(21 nodes) Lateral plasma membrane network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000012222	KCNQ_channel domain-containing protein. (105 aa)
	LOC103140783	Uncharacterized protein. (200 aa)
	LOC103149554	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (184 aa)
	ENSPFOP00000019403	Uncharacterized protein; Belongs to the potassium channel family. (538 aa)
	LOC103133959	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (254 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	NSG1	Neuronal vesicle trafficking associated 1. (185 aa)
	tbcd	Tubulin folding cofactor D. (1201 aa)
	slc26a5	Solute carrier family 26 member 5. (732 aa)
	ENSPFOP00000001607	Microtubule crosslinking factor 1. (476 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	ENSPFOP00000001058	Basigin. (273 aa)
	ENSPFOP00000024361	Ion_trans domain-containing protein; Belongs to the potassium channel family. (580 aa)
	LOC103156152	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	LOC103129310	Ion_trans domain-containing protein; Belongs to the potassium channel family. (467 aa)
	ENSPFOP00000007079	Blood vessel epicardial substance. (349 aa)
	ENSPFOP00000008393	Uncharacterized protein. (2069 aa)
	ENSPFOP00000027731	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (254 aa)
	c1qtnf5	C1q and TNF related 5. (250 aa)
	ENSPFOP00000010376	Uncharacterized protein. (1116 aa)
	akap7	Uncharacterized protein. (506 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000012222	LOC103129310	ENSPFOP00000012222	ENSPFOP00000000219	KCNQ_channel domain-containing protein.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.641
ENSPFOP00000019403	ENSPFOP00000024361	ENSPFOP00000019403	ENSPFOP00000024361	Uncharacterized protein; Belongs to the potassium channel family.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.866
ENSPFOP00000024361	ENSPFOP00000019403	ENSPFOP00000024361	ENSPFOP00000019403	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Uncharacterized protein; Belongs to the potassium channel family.	0.866
ENSPFOP00000024361	LOC103129310	ENSPFOP00000024361	ENSPFOP00000000219	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.864
ENSPFOP00000027731	LOC103149554	ENSPFOP00000027731	ENSPFOP00000016710	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.550
LOC103129310	ENSPFOP00000012222	ENSPFOP00000000219	ENSPFOP00000012222	Ion_trans domain-containing protein; Belongs to the potassium channel family.	KCNQ_channel domain-containing protein.	0.641
LOC103129310	ENSPFOP00000024361	ENSPFOP00000000219	ENSPFOP00000024361	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.864
LOC103133959	LOC103149554	ENSPFOP00000019518	ENSPFOP00000016710	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.462
LOC103149554	ENSPFOP00000027731	ENSPFOP00000016710	ENSPFOP00000027731	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.550
LOC103149554	LOC103133959	ENSPFOP00000016710	ENSPFOP00000019518	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.462
LOC103149554	LOC103156152	ENSPFOP00000016710	ENSPFOP00000020908	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.909
LOC103149554	cldn5	ENSPFOP00000016710	ENSPFOP00000020589	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.904
LOC103156152	LOC103149554	ENSPFOP00000020908	ENSPFOP00000016710	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.909
LOC103156152	cldn5	ENSPFOP00000020908	ENSPFOP00000020589	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.893
arl2	tbcd	ENSPFOP00000001564	ENSPFOP00000004391	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.	Tubulin folding cofactor D.	0.976
cldn5	LOC103149554	ENSPFOP00000020589	ENSPFOP00000016710	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.904
cldn5	LOC103156152	ENSPFOP00000020589	ENSPFOP00000020908	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.893
tbcd	arl2	ENSPFOP00000004391	ENSPFOP00000001564	Tubulin folding cofactor D.	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.	0.976