(92 nodes) Mixed, incl. TRIAD supradomain, and TNFs bind their physiological receptors network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000000337	Uncharacterized protein. (275 aa)
	LOC103131859	RBR-type E3 ubiquitin transferase. (279 aa)
	LOC103154654	Tumor necrosis factor b (TNF superfamily, member 2). (249 aa)
	LOC103149726	Uncharacterized protein. (301 aa)
	ENSPFOP00000001741	Tumor necrosis factor receptor superfamily, member 11b. (278 aa)
	rnf31	Ring finger protein 31. (1111 aa)
	LOC103155324	TNFR-Cys domain-containing protein. (260 aa)
	ENSPFOP00000002149	Tax1 (human T-cell leukemia virus type I) binding protein 1a. (757 aa)
	rbck1	RanBP-type and C3HC4-type zinc finger containing 1. (512 aa)
	edaradd	EDAR-associated death domain. (218 aa)
	tnfsf11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	LOC103143442	RBR-type E3 ubiquitin transferase. (714 aa)
	tnip1	TNFAIP3 interacting protein 1. (659 aa)
	LOC103144628	Uncharacterized protein. (964 aa)
	LOC103154153	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (259 aa)
	ENSPFOP00000003085	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
	LOC103135233	Sharpin and rbck1 related. (705 aa)
	ENSPFOP00000004112	RBR-type E3 ubiquitin transferase. (272 aa)
	tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1b. (839 aa)
	ENSPFOP00000004533	TNF superfamily member 14; Belongs to the tumor necrosis factor family. (242 aa)
	edar	Ectodysplasin A receptor. (522 aa)
	ENSPFOP00000004895	NACHT domain-containing protein. (910 aa)
	rnf11	Ring finger protein 11b. (154 aa)
	ndrg4	NDRG family member 4. (352 aa)
	vcpip1	Valosin containing protein (p97)/p47 complex interacting protein 1. (1158 aa)
	LOC103150965	CD40 molecule, TNF receptor superfamily member 5. (313 aa)
	ENSPFOP00000007025	Pleckstrin homology domain containing, family G (with RhoGef domain) member 5b. (1049 aa)
	clip3	CAP-GLY domain containing linker protein 3. (610 aa)
	spata2	Spermatogenesis associated 2. (566 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (658 aa)
	TNFRSF11B	TNF receptor superfamily member 11b. (411 aa)
	ENSPFOP00000008496	TNFR-Cys domain-containing protein. (293 aa)
	ENSPFOP00000008503	TNFR-Cys domain-containing protein. (289 aa)
	nsmaf	Neutral sphingomyelinase (N-SMase) activation associated factor. (911 aa)
	ENSPFOP00000009542	Tripartite motif containing 46b. (800 aa)
	ENSPFOP00000009722	Uncharacterized protein. (247 aa)
	ENSPFOP00000009733	Uncharacterized protein. (273 aa)
	rnf151	Ring finger protein 151. (245 aa)
	ENSPFOP00000010740	WD repeat and FYVE domain containing 3. (1901 aa)
	otud7b	OTU deubiquitinase 7B. (912 aa)
	ENSPFOP00000010953	Uncharacterized protein. (711 aa)
	ENSPFOP00000011259	Si:dkey-181m9.8. (859 aa)
	ENSPFOP00000011966	RBR-type E3 ubiquitin transferase. (305 aa)
	clip4	CAP-Gly domain containing linker protein family member 4. (725 aa)
	ENSPFOP00000012177	DOC domain-containing protein. (862 aa)
	ENSPFOP00000012411	Tumor necrosis factor a (TNF superfamily, member 2); Belongs to the tumor necrosis factor family. (249 aa)
	tnfsf12	TNF superfamily member 12; Belongs to the tumor necrosis factor family. (260 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (824 aa)
	ENSPFOP00000012706	RBR-type E3 ubiquitin transferase. (922 aa)
	eda	Ectodysplasin A; Belongs to the tumor necrosis factor family. (369 aa)
	LOC103135647	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (253 aa)
	ENSPFOP00000013165	Uncharacterized protein. (259 aa)
	ENSPFOP00000013194	RBR-type E3 ubiquitin transferase. (275 aa)
	LOC103137586	Uncharacterized protein. (280 aa)
	LOC103137732	Ring finger protein 11a. (147 aa)
	LOC103140155	CD40 ligand; Belongs to the tumor necrosis factor family. (237 aa)
	ENSPFOP00000013677	DH domain-containing protein. (401 aa)
	ltbr	Uncharacterized protein. (302 aa)
	miip	Migration and invasion inhibitory protein. (395 aa)
	LOC103136547	Tumor necrosis factor receptor superfamily, member 1B. (440 aa)
	LOC103150455	Si:ch211-261n11.8. (216 aa)
	LOC103135786	RING-type domain-containing protein. (160 aa)
	LOC103135177	RBR-type E3 ubiquitin transferase. (839 aa)
	rnf216	Ring finger protein 216. (1016 aa)
	ENSPFOP00000015291	SHANK-associated RH domain interacting protein. (435 aa)
	ENSPFOP00000015749	Cylindromatosis (turban tumor syndrome), b. (517 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (947 aa)
	ENSPFOP00000016073	BCL2 associated athanogene 4. (386 aa)
	ENSPFOP00000016083	Pleckstrin homology domain containing, family G (with RhoGef domain) member 7. (420 aa)
	TNFRSF19	TNF receptor superfamily member 19. (372 aa)
	tgfbr3	Transforming growth factor, beta receptor III. (817 aa)
