STRINGSTRING
fgf23 fgf23 LOC103129920 LOC103129920 fgf8 fgf8 ENSPFOP00000003140 ENSPFOP00000003140 ENSPFOP00000004278 ENSPFOP00000004278 LOC103152302 LOC103152302 ENSPFOP00000006511 ENSPFOP00000006511 ENSPFOP00000006794 ENSPFOP00000006794 ENSPFOP00000008302 ENSPFOP00000008302 fgf19 fgf19 fgf5 fgf5 LOC103148401 LOC103148401
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (260 aa)
LOC103129920Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
ENSPFOP00000003140Fibroblast growth factor receptor. (814 aa)
ENSPFOP00000004278Uncharacterized protein. (981 aa)
LOC103152302Fibroblast growth factor receptor. (699 aa)
ENSPFOP00000006511Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
ENSPFOP00000006794Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
ENSPFOP00000008302Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
LOC103148401Fibroblast growth factor receptor. (831 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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