41 items (Penicillium freii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACN42_g1373	RING-type domain-containing protein. (370 aa)
	ACN42_g11348	CDC73_C domain-containing protein. (502 aa)
	ACN42_g10462	Uncharacterized protein. (822 aa)
	ACN42_g10447	Uncharacterized protein. (729 aa)
	ACN42_g8830	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (480 aa)
	ACN42_g8719	Uncharacterized protein. (74 aa)
	ACN42_g8618	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	ACN42_g8456	Uncharacterized protein. (485 aa)
	ACN42_g8269	Nuclear cap-binding protein subunit 2. (72 aa)
	ACN42_g8264	RPOL9 domain-containing protein. (136 aa)
	ACN42_g8270	Nuclear cap-binding protein subunit 2. (98 aa)
	ACN42_g8210	Uncharacterized protein. (72 aa)
	ACN42_g7835	Uncharacterized protein. (1198 aa)
	ACN42_g7188	Uncharacterized protein. (364 aa)
	ACN42_g6792	Uncharacterized protein. (589 aa)
	ACN42_g6600	CYCLIN domain-containing protein; Belongs to the cyclin family. (428 aa)
	ACN42_g5808	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1411 aa)
	ACN42_g5507	BSD domain-containing protein. (643 aa)
	ACN42_g5296	Helicase ATP-binding domain-containing protein. (795 aa)
	ACN42_g4675	Uncharacterized protein. (153 aa)
	ACN42_g2679	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (815 aa)
	ACN42_g1666	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1737 aa)
	ACN42_g1408	RPOL4c domain-containing protein. (148 aa)
	ACN42_g1073	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (690 aa)
	ACN42_g948	Uncharacterized protein. (435 aa)
	ACN42_g10307	RPOLD domain-containing protein. (335 aa)
	ACN42_g9706	RNA_pol_L_2 domain-containing protein. (163 aa)
	ACN42_g9642	TPR_REGION domain-containing protein. (395 aa)
	ACN42_g8124	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (120 aa)
	ACN42_g4719	Uncharacterized protein. (379 aa)
	ACN42_g4112	Uncharacterized protein. (672 aa)
	ACN42_g3507	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
	ACN42_g2016	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1025 aa)
	ACN42_g647	Uncharacterized protein. (822 aa)
	ACN42_g8294	TFIIS N-terminal domain-containing protein. (443 aa)
	ACN42_g6916	Uncharacterized protein. (78 aa)
	ACN42_g4626	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1325 aa)
	ACN42_g1800	Uncharacterized protein. (234 aa)
	ACN42_g493	Plus3 domain-containing protein. (611 aa)
	ACN42_g154	Uncharacterized protein. (567 aa)
	ACN42_g153	Uncharacterized protein. (169 aa)

Your Current Organism:

Penicillium freii

NCBI taxonomy Id: 48697
Other names: CBS 476.84, IMI 285515, P. freii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACN42_g10307	ACN42_g10447	A0A117NKZ2	A0A101MAB4	RPOLD domain-containing protein.	Uncharacterized protein.	0.689
ACN42_g10307	ACN42_g10462	A0A117NKZ2	A0A101M9Z8	RPOLD domain-containing protein.	Uncharacterized protein.	0.737
ACN42_g10307	ACN42_g1073	A0A117NKZ2	A0A101MSL7	RPOLD domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.992
ACN42_g10307	ACN42_g11348	A0A117NKZ2	A0A101M8E6	RPOLD domain-containing protein.	CDC73_C domain-containing protein.	0.952
ACN42_g10307	ACN42_g1373	A0A117NKZ2	A0A101MS11	RPOLD domain-containing protein.	RING-type domain-containing protein.	0.988
ACN42_g10307	ACN42_g1408	A0A117NKZ2	A0A101MS29	RPOLD domain-containing protein.	RPOL4c domain-containing protein.	0.999
ACN42_g10307	ACN42_g153	A0A117NKZ2	A0A124GTM9	RPOLD domain-containing protein.	Uncharacterized protein.	0.999
ACN42_g10307	ACN42_g154	A0A117NKZ2	A0A124GTM4	RPOLD domain-containing protein.	Uncharacterized protein.	0.980
ACN42_g10307	ACN42_g1666	A0A117NKZ2	A0A101MRM0	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
ACN42_g10307	ACN42_g1800	A0A117NKZ2	A0A124GSR5	RPOLD domain-containing protein.	Uncharacterized protein.	0.999
ACN42_g10307	ACN42_g2016	A0A117NKZ2	A0A117NR96	RPOLD domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.995
ACN42_g10307	ACN42_g2679	A0A117NKZ2	A0A101MPP6	RPOLD domain-containing protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.986
ACN42_g10307	ACN42_g3507	A0A117NKZ2	A0A117NQA1	RPOLD domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
ACN42_g10307	ACN42_g4112	A0A117NKZ2	A0A117NPU5	RPOLD domain-containing protein.	Uncharacterized protein.	0.766
ACN42_g10307	ACN42_g4626	A0A117NKZ2	A0A124GRW0	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
ACN42_g10307	ACN42_g4675	A0A117NKZ2	A0A101MKU3	RPOLD domain-containing protein.	Uncharacterized protein.	0.999
ACN42_g10307	ACN42_g4719	A0A117NKZ2	A0A117NPJ2	RPOLD domain-containing protein.	Uncharacterized protein.	0.980
ACN42_g10307	ACN42_g493	A0A117NKZ2	A0A124GTA6	RPOLD domain-containing protein.	Plus3 domain-containing protein.	0.949
ACN42_g10307	ACN42_g5296	A0A117NKZ2	A0A101MJQ7	RPOLD domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.983
ACN42_g10307	ACN42_g5507	A0A117NKZ2	A0A101MJD0	RPOLD domain-containing protein.	BSD domain-containing protein.	0.978