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| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (571 aa) |
| | ENSPFOP00000031067 | Uncharacterized protein. (706 aa) |
| | ENSPFOP00000030699 | Uncharacterized protein. (544 aa) |
| | ENSPFOP00000030476 | Rad21_Rec8 domain-containing protein. (313 aa) |
| | LOC107834831 | Excision repair cross-complementation group 4. (587 aa) |
| | ENSPFOP00000029322 | Uncharacterized protein. (717 aa) |
| | LOC103141893 | HD domain-containing protein. (485 aa) |
| | ENSPFOP00000028512 | Zinc finger, FYVE domain containing 26. (2593 aa) |
| | ENSPFOP00000028267 | Uncharacterized protein. (649 aa) |
| | ENSPFOP00000028108 | Uncharacterized protein. (799 aa) |
| | ENSPFOP00000028055 | Reverse transcriptase domain-containing protein. (432 aa) |
| | ENSPFOP00000027854 | HD domain-containing protein. (457 aa) |
| | ENSPFOP00000027557 | Uncharacterized protein. (587 aa) |
| | ENSPFOP00000026478 | SMC hinge domain-containing protein. (369 aa) |
| | ankle1 | Zgc:85936. (1139 aa) |
| | LOC103143686 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | ENSPFOP00000025328 | Uncharacterized protein. (190 aa) |
| | ENSPFOP00000024613 | RING-type domain-containing protein. (602 aa) |
| | LOC103141172 | Zgc:66440. (372 aa) |
| | ENSPFOP00000023960 | RING-type domain-containing protein. (839 aa) |
| | ENSPFOP00000023184 | Uncharacterized protein. (679 aa) |
| | ENSPFOP00000023165 | Excision repair cross-complementation group 8. (402 aa) |
| | LOC103132040 | DTC domain-containing protein. (172 aa) |
| | prkdc | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4119 aa) |
| | palb2 | PALB2_WD40 domain-containing protein. (1340 aa) |
| | ENSPFOP00000022612 | Uncharacterized protein. (322 aa) |
| | ENSPFOP00000021839 | Si:ch211-241j8.2. (475 aa) |
| | ENSPFOP00000021397 | Reverse transcriptase domain-containing protein. (784 aa) |
| | ENSPFOP00000021304 | Uncharacterized protein. (544 aa) |
| | ENSPFOP00000020763 | BRCA1/BRCA2-containing complex, subunit 3. (266 aa) |
| | LOC103149460 | Nipped-B protein. (2843 aa) |
| | ENSPFOP00000019815 | SWI5 homologous recombination repair protein. (131 aa) |
| | ENSPFOP00000019748 | Polymerase (DNA directed), theta. (2486 aa) |
| | mfsd11 | Major facilitator superfamily domain containing 11. (454 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (311 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (462 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1231 aa) |
| | LOC103144707 | ERCC4 domain-containing protein. (518 aa) |
| | smarcad1 | Uncharacterized protein. (1090 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (514 aa) |
| | ENSPFOP00000018931 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (642 aa) |
| | polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (439 aa) |
| | ENSPFOP00000018819 | Zinc finger, SWIM-type containing 7. (132 aa) |
| | nipbl | Nipped-B protein. (2354 aa) |
| | ercc1 | Excision repair cross-complementation group 1. (356 aa) |
| | LOC103135049 | RAD21 cohesin complex component a. (637 aa) |
| | ENSPFOP00000018079 | Nonhomologous end-joining factor 1. (309 aa) |
| | LOC103154119 | Endo/exonuclease/phosphatase domain-containing protein. (278 aa) |
| | ENSPFOP00000018038 | Tyrosyl-DNA phosphodiesterase 1. (645 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (424 aa) |
| | ENSPFOP00000017313 | X-ray repair complementing defective repair in Chinese hamster cells 4. (343 aa) |
| | ENSPFOP00000017301 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1940 aa) |
| | ENSPFOP00000017291 | Cell division cycle 7 homolog (S. cerevisiae); Belongs to the protein kinase superfamily. (484 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa) |
| | LOC103137800 | Histone PARylation factor 1. (352 aa) |
| | vcp | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | ENSPFOP00000016559 | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (603 aa) |