	ENSPFOP00000017537	Mitogen-activated protein kinase kinase kinase. (948 aa)
	ankib1	RBR-type E3 ubiquitin transferase. (1107 aa)
	ENSPFOP00000019519	Uncharacterized protein. (253 aa)
	ENSPFOP00000021123	Uncharacterized protein. (273 aa)
	ENSPFOP00000021337	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (769 aa)
	ENSPFOP00000021860	Uncharacterized protein. (132 aa)
	ENSPFOP00000023509	Uncharacterized protein. (221 aa)
	ENSPFOP00000024345	Ring finger protein 41, like. (300 aa)
	ENSPFOP00000025069	Uncharacterized protein. (166 aa)
	ENSPFOP00000025721	Death domain-containing protein. (104 aa)
	ENSPFOP00000026837	RBR-type E3 ubiquitin transferase. (245 aa)
	LOC103150967	Pleckstrin homology domain containing, family G (with RhoGef domain) member 5b. (759 aa)
	ENSPFOP00000027647	Uncharacterized protein. (225 aa)
	TNFRSF11B-2	TNF receptor superfamily member 11b. (293 aa)
	ENSPFOP00000029105	annotation not available (132 aa)
	OTULIN	OTU deubiquitinase with linear linkage specificity. (294 aa)
	LOC103139242	BCL3 transcription coactivator. (494 aa)
	ENSPFOP00000029509	Uncharacterized protein; Belongs to the cullin family. (2401 aa)
	ENSPFOP00000029585	TNFR-Cys domain-containing protein. (169 aa)
	btla	Ig-like domain-containing protein. (306 aa)
	LOC103155328	Uncharacterized protein. (192 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000000337	ENSPFOP00000007025	ENSPFOP00000000337	ENSPFOP00000007025	Uncharacterized protein.	Pleckstrin homology domain containing, family G (with RhoGef domain) member 5b.	0.400
ENSPFOP00000000337	ENSPFOP00000011259	ENSPFOP00000000337	ENSPFOP00000011259	Uncharacterized protein.	Si:dkey-181m9.8.	0.623
ENSPFOP00000000337	ENSPFOP00000013677	ENSPFOP00000000337	ENSPFOP00000013677	Uncharacterized protein.	DH domain-containing protein.	0.400
ENSPFOP00000000337	ENSPFOP00000016083	ENSPFOP00000000337	ENSPFOP00000016083	Uncharacterized protein.	Pleckstrin homology domain containing, family G (with RhoGef domain) member 7.	0.400
ENSPFOP00000000337	ENSPFOP00000025721	ENSPFOP00000000337	ENSPFOP00000025721	Uncharacterized protein.	Death domain-containing protein.	0.400
ENSPFOP00000000337	ENSPFOP00000027647	ENSPFOP00000000337	ENSPFOP00000027647	Uncharacterized protein.	Uncharacterized protein.	0.400
ENSPFOP00000000337	LOC103150967	ENSPFOP00000000337	ENSPFOP00000027080	Uncharacterized protein.	Pleckstrin homology domain containing, family G (with RhoGef domain) member 5b.	0.400
ENSPFOP00000000337	OTULIN	ENSPFOP00000000337	ENSPFOP00000029187	Uncharacterized protein.	OTU deubiquitinase with linear linkage specificity.	0.556
ENSPFOP00000000337	rnf216	ENSPFOP00000000337	ENSPFOP00000015244	Uncharacterized protein.	Ring finger protein 216.	0.623
ENSPFOP00000000337	rnf31	ENSPFOP00000000337	ENSPFOP00000001747	Uncharacterized protein.	Ring finger protein 31.	0.623
ENSPFOP00000001741	ENSPFOP00000003085	ENSPFOP00000001741	ENSPFOP00000003085	Tumor necrosis factor receptor superfamily, member 11b.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.594
ENSPFOP00000001741	ENSPFOP00000004533	ENSPFOP00000001741	ENSPFOP00000004533	Tumor necrosis factor receptor superfamily, member 11b.	TNF superfamily member 14; Belongs to the tumor necrosis factor family.	0.822
ENSPFOP00000001741	ENSPFOP00000008496	ENSPFOP00000001741	ENSPFOP00000008496	Tumor necrosis factor receptor superfamily, member 11b.	TNFR-Cys domain-containing protein.	0.538
ENSPFOP00000001741	ENSPFOP00000008503	ENSPFOP00000001741	ENSPFOP00000008503	Tumor necrosis factor receptor superfamily, member 11b.	TNFR-Cys domain-containing protein.	0.537
ENSPFOP00000001741	ENSPFOP00000012411	ENSPFOP00000001741	ENSPFOP00000012411	Tumor necrosis factor receptor superfamily, member 11b.	Tumor necrosis factor a (TNF superfamily, member 2); Belongs to the tumor necrosis factor family.	0.762
ENSPFOP00000001741	ENSPFOP00000021860	ENSPFOP00000001741	ENSPFOP00000021860	Tumor necrosis factor receptor superfamily, member 11b.	Uncharacterized protein.	0.594
ENSPFOP00000001741	ENSPFOP00000024345	ENSPFOP00000001741	ENSPFOP00000024345	Tumor necrosis factor receptor superfamily, member 11b.	Ring finger protein 41, like.	0.594
ENSPFOP00000001741	ENSPFOP00000029105	ENSPFOP00000001741	ENSPFOP00000029105	Tumor necrosis factor receptor superfamily, member 11b.	annotation not available	0.594
ENSPFOP00000001741	LOC103136547	ENSPFOP00000001741	ENSPFOP00000014414	Tumor necrosis factor receptor superfamily, member 11b.	Tumor necrosis factor receptor superfamily, member 1B.	0.407
ENSPFOP00000001741	LOC103140155	ENSPFOP00000001741	ENSPFOP00000013508	Tumor necrosis factor receptor superfamily, member 11b.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.931