(23 nodes) Mixed, incl. Activation of C3 and C5, and Peptidase S1A, complement C1r/C1S/mannan-binding network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000000179	C-type lectin domain-containing protein. (240 aa)
	cfi	Uncharacterized protein; Belongs to the peptidase S1 family. (645 aa)
	ENSPFOP00000003169	Uncharacterized protein. (321 aa)
	ENSPFOP00000003633	Uncharacterized protein. (1112 aa)
	LOC103153241	Complement component c3b, tandem duplicate 2. (1754 aa)
	ENSPFOP00000006220	Uncharacterized protein. (1662 aa)
	ENSPFOP00000007593	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family. (599 aa)
	COLEC10	Collectin subfamily member 10. (283 aa)
	LOC103154630	Si:ch1073-280e3.1; Belongs to the peptidase S1 family. (768 aa)
	masp1	Mannan-binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (708 aa)
	ENSPFOP00000010003	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (254 aa)
	cfp	Uncharacterized protein. (566 aa)
	LOC103150407	Complement 4B (Chido blood group). (1708 aa)
	LOC103154447	C1q domain-containing protein. (257 aa)
	ENSPFOP00000013824	C-type lectin domain-containing protein. (319 aa)
	ENSPFOP00000013864	Complement component 1, r subcomponent; Belongs to the peptidase S1 family. (705 aa)
	LOC103143314	Uncharacterized protein. (376 aa)
	LOC103141081	Uncharacterized protein; Belongs to the peptidase S1 family. (763 aa)
	C5AR2	Complement component 5a receptor 2. (350 aa)
	LOC103133105	Uncharacterized protein. (1035 aa)
	ENSPFOP00000025082	Uncharacterized protein; Belongs to the peptidase S1 family. (653 aa)
	ENSPFOP00000027895	Uncharacterized protein. (1004 aa)
	ENSPFOP00000030007	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (330 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5AR2	ENSPFOP00000003633	ENSPFOP00000020998	ENSPFOP00000003633	Complement component 5a receptor 2.	Uncharacterized protein.	0.625
C5AR2	ENSPFOP00000006220	ENSPFOP00000020998	ENSPFOP00000006220	Complement component 5a receptor 2.	Uncharacterized protein.	0.625
C5AR2	ENSPFOP00000027895	ENSPFOP00000020998	ENSPFOP00000027895	Complement component 5a receptor 2.	Uncharacterized protein.	0.625
C5AR2	LOC103133105	ENSPFOP00000020998	ENSPFOP00000024983	Complement component 5a receptor 2.	Uncharacterized protein.	0.625
C5AR2	LOC103150407	ENSPFOP00000020998	ENSPFOP00000010657	Complement component 5a receptor 2.	Complement 4B (Chido blood group).	0.625
C5AR2	LOC103153241	ENSPFOP00000020998	ENSPFOP00000006129	Complement component 5a receptor 2.	Complement component c3b, tandem duplicate 2.	0.625
COLEC10	ENSPFOP00000000179	ENSPFOP00000008395	ENSPFOP00000000179	Collectin subfamily member 10.	C-type lectin domain-containing protein.	0.600
COLEC10	ENSPFOP00000003633	ENSPFOP00000008395	ENSPFOP00000003633	Collectin subfamily member 10.	Uncharacterized protein.	0.408
COLEC10	ENSPFOP00000006220	ENSPFOP00000008395	ENSPFOP00000006220	Collectin subfamily member 10.	Uncharacterized protein.	0.408
COLEC10	ENSPFOP00000007593	ENSPFOP00000008395	ENSPFOP00000007593	Collectin subfamily member 10.	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.	0.486
COLEC10	ENSPFOP00000013824	ENSPFOP00000008395	ENSPFOP00000013824	Collectin subfamily member 10.	C-type lectin domain-containing protein.	0.632
COLEC10	ENSPFOP00000013864	ENSPFOP00000008395	ENSPFOP00000013864	Collectin subfamily member 10.	Complement component 1, r subcomponent; Belongs to the peptidase S1 family.	0.729
COLEC10	ENSPFOP00000025082	ENSPFOP00000008395	ENSPFOP00000025082	Collectin subfamily member 10.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.729
COLEC10	ENSPFOP00000027895	ENSPFOP00000008395	ENSPFOP00000027895	Collectin subfamily member 10.	Uncharacterized protein.	0.412
COLEC10	LOC103133105	ENSPFOP00000008395	ENSPFOP00000024983	Collectin subfamily member 10.	Uncharacterized protein.	0.412
COLEC10	LOC103141081	ENSPFOP00000008395	ENSPFOP00000018769	Collectin subfamily member 10.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.454
COLEC10	LOC103150407	ENSPFOP00000008395	ENSPFOP00000010657	Collectin subfamily member 10.	Complement 4B (Chido blood group).	0.408
COLEC10	LOC103153241	ENSPFOP00000008395	ENSPFOP00000006129	Collectin subfamily member 10.	Complement component c3b, tandem duplicate 2.	0.408
COLEC10	LOC103154447	ENSPFOP00000008395	ENSPFOP00000011139	Collectin subfamily member 10.	C1q domain-containing protein.	0.509
COLEC10	LOC103154630	ENSPFOP00000008395	ENSPFOP00000008411	Collectin subfamily member 10.	Si:ch1073-280e3.1; Belongs to the peptidase S1 family.	0.448