32 items (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	FBXO40	F-box protein 40. (690 aa)
	fnta	Farnesyltransferase, CAAX box, alpha. (368 aa)
	LOC103132185	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	dhdds	Alkyl transferase; Belongs to the UPP synthase family. (335 aa)
	COQ2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (374 aa)
	ENSPFOP00000008457	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (448 aa)
	pmvk	Phosphomevalonate kinase. (264 aa)
	LOC103135855	3-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
	rusc2	RUN and SH3 domain containing 2. (1575 aa)
	ENSPFOP00000011785	Ras converting CAAX endopeptidase 1a. (300 aa)
	ENSPFOP00000012488	Pyridine nucleotide-disulphide oxidoreductase domain 2. (576 aa)
	idi1	Isopentenyl-diphosphate delta isomerase 1. (286 aa)
	pdss2	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (385 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	fdps	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)
	nus1	NUS1 dehydrodolichyl diphosphate synthase subunit. (288 aa)
	LOC103144688	F-box protein 30a. (710 aa)
	insig1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (275 aa)
	ubiad1	UbiA prenyltransferase domain containing 1. (354 aa)
	icmt	Protein-S-isoprenylcysteine O-methyltransferase. (291 aa)
	LOC103130771	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (432 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (404 aa)
	churc1	Churchill domain containing 1. (112 aa)
	ggps1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (315 aa)
	LOC103134931	Uncharacterized protein. (739 aa)
	ENSPFOP00000021252	3-hydroxy-3-methylglutaryl coenzyme A reductase. (815 aa)
	ENSPFOP00000021874	Protein geranylgeranyltransferase type I, beta subunit. (374 aa)
	ENSPFOP00000025013	Uncharacterized protein. (1837 aa)
	ENSPFOP00000025370	Uncharacterized protein. (654 aa)
	ENSPFOP00000025881	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (380 aa)
	ENSPFOP00000027029	Pyridine nucleotide-disulphide oxidoreductase domain 2. (465 aa)
	LOC103148254	RUN domain-containing protein. (1167 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ2	ENSPFOP00000008457	ENSPFOP00000007904	ENSPFOP00000008457	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	0.963
COQ2	ENSPFOP00000012488	ENSPFOP00000007904	ENSPFOP00000012488	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Pyridine nucleotide-disulphide oxidoreductase domain 2.	0.768
COQ2	ENSPFOP00000021252	ENSPFOP00000007904	ENSPFOP00000021252	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.502
COQ2	ENSPFOP00000025013	ENSPFOP00000007904	ENSPFOP00000025013	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Uncharacterized protein.	0.783
COQ2	ENSPFOP00000025370	ENSPFOP00000007904	ENSPFOP00000025370	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Uncharacterized protein.	0.807
COQ2	ENSPFOP00000025881	ENSPFOP00000007904	ENSPFOP00000025881	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.639
COQ2	ENSPFOP00000027029	ENSPFOP00000007904	ENSPFOP00000027029	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Pyridine nucleotide-disulphide oxidoreductase domain 2.	0.768
COQ2	FBXO40	ENSPFOP00000007904	ENSPFOP00000000644	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	F-box protein 40.	0.786
COQ2	LOC103132185	ENSPFOP00000007904	ENSPFOP00000005251	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.502
COQ2	LOC103134931	ENSPFOP00000007904	ENSPFOP00000019727	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Uncharacterized protein.	0.786
COQ2	LOC103135855	ENSPFOP00000007904	ENSPFOP00000009402	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.502
COQ2	LOC103144688	ENSPFOP00000007904	ENSPFOP00000015003	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	F-box protein 30a.	0.786
COQ2	LOC103148254	ENSPFOP00000007904	ENSPFOP00000030904	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	RUN domain-containing protein.	0.783
COQ2	dhdds	ENSPFOP00000007904	ENSPFOP00000006075	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Alkyl transferase; Belongs to the UPP synthase family.	0.907
COQ2	fdps	ENSPFOP00000007904	ENSPFOP00000014399	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.786
COQ2	ggps1	ENSPFOP00000007904	ENSPFOP00000019544	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.866
COQ2	idi1	ENSPFOP00000007904	ENSPFOP00000012892	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Isopentenyl-diphosphate delta isomerase 1.	0.940
COQ2	mvd	ENSPFOP00000007904	ENSPFOP00000017909	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.679
COQ2	nus1	ENSPFOP00000007904	ENSPFOP00000014940	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	NUS1 dehydrodolichyl diphosphate synthase subunit.	0.907
COQ2	pdss2	ENSPFOP00000007904	ENSPFOP00000012896	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family.	0.963