:

Penicillium freii

NCBI taxonomy Id: 48697
Other names: CBS 476.84, IMI 285515, P. freii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACN42_g10186	ACN42_g10307	A0A124GQ49	A0A117NKZ2	Protein kinase domain-containing protein.	RPOLD domain-containing protein.	0.764
ACN42_g10186	ACN42_g10447	A0A124GQ49	A0A101MAB4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.905
ACN42_g10186	ACN42_g11153	A0A124GQ49	A0A101M8N4	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the cyclin family.	0.945
ACN42_g10186	ACN42_g11677	A0A124GQ49	A0A101M7Z0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.945
ACN42_g10186	ACN42_g1190	A0A124GQ49	A0A117NRS5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.658
ACN42_g10186	ACN42_g1373	A0A124GQ49	A0A101MS11	Protein kinase domain-containing protein.	RING-type domain-containing protein.	0.663
ACN42_g10186	ACN42_g1408	A0A124GQ49	A0A101MS29	Protein kinase domain-containing protein.	RPOL4c domain-containing protein.	0.690
ACN42_g10186	ACN42_g153	A0A124GQ49	A0A124GTM9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.657
ACN42_g10186	ACN42_g154	A0A124GQ49	A0A124GTM4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.642
ACN42_g10186	ACN42_g1666	A0A124GQ49	A0A101MRM0	Protein kinase domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.972
ACN42_g10186	ACN42_g1800	A0A124GQ49	A0A124GSR5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.651
ACN42_g10186	ACN42_g1887	A0A124GQ49	A0A101MR36	Protein kinase domain-containing protein.	Uncharacterized protein.	0.678
ACN42_g10186	ACN42_g2016	A0A124GQ49	A0A117NR96	Protein kinase domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.949
ACN42_g10186	ACN42_g2679	A0A124GQ49	A0A101MPP6	Protein kinase domain-containing protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.823
ACN42_g10186	ACN42_g3507	A0A124GQ49	A0A117NQA1	Protein kinase domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.647
ACN42_g10186	ACN42_g3763	A0A124GQ49	A0A101MMQ7	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the cyclin family.	0.988
ACN42_g10186	ACN42_g4305	A0A124GQ49	A0A117NPQ3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.784
ACN42_g10186	ACN42_g4626	A0A124GQ49	A0A124GRW0	Protein kinase domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.694
ACN42_g10186	ACN42_g4675	A0A124GQ49	A0A101MKU3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.662
ACN42_g10186	ACN42_g4861	A0A124GQ49	A0A124GRT2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.758