(18 nodes) Protein autoprocessing network (Poecilia formosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPFOP00000022613	Tantalus domain-containing protein. (175 aa)
	sprtn	SprT-like N-terminal domain. (547 aa)
	fxn	Frataxin. (213 aa)
	dhh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (446 aa)
	LOC103156544	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (434 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (766 aa)
	myrf	Myelin regulatory factor. (1025 aa)
	ENSPFOP00000011297	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (289 aa)
	myrfl	Myelin regulatory factor like. (965 aa)
	pidd1	P53-induced death domain protein 1. (940 aa)
	PISD	Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (370 aa)
	pcsk2	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (644 aa)
	LOC103137064	OMA1 zinc metallopeptidase. (508 aa)
	LOC103140457	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	pcsk9	Uncharacterized protein. (499 aa)
	ihh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa)
	ENSPFOP00000023625	Peptidase_S8 domain-containing protein. (131 aa)
	LOC103156544-2	Indian hedgehog B protein-like. (434 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000011297	pidd1	ENSPFOP00000011297	ENSPFOP00000011876	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	P53-induced death domain protein 1.	0.743
ENSPFOP00000022613	pidd1	ENSPFOP00000022613	ENSPFOP00000011876	Tantalus domain-containing protein.	P53-induced death domain protein 1.	0.452
ENSPFOP00000023625	pidd1	ENSPFOP00000023625	ENSPFOP00000011876	Peptidase_S8 domain-containing protein.	P53-induced death domain protein 1.	0.416
LOC103140457	LOC103156544	ENSPFOP00000015525	ENSPFOP00000009340	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.834
LOC103140457	LOC103156544-2	ENSPFOP00000015525	ENSPFOP00000027893	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Indian hedgehog B protein-like.	0.834
LOC103140457	dhh	ENSPFOP00000015525	ENSPFOP00000006899	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.883
LOC103140457	ihh	ENSPFOP00000015525	ENSPFOP00000018087	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.649
LOC103156544	LOC103140457	ENSPFOP00000009340	ENSPFOP00000015525	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.834
LOC103156544	dhh	ENSPFOP00000009340	ENSPFOP00000006899	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.873
LOC103156544-2	LOC103140457	ENSPFOP00000027893	ENSPFOP00000015525	Indian hedgehog B protein-like.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.834
LOC103156544-2	dhh	ENSPFOP00000027893	ENSPFOP00000006899	Indian hedgehog B protein-like.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.873
PISD	pcsk9	ENSPFOP00000013693	ENSPFOP00000016094	Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.	Uncharacterized protein.	0.480
PISD	pidd1	ENSPFOP00000013693	ENSPFOP00000011876	Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.	P53-induced death domain protein 1.	0.449
dhh	LOC103140457	ENSPFOP00000006899	ENSPFOP00000015525	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.883
dhh	LOC103156544	ENSPFOP00000006899	ENSPFOP00000009340	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.873
dhh	LOC103156544-2	ENSPFOP00000006899	ENSPFOP00000027893	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Indian hedgehog B protein-like.	0.873
dhh	ihh	ENSPFOP00000006899	ENSPFOP00000018087	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.632
ihh	LOC103140457	ENSPFOP00000018087	ENSPFOP00000015525	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.649
ihh	dhh	ENSPFOP00000018087	ENSPFOP00000006899	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.632
pcsk1	pidd1	ENSPFOP00000010482	ENSPFOP00000011876	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	P53-induced death domain protein 1.	0.416