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ENSPFOP00000007549 ENSPFOP00000007549 dhcr24 dhcr24 prkaa2 prkaa2 prkaa1 prkaa1 insig1 insig1 fdps fdps idi1 idi1 lss lss nsdhl nsdhl LOC103135855 LOC103135855 pmvk pmvk sc5d sc5d ENSPFOP00000007177 ENSPFOP00000007177 ENSPFOP00000007132 ENSPFOP00000007132 fdft1 fdft1 LOC103132185 LOC103132185 hmgcs1 hmgcs1 ebp ebp mvd mvd tm7sf2 tm7sf2 insig2 insig2 ENSPFOP00000021252 ENSPFOP00000021252 HSD17B7 HSD17B7 ENSPFOP00000025013 ENSPFOP00000025013 ENSPFOP00000025881 ENSPFOP00000025881
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPFOP00000007549Hydroxysteroid (17-beta) dehydrogenase 7. (357 aa)
dhcr2424-dehydrocholesterol reductase. (517 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (275 aa)
fdpsUncharacterized protein; Belongs to the FPP/GGPP synthase family. (358 aa)
idi1Isopentenyl-diphosphate delta isomerase 1. (286 aa)
lssTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (735 aa)
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (345 aa)
LOC1031358553-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
pmvkPhosphomevalonate kinase. (264 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (292 aa)
ENSPFOP000000071777-dehydrocholesterol reductase. (478 aa)
ENSPFOP00000007132Cytochrome P450, family 51; Belongs to the cytochrome P450 family. (497 aa)
fdft1Farnesyl-diphosphate farnesyltransferase 1. (417 aa)
LOC1031321853-hydroxy-3-methylglutaryl coenzyme A reductase. (873 aa)
hmgcs13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (519 aa)
ebpEBP cholestenol delta-isomerase. (229 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (404 aa)
tm7sf2Transmembrane 7 superfamily member 2. (445 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (235 aa)
ENSPFOP000000212523-hydroxy-3-methylglutaryl coenzyme A reductase. (815 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (345 aa)
ENSPFOP00000025013Uncharacterized protein. (1837 aa)
ENSPFOP00000025881Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (380 aa)
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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