(81 nodes) Mixed, incl. DnaJ domain, conserved site, and Heat shock protein 70 family network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103156730-2	Heat shock 10 protein 1; Belongs to the GroES chaperonin family. (99 aa)
	hspd1	Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family. (575 aa)
	dnajb4	DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
	hspa12a	Heat shock protein 12A. (674 aa)
	hspa9	Heat shock protein 9; Belongs to the heat shock protein 70 family. (679 aa)
	LOC103131486	Uncharacterized protein. (413 aa)
	dnajb11	DnaJ heat shock protein family (Hsp40) member B11. (360 aa)
	ENSPFOP00000000869	Heat shock protein 12B. (694 aa)
	hspa14	Heat shock protein 14; Belongs to the heat shock protein 70 family. (510 aa)
	ENSPFOP00000001392	Uncharacterized protein. (598 aa)
	ENSPFOP00000001472	Uncharacterized protein. (560 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (985 aa)
	dnajc5g	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a. (221 aa)
	dnajc2	DnaJ (Hsp40) homolog, subfamily C, member 2. (617 aa)
	ENSPFOP00000002315	Transmembrane protein 59-like. (343 aa)
	dnajb2	J domain-containing protein. (305 aa)
	LOC103134423	DnaJ heat shock protein family (Hsp40) member B9a. (213 aa)
	HSF1	Heat shock transcription factor 1. (538 aa)
	hsp90b1	Heat shock protein 90, beta (grp94), member 1. (797 aa)
	dnajb1	DnaJ heat shock protein family (Hsp40) member B1b. (354 aa)
	ENSPFOP00000003895	ANK_REP_REGION domain-containing protein. (136 aa)
	DNAJA4	Uncharacterized protein. (395 aa)
	ENSPFOP00000004664	Heat shock transcription factor 4. (444 aa)
	LOC103154827	Uncharacterized protein. (486 aa)
	LOC103142293	DnaJ heat shock protein family (Hsp40) member B12b. (367 aa)
	LOC103137846	DnaJ heat shock protein family (Hsp40) member A1. (407 aa)
	ENSPFOP00000004998	Uncharacterized protein. (412 aa)
	LOC103139084	DnaJ (Hsp40) homolog, subfamily C, member 5aa. (199 aa)
	hspa13	Heat shock protein 70 family, member 13. (442 aa)
	dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3a. (502 aa)
	LOC103144868	Heat shock protein 4a. (836 aa)
	ENSPFOP00000007059	Heat shock cognate 70; Belongs to the heat shock protein 70 family. (649 aa)
	LOC103139657	Uncharacterized protein; Belongs to the heat shock protein 70 family. (637 aa)
	CLPB	ClpB homolog, mitochondrial AAA ATPase chaperonin. (678 aa)
	HSPA8	Heat shock protein 8; Belongs to the heat shock protein 70 family. (646 aa)
	bag3	BCL2 associated athanogene 3. (515 aa)
	ENSPFOP00000009978	SIL1 nucleotide exchange factor. (439 aa)
	dnajc5b	J domain-containing protein. (197 aa)
	dnajc10	DnaJ (Hsp40) homolog, subfamily C, member 10. (792 aa)
	grpel1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (214 aa)
	LOC103135588	Heat shock protein 4b. (845 aa)
	dnaja3	DnaJ heat shock protein family (Hsp40) member A3a. (483 aa)
	tmem59	Transmembrane protein 59. (325 aa)
	ENSPFOP00000011392	DnaJ (Hsp40) homolog, subfamily C, member 1. (503 aa)
	dnajb14	DnaJ heat shock protein family (Hsp40) member B14. (375 aa)
	dnajc7	DnaJ (Hsp40) homolog, subfamily C, member 7. (493 aa)
	DNAJC5	DnaJ (Hsp40) homolog, subfamily C, member 5ab. (158 aa)
	ENSPFOP00000012134	Citrate lyase beta like. (343 aa)
	LOC103137566	DnaJ (Hsp40) homolog, subfamily C, member 3b. (500 aa)
	ENSPFOP00000013135	Uncharacterized protein. (569 aa)
	LOC103133487	DnaJ heat shock protein family (Hsp40) member B12a. (369 aa)
	LOC103155150	Zgc:122979. (383 aa)
	LOC103130041	Thioredoxin domain-containing protein. (517 aa)
	LOC103156682	DnaJ heat shock protein family (Hsp40) member B9b. (226 aa)
	LOC103131003	Uncharacterized protein. (496 aa)
	cdc42se2	CDC42 small effector 2. (76 aa)
	LOC103155532	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
	LOC103152076	Uncharacterized protein. (596 aa)
	LOC103144709	J domain-containing protein. (208 aa)
	dnajb6	DnaJ heat shock protein family (Hsp40) member B6b. (318 aa)
	LOC103132882	Calmegin. (650 aa)
