(36 nodes) Inclusion body network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000010558	Si:ch211-263k4.2. (1167 aa)
	ENSPFOP00000000002	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (420 aa)
	nup98	Nucleoporin 98. (1820 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (117 aa)
	LOC103152278	Ataxin 1b. (825 aa)
	LOC103156371	Kelch-like ECH-associated protein 1a. (600 aa)
	rad18	RAD18 E3 ubiquitin protein ligase. (493 aa)
	xrn2	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (967 aa)
	slf1	SMC5-SMC6 complex localization factor 1. (880 aa)
	ENSPFOP00000005486	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (440 aa)
	tpr	Translocated promoter region a, nuclear basket protein. (2481 aa)
	bag5	BCL2 associated athanogene 5. (485 aa)
	ranbp2	RAN binding protein 2. (3082 aa)
	pold1	DNA polymerase. (1109 aa)
	ENSPFOP00000008040	Tripartite motif containing 66. (1188 aa)
	zbtb14	Zinc finger and BTB domain containing 14. (435 aa)
	LOC103147783	AXH domain-containing protein. (675 aa)
	ENSPFOP00000010740	WD repeat and FYVE domain containing 3. (1901 aa)
	ENSPFOP00000011880	Leucine-rich repeat kinase 2. (1882 aa)
	ENSPFOP00000013288	Nucleoporin 153. (1456 aa)
	keap1	Kelch-like ECH-associated protein 1b. (615 aa)
	LOC103137288	Translocated promoter region b, nuclear basket protein. (2358 aa)
	rangap1	RAN GTPase activating protein 1a. (578 aa)
	atxn1	Ataxin 1a. (799 aa)
	ENSPFOP00000014648	Kelch-like family member 14. (606 aa)
	hspb7	Heat shock protein family, member 7 (cardiovascular); Belongs to the small heat shock protein (HSP20) family. (156 aa)
	fbxo7	F-box protein 7. (464 aa)
	ENSPFOP00000016480	Caspase recruitment domain family, member 14. (947 aa)
	LOC103143341	Ran GTPase activating protein 1b. (564 aa)
	sqstm1	Sequestosome 1. (463 aa)
	LOC103146330	Uncharacterized protein. (391 aa)
	ENSPFOP00000020798	Si:ch211-263k4.2. (134 aa)
	ENSPFOP00000025335	AXH domain-containing protein. (207 aa)
	ENSPFOP00000026124	Uncharacterized protein. (76 aa)
	ENSPFOP00000028505	Bromo domain-containing protein. (202 aa)
	ENSPFOP00000029352	Tripartite motif containing 37. (793 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000005486	ENSPFOP00000011880	ENSPFOP00000005486	ENSPFOP00000011880	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Leucine-rich repeat kinase 2.	0.627
ENSPFOP00000005486	bag5	ENSPFOP00000005486	ENSPFOP00000007198	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	BCL2 associated athanogene 5.	0.578
ENSPFOP00000005486	fbxo7	ENSPFOP00000005486	ENSPFOP00000015565	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	F-box protein 7.	0.672
ENSPFOP00000005486	ranbp2	ENSPFOP00000005486	ENSPFOP00000007571	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	RAN binding protein 2.	0.550
ENSPFOP00000005486	slf1	ENSPFOP00000005486	ENSPFOP00000005148	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	SMC5-SMC6 complex localization factor 1.	0.590
ENSPFOP00000005486	sqstm1	ENSPFOP00000005486	ENSPFOP00000017211	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Sequestosome 1.	0.953
ENSPFOP00000010558	ENSPFOP00000020798	ENSPFOP00000010558	ENSPFOP00000020798	Si:ch211-263k4.2.	Si:ch211-263k4.2.	0.845
ENSPFOP00000010740	sqstm1	ENSPFOP00000010740	ENSPFOP00000017211	WD repeat and FYVE domain containing 3.	Sequestosome 1.	0.828
ENSPFOP00000011880	ENSPFOP00000005486	ENSPFOP00000011880	ENSPFOP00000005486	Leucine-rich repeat kinase 2.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.627
ENSPFOP00000011880	bag5	ENSPFOP00000011880	ENSPFOP00000007198	Leucine-rich repeat kinase 2.	BCL2 associated athanogene 5.	0.680
ENSPFOP00000013288	LOC103137288	ENSPFOP00000013288	ENSPFOP00000014127	Nucleoporin 153.	Translocated promoter region b, nuclear basket protein.	0.946
ENSPFOP00000013288	LOC103143341	ENSPFOP00000013288	ENSPFOP00000017011	Nucleoporin 153.	Ran GTPase activating protein 1b.	0.837
ENSPFOP00000013288	nup98	ENSPFOP00000013288	ENSPFOP00000000406	Nucleoporin 153.	Nucleoporin 98.	0.990
ENSPFOP00000013288	ranbp2	ENSPFOP00000013288	ENSPFOP00000007571	Nucleoporin 153.	RAN binding protein 2.	0.999
ENSPFOP00000013288	rangap1	ENSPFOP00000013288	ENSPFOP00000014314	Nucleoporin 153.	RAN GTPase activating protein 1a.	0.837
ENSPFOP00000013288	tpr	ENSPFOP00000013288	ENSPFOP00000006667	Nucleoporin 153.	Translocated promoter region a, nuclear basket protein.	0.946
ENSPFOP00000014648	sqstm1	ENSPFOP00000014648	ENSPFOP00000017211	Kelch-like family member 14.	Sequestosome 1.	0.462
ENSPFOP00000020798	ENSPFOP00000010558	ENSPFOP00000020798	ENSPFOP00000010558	Si:ch211-263k4.2.	Si:ch211-263k4.2.	0.845
ENSPFOP00000026124	ENSPFOP00000029352	ENSPFOP00000026124	ENSPFOP00000029352	Uncharacterized protein.	Tripartite motif containing 37.	0.919
ENSPFOP00000029352	ENSPFOP00000026124	ENSPFOP00000029352	ENSPFOP00000026124	Tripartite motif containing 37.	Uncharacterized protein.	0.919