| | ENSPFOP00000016420 | Uncharacterized protein. (940 aa) |
| | LOC103138163 | Nucleic acid binding protein 1a. (221 aa) |
| | LOC103138161 | Nucleic acid binding protein 1a. (221 aa) |
| | psmd14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | LOC103132374 | HD domain-containing protein. (463 aa) |
| | nbn | Nibrin. (843 aa) |
| | sfr1 | SWI5-dependent homologous recombination repair protein 1. (204 aa) |
| | ENSPFOP00000015650 | WD repeat domain 48b. (682 aa) |
| | EME2 | ERCC4 domain-containing protein. (435 aa) |
| | ENSPFOP00000015340 | Uncharacterized protein. (1194 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (954 aa) |
| | LOC103151399 | Uncharacterized protein. (890 aa) |
| | ENSPFOP00000014766 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (977 aa) |
| | ENSPFOP00000014718 | UV radiation resistance associated gene. (700 aa) |
| | ENSPFOP00000014560 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1952 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (827 aa) |
| | ENSPFOP00000014489 | Uncharacterized protein. (827 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (868 aa) |
| | LOC103138354 | DNA helicase; Belongs to the MCM family. (825 aa) |
| | ENSPFOP00000014359 | Methionine sulfoxide reductase B1b. (471 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | LOC103148896 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (264 aa) |
| | smc5 | Structural maintenance of chromosomes 5. (1073 aa) |
| | ENSPFOP00000013916 | Tonsoku-like, DNA repair protein. (1372 aa) |
| | ENSPFOP00000013752 | Tyrosyl-DNA phosphodiesterase 2b. (363 aa) |
| | ENSPFOP00000013633 | Intermediate filament family orphan 1b; Belongs to the intermediate filament family. (620 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (863 aa) |
| | ENSPFOP00000013503 | INO80 complex ATPase subunit. (1568 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (729 aa) |
| | ENSPFOP00000013259 | Intermediate filament family orphan 2b; Belongs to the intermediate filament family. (479 aa) |
| | rfwd3 | Ring finger and WD repeat domain 3. (716 aa) |
| | sirt6 | Sirtuin 6. (390 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa) |
| | polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (338 aa) |
| | ENSPFOP00000012327 | RING-type domain-containing protein. (193 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (591 aa) |
| | ddx1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa) |
| | rmi2 | RecQ mediated genome instability 2. (146 aa) |
| | LOC103143791 | Uncharacterized protein. (446 aa) |
| | chek2 | Checkpoint kinase 2. (514 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (886 aa) |
| | MARF1 | Meiosis regulator and mRNA stability factor 1. (1792 aa) |
| | rad51c | RAD51 paralog C. (357 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (382 aa) |
| | ENSPFOP00000011039 | Uncharacterized protein. (333 aa) |
| | ENSPFOP00000011005 | BRISC and BRCA1 A complex member 2. (331 aa) |
| | rnf169 | Ring finger protein 169. (574 aa) |
| | ap5s1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (937 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (390 aa) |
| | LOC103146448 | Intermediate filament family orphan 1a; Belongs to the intermediate filament family. (628 aa) |
| | LOC103141874 | SAM domain and HD domain 1. (627 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (635 aa) |
| | pnkp | Polynucleotide kinase 3'-phosphatase. (593 aa) |
| | actr5 | Actin related protein 5; Belongs to the actin family. (620 aa) |
| | LOC103132650 | Tumor protein p53 binding protein, 1. (1538 aa) |
| | ENSPFOP00000007857 | Si:dkey-117m1.4. (688 aa) |
| | ENSPFOP00000007332 | Polymerase (DNA directed) nu. (657 aa) |
| | ENSPFOP00000007060 | Si:cabz01080528.1. (901 aa) |
| | ENSPFOP00000006892 | Uncharacterized protein. (643 aa) |
| | nsmce1 | NSE1 homolog, SMC5-SMC6 complex component. (247 aa) |
