30 items (Penicillium freii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	ACN42_g4876	Uncharacterized protein. (622 aa)
	ACN42_g4949	3'-5' exonuclease domain-containing protein. (1265 aa)
	ACN42_g5854	ATP-dependent DNA helicase; Belongs to the helicase family. (129 aa)
	ACN42_g7707	Uncharacterized protein. (1096 aa)
	ACN42_g8724	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	ACN42_g9296	Uncharacterized protein. (258 aa)
	ACN42_g10080	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1225 aa)
	ACN42_g10534	AAA domain-containing protein. (1050 aa)
	ACN42_g10957	Uncharacterized protein. (596 aa)
	ACN42_g10958	AAA_12 domain-containing protein. (156 aa)
	ACN42_g118	Uncharacterized protein. (283 aa)
	ACN42_g80	Uncharacterized protein. (425 aa)
	ACN42_g1467	Ribosomal_L7Ae domain-containing protein. (222 aa)
	ACN42_g3420	TruB_N domain-containing protein. (394 aa)
	ACN42_g4544	Uncharacterized protein. (153 aa)
	ACN42_g4545	Uncharacterized protein. (197 aa)
	ACN42_g6981	Uncharacterized protein. (395 aa)
	ACN42_g7486	Uncharacterized protein. (122 aa)
	ACN42_g4278	PUA domain-containing protein. (473 aa)
	ACN42_g10901	Uncharacterized protein. (1410 aa)
	ACN42_g10959	Uncharacterized protein. (92 aa)
	ACN42_g1564	Uncharacterized protein. (124 aa)
	ACN42_g1703	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (510 aa)
	ACN42_g2251	Uncharacterized protein. (1500 aa)
	ACN42_g3206	Histone H2B; Belongs to the histone H2B family. (141 aa)
	ACN42_g3930	Uncharacterized protein. (184 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (718 aa)
	ACN42_g4368	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (469 aa)
	ACN42_g4552	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	ACN42_g4837	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (213 aa)

Your Current Organism:

Penicillium freii

NCBI taxonomy Id: 48697
Other names: CBS 476.84, IMI 285515, P. freii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACN42_g10080	ACN42_g10901	A0A101MAY5	A0A117NKL8	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.432
ACN42_g10080	ACN42_g10957	A0A101MAY5	A0A101M940	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.642
ACN42_g10080	ACN42_g10958	A0A101MAY5	A0A101M904	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	AAA_12 domain-containing protein.	0.694
ACN42_g10080	ACN42_g10959	A0A101MAY5	A0A117NKK6	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.694
ACN42_g10080	ACN42_g118	A0A101MAY5	A0A124GTS3	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.980
ACN42_g10080	ACN42_g1467	A0A101MAY5	A0A124GSV6	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Ribosomal_L7Ae domain-containing protein.	0.855
ACN42_g10080	ACN42_g1564	A0A101MAY5	A0A101MRR0	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.838
ACN42_g10080	ACN42_g1703	A0A101MAY5	A0A101MRI1	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.547
ACN42_g10080	ACN42_g2251	A0A101MAY5	A0A101MQJ5	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.547
ACN42_g10080	ACN42_g3420	A0A101MAY5	A0A124GS89	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	TruB_N domain-containing protein.	0.884
ACN42_g10080	ACN42_g4278	A0A101MAY5	A0A117NPT8	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	PUA domain-containing protein.	0.913
ACN42_g10080	ACN42_g4368	A0A101MAY5	A0A101MLF8	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.699
ACN42_g10080	ACN42_g4552	A0A101MAY5	A0A101ML35	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.712
ACN42_g10080	ACN42_g4837	A0A101MAY5	A0A101MKJ1	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.840
ACN42_g10080	ACN42_g4949	A0A101MAY5	A0A101MKC2	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	3'-5' exonuclease domain-containing protein.	0.677
ACN42_g10080	ACN42_g5854	A0A101MAY5	A0A101MIK9	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	ATP-dependent DNA helicase; Belongs to the helicase family.	0.642
ACN42_g10080	ACN42_g6981	A0A101MAY5	A0A124GR53	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.869
ACN42_g10080	ACN42_g7486	A0A101MAY5	A0A124GQZ0	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.642
ACN42_g10080	ACN42_g8724	A0A101MAY5	A0A101MD99	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.930
ACN42_g10080	ACN42_g9296	A0A101MAY5	A0A101MC71	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	Uncharacterized protein.	0.642