22 items (Poecilia formosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000001341	RECA_2 domain-containing protein. (301 aa)
	brca2	BRCA2 DNA repair associated. (3036 aa)
	rad51d	RAD51 paralog D. (333 aa)
	ENSPFOP00000002084	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (346 aa)
	ENSPFOP00000003275	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (722 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1312 aa)
	brca1	Uncharacterized protein. (1316 aa)
	ENSPFOP00000005078	BRCA1 associated RING domain 1. (745 aa)
	slf1	SMC5-SMC6 complex localization factor 1. (880 aa)
	ankrd11	Ankyrin repeat domain 11. (2825 aa)
	ENSPFOP00000006168	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3081 aa)
	LOC103132650	Tumor protein p53 binding protein, 1. (1538 aa)
	mcph1	Microcephalin 1. (808 aa)
	rad51c	RAD51 paralog C. (357 aa)
	chek2	Checkpoint kinase 2. (514 aa)
	ENSPFOP00000013687	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2661 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
	nbn	Nibrin. (843 aa)
	ENSPFOP00000016572	BRCA1 interacting protein C-terminal helicase 1. (1163 aa)
	topbp1	DNA topoisomerase II binding protein 1. (1515 aa)
	ENSPFOP00000023184	Uncharacterized protein. (679 aa)
	ENSPFOP00000025830	Uncharacterized protein. (2090 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000001341	ENSPFOP00000002084	ENSPFOP00000001341	ENSPFOP00000002084	RECA_2 domain-containing protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.933
ENSPFOP00000001341	ENSPFOP00000003275	ENSPFOP00000001341	ENSPFOP00000003275	RECA_2 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.835
ENSPFOP00000001341	ENSPFOP00000005078	ENSPFOP00000001341	ENSPFOP00000005078	RECA_2 domain-containing protein.	BRCA1 associated RING domain 1.	0.787
ENSPFOP00000001341	ENSPFOP00000006168	ENSPFOP00000001341	ENSPFOP00000006168	RECA_2 domain-containing protein.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.776
ENSPFOP00000001341	ENSPFOP00000016572	ENSPFOP00000001341	ENSPFOP00000016572	RECA_2 domain-containing protein.	BRCA1 interacting protein C-terminal helicase 1.	0.714
ENSPFOP00000001341	ENSPFOP00000023184	ENSPFOP00000001341	ENSPFOP00000023184	RECA_2 domain-containing protein.	Uncharacterized protein.	0.710
ENSPFOP00000001341	ankrd11	ENSPFOP00000001341	ENSPFOP00000005627	RECA_2 domain-containing protein.	Ankyrin repeat domain 11.	0.640
ENSPFOP00000001341	brca1	ENSPFOP00000001341	ENSPFOP00000004695	RECA_2 domain-containing protein.	Uncharacterized protein.	0.822
ENSPFOP00000001341	brca2	ENSPFOP00000001341	ENSPFOP00000001575	RECA_2 domain-containing protein.	BRCA2 DNA repair associated.	0.869
ENSPFOP00000001341	mcph1	ENSPFOP00000001341	ENSPFOP00000008633	RECA_2 domain-containing protein.	Microcephalin 1.	0.663
ENSPFOP00000001341	nbn	ENSPFOP00000001341	ENSPFOP00000016046	RECA_2 domain-containing protein.	Nibrin.	0.724
ENSPFOP00000001341	rad50	ENSPFOP00000001341	ENSPFOP00000003425	RECA_2 domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.725
ENSPFOP00000001341	rad51	ENSPFOP00000001341	ENSPFOP00000014345	RECA_2 domain-containing protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.958
ENSPFOP00000001341	rad51c	ENSPFOP00000001341	ENSPFOP00000011513	RECA_2 domain-containing protein.	RAD51 paralog C.	0.991
ENSPFOP00000001341	rad51d	ENSPFOP00000001341	ENSPFOP00000001922	RECA_2 domain-containing protein.	RAD51 paralog D.	0.992
ENSPFOP00000001341	slf1	ENSPFOP00000001341	ENSPFOP00000005148	RECA_2 domain-containing protein.	SMC5-SMC6 complex localization factor 1.	0.595
ENSPFOP00000002084	ENSPFOP00000001341	ENSPFOP00000002084	ENSPFOP00000001341	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	RECA_2 domain-containing protein.	0.933
ENSPFOP00000002084	ENSPFOP00000003275	ENSPFOP00000002084	ENSPFOP00000003275	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.930
ENSPFOP00000002084	ENSPFOP00000005078	ENSPFOP00000002084	ENSPFOP00000005078	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	BRCA1 associated RING domain 1.	0.896
ENSPFOP00000002084	ENSPFOP00000006168	ENSPFOP00000002084	ENSPFOP00000006168	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.885