(5 nodes) TRAIL signaling network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000001943	TNF superfamily member 10; Belongs to the tumor necrosis factor family. (283 aa)
	LOC103152816	Uncharacterized protein. (377 aa)
	ENSPFOP00000009027	Uncharacterized protein. (205 aa)
	LOC103135859	Tumor necrosis factor receptor superfamily, member a. (446 aa)
	LOC103146539	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (289 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000001943	LOC103135859	ENSPFOP00000001943	ENSPFOP00000009590	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily, member a.	0.906
ENSPFOP00000001943	LOC103146539	ENSPFOP00000001943	ENSPFOP00000012545	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.948
ENSPFOP00000001943	LOC103152816	ENSPFOP00000001943	ENSPFOP00000007115	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.907
ENSPFOP00000009027	LOC103135859	ENSPFOP00000009027	ENSPFOP00000009590	Uncharacterized protein.	Tumor necrosis factor receptor superfamily, member a.	0.837
ENSPFOP00000009027	LOC103152816	ENSPFOP00000009027	ENSPFOP00000007115	Uncharacterized protein.	Uncharacterized protein.	0.889
LOC103135859	ENSPFOP00000001943	ENSPFOP00000009590	ENSPFOP00000001943	Tumor necrosis factor receptor superfamily, member a.	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	0.906
LOC103135859	ENSPFOP00000009027	ENSPFOP00000009590	ENSPFOP00000009027	Tumor necrosis factor receptor superfamily, member a.	Uncharacterized protein.	0.837
LOC103135859	LOC103146539	ENSPFOP00000009590	ENSPFOP00000012545	Tumor necrosis factor receptor superfamily, member a.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.950
LOC103135859	LOC103152816	ENSPFOP00000009590	ENSPFOP00000007115	Tumor necrosis factor receptor superfamily, member a.	Uncharacterized protein.	0.928
LOC103146539	ENSPFOP00000001943	ENSPFOP00000012545	ENSPFOP00000001943	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	0.948
LOC103146539	LOC103135859	ENSPFOP00000012545	ENSPFOP00000009590	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily, member a.	0.950
LOC103146539	LOC103152816	ENSPFOP00000012545	ENSPFOP00000007115	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.954
LOC103152816	ENSPFOP00000001943	ENSPFOP00000007115	ENSPFOP00000001943	Uncharacterized protein.	TNF superfamily member 10; Belongs to the tumor necrosis factor family.	0.907
LOC103152816	ENSPFOP00000009027	ENSPFOP00000007115	ENSPFOP00000009027	Uncharacterized protein.	Uncharacterized protein.	0.889
LOC103152816	LOC103135859	ENSPFOP00000007115	ENSPFOP00000009590	Uncharacterized protein.	Tumor necrosis factor receptor superfamily, member a.	0.928
LOC103152816	LOC103146539	ENSPFOP00000007115	ENSPFOP00000012545	Uncharacterized protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.954