node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103141173 | ptges3 | ENSPFOP00000012432 | ENSPFOP00000011954 | Prostaglandin E synthase 3a (cytosolic). | Prostaglandin E synthase 3b (cytosolic). | 0.905 |
LOC103141173 | tert | ENSPFOP00000012432 | ENSPFOP00000015052 | Prostaglandin E synthase 3a (cytosolic). | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.712 |
LOC103156947 | dkc1 | ENSPFOP00000002381 | ENSPFOP00000018771 | Uncharacterized protein. | Dyskeratosis congenita 1, dyskerin. | 0.673 |
LOC103156947 | gar1 | ENSPFOP00000002381 | ENSPFOP00000025778 | Uncharacterized protein. | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | 0.646 |
LOC103156947 | nhp2 | ENSPFOP00000002381 | ENSPFOP00000002190 | Uncharacterized protein. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.673 |
LOC103156947 | nop10 | ENSPFOP00000002381 | ENSPFOP00000002438 | Uncharacterized protein. | NOP10 ribonucleoprotein homolog (yeast). | 0.674 |
LOC103156947 | pot1 | ENSPFOP00000002381 | ENSPFOP00000017027 | Uncharacterized protein. | Telo_bind domain-containing protein. | 0.995 |
LOC103156947 | tert | ENSPFOP00000002381 | ENSPFOP00000015052 | Uncharacterized protein. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.960 |
LOC103156947 | wrap53 | ENSPFOP00000002381 | ENSPFOP00000008839 | Uncharacterized protein. | WD repeat containing, antisense to TP53. | 0.653 |
RPA1 | pot1 | ENSPFOP00000012296 | ENSPFOP00000017027 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Telo_bind domain-containing protein. | 0.658 |
RPA1 | rad50 | ENSPFOP00000012296 | ENSPFOP00000003425 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | RAD50 homolog, double strand break repair protein. | 0.857 |
RPA1 | rpa1 | ENSPFOP00000012296 | ENSPFOP00000004158 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.905 |
RPA1 | tert | ENSPFOP00000012296 | ENSPFOP00000015052 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.839 |
dkc1 | LOC103156947 | ENSPFOP00000018771 | ENSPFOP00000002381 | Dyskeratosis congenita 1, dyskerin. | Uncharacterized protein. | 0.673 |
dkc1 | gar1 | ENSPFOP00000018771 | ENSPFOP00000025778 | Dyskeratosis congenita 1, dyskerin. | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. | 0.999 |
dkc1 | nhp2 | ENSPFOP00000018771 | ENSPFOP00000002190 | Dyskeratosis congenita 1, dyskerin. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.999 |
dkc1 | nop10 | ENSPFOP00000018771 | ENSPFOP00000002438 | Dyskeratosis congenita 1, dyskerin. | NOP10 ribonucleoprotein homolog (yeast). | 0.999 |
dkc1 | pinx1 | ENSPFOP00000018771 | ENSPFOP00000009977 | Dyskeratosis congenita 1, dyskerin. | PIN2 (TERF1) interacting telomerase inhibitor 1. | 0.490 |
dkc1 | pot1 | ENSPFOP00000018771 | ENSPFOP00000017027 | Dyskeratosis congenita 1, dyskerin. | Telo_bind domain-containing protein. | 0.729 |
dkc1 | tert | ENSPFOP00000018771 | ENSPFOP00000015052 | Dyskeratosis congenita 1, dyskerin. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.969 |