	dnajb5	J domain-containing protein. (369 aa)
	LOC103133785	DnaJ heat shock protein family (Hsp40) member A2b. (412 aa)
	stip1	Stress-induced phosphoprotein 1. (574 aa)
	LOC103141338	DnaJ (Hsp40) homolog, subfamily C, member 18. (389 aa)
	dnajb13	DnaJ heat shock protein family (Hsp40) member B13. (340 aa)
	clpp	ATP-dependent Clp protease proteolytic subunit. (269 aa)
	clpx	Caseinolytic mitochondrial matrix peptidase chaperone subunit b. (624 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
	LOC103132027	Heat shock cognate 70-kd protein, tandem duplicate 3; Belongs to the heat shock protein 70 family. (639 aa)
	ENSPFOP00000021214	Hypoxia up-regulated 1. (982 aa)
	ENSPFOP00000022378	DUF4585 domain-containing protein. (1339 aa)
	ENSPFOP00000022388	Uncharacterized protein. (563 aa)
	pdia6	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family. (440 aa)
	ENSPFOP00000022783	Uncharacterized protein. (480 aa)
	ENSPFOP00000022951	Uncharacterized protein. (242 aa)
	ENSPFOP00000028154	HSF_DOMAIN domain-containing protein. (421 aa)
	ENSPFOP00000028982	Uncharacterized protein. (463 aa)
	LOC103147628	J domain-containing protein. (193 aa)
	LOC103132397	Ig-like domain-containing protein. (580 aa)
	ENSPFOP00000030771	Uncharacterized protein. (239 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPB	DNAJA4	ENSPFOP00000009183	ENSPFOP00000004514	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.750
CLPB	DNAJC5	ENSPFOP00000009183	ENSPFOP00000011955	ClpB homolog, mitochondrial AAA ATPase chaperonin.	DnaJ (Hsp40) homolog, subfamily C, member 5ab.	0.682
CLPB	ENSPFOP00000000869	ENSPFOP00000009183	ENSPFOP00000000869	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock protein 12B.	0.808
CLPB	ENSPFOP00000001392	ENSPFOP00000009183	ENSPFOP00000001392	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000001472	ENSPFOP00000009183	ENSPFOP00000001472	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000002315	ENSPFOP00000009183	ENSPFOP00000002315	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Transmembrane protein 59-like.	0.837
CLPB	ENSPFOP00000003895	ENSPFOP00000009183	ENSPFOP00000003895	ClpB homolog, mitochondrial AAA ATPase chaperonin.	ANK_REP_REGION domain-containing protein.	0.829
CLPB	ENSPFOP00000004664	ENSPFOP00000009183	ENSPFOP00000004664	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock transcription factor 4.	0.520
CLPB	ENSPFOP00000004998	ENSPFOP00000009183	ENSPFOP00000004998	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.750
CLPB	ENSPFOP00000007059	ENSPFOP00000009183	ENSPFOP00000007059	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Heat shock cognate 70; Belongs to the heat shock protein 70 family.	0.837
CLPB	ENSPFOP00000009978	ENSPFOP00000009183	ENSPFOP00000009978	ClpB homolog, mitochondrial AAA ATPase chaperonin.	SIL1 nucleotide exchange factor.	0.574
CLPB	ENSPFOP00000012134	ENSPFOP00000009183	ENSPFOP00000012134	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Citrate lyase beta like.	0.686
CLPB	ENSPFOP00000013135	ENSPFOP00000009183	ENSPFOP00000013135	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000021214	ENSPFOP00000009183	ENSPFOP00000021214	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Hypoxia up-regulated 1.	0.832
CLPB	ENSPFOP00000022378	ENSPFOP00000009183	ENSPFOP00000022378	ClpB homolog, mitochondrial AAA ATPase chaperonin.	DUF4585 domain-containing protein.	0.808
CLPB	ENSPFOP00000022388	ENSPFOP00000009183	ENSPFOP00000022388	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000022783	ENSPFOP00000009183	ENSPFOP00000022783	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000022951	ENSPFOP00000009183	ENSPFOP00000022951	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000028982	ENSPFOP00000009183	ENSPFOP00000028982	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808
CLPB	ENSPFOP00000030771	ENSPFOP00000009183	ENSPFOP00000030771	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Uncharacterized protein.	0.808