| | ercc6 | Excision repair cross-complementation group 6. (1449 aa) |
| | recql5 | RecQ helicase-like 5. (1012 aa) |
| | LOC103152896 | Essential meiotic structure-specific endonuclease 1. (519 aa) |
| | rnf168 | Ring finger protein 168. (431 aa) |
| | ENSPFOP00000006168 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3081 aa) |
| | LOC103147317 | SET domain and mariner transposase fusion gene. (283 aa) |
| | fbh1 | F-box DNA helicase 1. (1057 aa) |
| | recql4 | RecQ helicase-like 4. (1494 aa) |
| | ENSPFOP00000005619 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa) |
| | ENSPFOP00000005317 | RING-type domain-containing protein. (217 aa) |
| | blm | BLM RecQ like helicase. (1366 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (573 aa) |
| | ENSPFOP00000005090 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1444 aa) |
| | ENSPFOP00000004888 | SEM1 26S proteasome complex subunit. (71 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (944 aa) |
| | brca1 | Uncharacterized protein. (1316 aa) |
| | ENSPFOP00000004552 | RAD21 cohesin complex component like 1. (636 aa) |
| | ap5z1 | Adaptor related protein complex 5 subunit zeta 1. (802 aa) |
| | LOC103154164 | Zgc:136908; Belongs to the AAA ATPase family. (810 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (683 aa) |
| | fancd2 | FA complementation group D2. (1436 aa) |
| | ENSPFOP00000004237 | Excision repair cross-complementation group 4. (761 aa) |
| | ENSPFOP00000004202 | X-ray repair complementing defective repair in Chinese hamster cells 4. (322 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | LOC103154570 | RAD21 cohesin complex component. (646 aa) |
| | parp2 | Poly [ADP-ribose] polymerase. (650 aa) |
| | pola1 | DNA polymerase. (1478 aa) |
| | ENSPFOP00000003432 | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (364 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | ENSPFOP00000003275 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (722 aa) |
| | ENSPFOP00000003274 | SWIM-type zinc finger 7 associated protein 1. (245 aa) |
| | LOC103134226 | FA complementation group B. (842 aa) |
| | ENSPFOP00000003063 | REV3 like, DNA directed polymerase zeta catalytic subunit. (2861 aa) |
| | dclre1a | DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (895 aa) |
| | parp3 | Poly [ADP-ribose] polymerase. (522 aa) |
| | ENSPFOP00000002611 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa) |
| | prpf19 | Pre-mRNA processing factor 19. (505 aa) |
| | ENSPFOP00000002397 | DNA ligase. (924 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa) |
| | ENSPFOP00000002331 | Abraxas 1, BRCA1 A complex subunit. (350 aa) |
| | ENSPFOP00000002183 | Helicase, POLQ like. (998 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | ENSPFOP00000002114 | Helicase C-terminal domain-containing protein. (1463 aa) |
| | ENSPFOP00000002084 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (346 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | ENSPFOP00000001674 | Cell division cycle associated 5. (248 aa) |
| | brca2 | BRCA2 DNA repair associated. (3036 aa) |
| | ENSPFOP00000001341 | RECA_2 domain-containing protein. (301 aa) |
| | dclre1b | DNA cross-link repair 1B. (569 aa) |
| | ENSPFOP00000001035 | RING-type domain-containing protein. (340 aa) |
| | LOC103133080 | Uncharacterized protein. (206 aa) |
| | recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (655 aa) |
| | lig4 | DNA ligase. (908 aa) |
| | ENSPFOP00000000434 | Heat shock transcription factor 2 binding protein. (324 aa) |
| | LOC103154963 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (585 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (722 aa) |
| | paxx | Uncharacterized protein. (184 aa) |
| | ENSPFOP00000000148 | Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (424 aa) |
| | DNTT | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (473 aa) |
