(13 nodes) Multicellular organism aging network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103153585	Amino acid transporter. (538 aa)
	rnf165	Ring finger protein 165a. (346 aa)
	ENSPFOP00000027974	Uncharacterized protein. (387 aa)
	slc1a2	Amino acid transporter. (537 aa)
	LOC103149245	Guanine nucleotide binding protein (G protein), alpha 13b. (385 aa)
	ENSPFOP00000018268	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	sec63	SEC63 homolog, protein translocation regulator. (761 aa)
	LOC103144939	Amino acid transporter. (675 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (444 aa)
	ENSPFOP00000006756	Ring finger protein 165b. (305 aa)
	edn1	Endothelin 1. (187 aa)
	LOC103151262	Uncharacterized protein. (377 aa)
	ercc1	Excision repair cross-complementation group 1. (356 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000018268	ENSPFOP00000027974	ENSPFOP00000018268	ENSPFOP00000027974	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.933
ENSPFOP00000018268	LOC103149245	ENSPFOP00000018268	ENSPFOP00000015112	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.936
ENSPFOP00000018268	LOC103151262	ENSPFOP00000018268	ENSPFOP00000014197	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.933
ENSPFOP00000018268	edn1	ENSPFOP00000018268	ENSPFOP00000005291	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.993
ENSPFOP00000018268	ednra	ENSPFOP00000018268	ENSPFOP00000008961	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.901
ENSPFOP00000027974	ENSPFOP00000018268	ENSPFOP00000027974	ENSPFOP00000018268	Uncharacterized protein.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.933
ENSPFOP00000027974	LOC103149245	ENSPFOP00000027974	ENSPFOP00000015112	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.924
ENSPFOP00000027974	LOC103151262	ENSPFOP00000027974	ENSPFOP00000014197	Uncharacterized protein.	Uncharacterized protein.	0.924
ENSPFOP00000027974	ednra	ENSPFOP00000027974	ENSPFOP00000008961	Uncharacterized protein.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.948
LOC103149245	ENSPFOP00000018268	ENSPFOP00000015112	ENSPFOP00000018268	Guanine nucleotide binding protein (G protein), alpha 13b.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.936
LOC103149245	ENSPFOP00000027974	ENSPFOP00000015112	ENSPFOP00000027974	Guanine nucleotide binding protein (G protein), alpha 13b.	Uncharacterized protein.	0.924
LOC103149245	LOC103151262	ENSPFOP00000015112	ENSPFOP00000014197	Guanine nucleotide binding protein (G protein), alpha 13b.	Uncharacterized protein.	0.952
LOC103149245	ednra	ENSPFOP00000015112	ENSPFOP00000008961	Guanine nucleotide binding protein (G protein), alpha 13b.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.968
LOC103151262	ENSPFOP00000018268	ENSPFOP00000014197	ENSPFOP00000018268	Uncharacterized protein.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.933
LOC103151262	ENSPFOP00000027974	ENSPFOP00000014197	ENSPFOP00000027974	Uncharacterized protein.	Uncharacterized protein.	0.924
LOC103151262	LOC103149245	ENSPFOP00000014197	ENSPFOP00000015112	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.952
LOC103151262	ednra	ENSPFOP00000014197	ENSPFOP00000008961	Uncharacterized protein.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.968
edn1	ENSPFOP00000018268	ENSPFOP00000005291	ENSPFOP00000018268	Endothelin 1.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.993
edn1	ednra	ENSPFOP00000005291	ENSPFOP00000008961	Endothelin 1.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.997
ednra	ENSPFOP00000018268	ENSPFOP00000008961	ENSPFOP00000018268	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.901