(12 nodes) Peptidyl-proline hydroxylation to 4-hydroxy-L-proline network (Poecilia formosa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	p4ha2	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2. (536 aa)
	LOC103140905	Zgc:103625. (205 aa)
	LOC103147080	Prolyl 4-hydroxylase, alpha polypeptide I a. (541 aa)
	ENSPFOP00000006392	Methyltransferase like 26. (254 aa)
	p4ha3	Prolyl 4-hydroxylase, alpha polypeptide III. (543 aa)
	LOC103136266	Egl-9 family hypoxia-inducible factor 2. (528 aa)
	ENSPFOP00000010873	Egl-9 family hypoxia-inducible factor 3. (248 aa)
	p4htm	Prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum). (497 aa)
	p4ha1	Prolyl 4-hydroxylase, alpha polypeptide I b. (548 aa)
	prdx4	Peroxiredoxin 4. (261 aa)
	ENSPFOP00000019460	Egl-9 family hypoxia-inducible factor 1a. (357 aa)
	LOC103141882	Zgc:158254. (506 aa)

Your Current Organism:

Poecilia formosa

NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPFOP00000010873	p4ha1	ENSPFOP00000010873	ENSPFOP00000018699	Egl-9 family hypoxia-inducible factor 3.	Prolyl 4-hydroxylase, alpha polypeptide I b.	0.501
LOC103147080	p4ha1	ENSPFOP00000005774	ENSPFOP00000018699	Prolyl 4-hydroxylase, alpha polypeptide I a.	Prolyl 4-hydroxylase, alpha polypeptide I b.	0.897
LOC103147080	p4ha2	ENSPFOP00000005774	ENSPFOP00000010166	Prolyl 4-hydroxylase, alpha polypeptide I a.	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.	0.882
LOC103147080	p4ha3	ENSPFOP00000005774	ENSPFOP00000007676	Prolyl 4-hydroxylase, alpha polypeptide I a.	Prolyl 4-hydroxylase, alpha polypeptide III.	0.692
p4ha1	ENSPFOP00000010873	ENSPFOP00000018699	ENSPFOP00000010873	Prolyl 4-hydroxylase, alpha polypeptide I b.	Egl-9 family hypoxia-inducible factor 3.	0.501
p4ha1	LOC103147080	ENSPFOP00000018699	ENSPFOP00000005774	Prolyl 4-hydroxylase, alpha polypeptide I b.	Prolyl 4-hydroxylase, alpha polypeptide I a.	0.897
p4ha1	p4ha2	ENSPFOP00000018699	ENSPFOP00000010166	Prolyl 4-hydroxylase, alpha polypeptide I b.	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.	0.881
p4ha1	p4ha3	ENSPFOP00000018699	ENSPFOP00000007676	Prolyl 4-hydroxylase, alpha polypeptide I b.	Prolyl 4-hydroxylase, alpha polypeptide III.	0.692
p4ha2	LOC103147080	ENSPFOP00000010166	ENSPFOP00000005774	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.	Prolyl 4-hydroxylase, alpha polypeptide I a.	0.882
p4ha2	p4ha1	ENSPFOP00000010166	ENSPFOP00000018699	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.	Prolyl 4-hydroxylase, alpha polypeptide I b.	0.881
p4ha2	p4ha3	ENSPFOP00000010166	ENSPFOP00000007676	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.	Prolyl 4-hydroxylase, alpha polypeptide III.	0.759
p4ha3	LOC103147080	ENSPFOP00000007676	ENSPFOP00000005774	Prolyl 4-hydroxylase, alpha polypeptide III.	Prolyl 4-hydroxylase, alpha polypeptide I a.	0.692
p4ha3	p4ha1	ENSPFOP00000007676	ENSPFOP00000018699	Prolyl 4-hydroxylase, alpha polypeptide III.	Prolyl 4-hydroxylase, alpha polypeptide I b.	0.692
p4ha3	p4ha2	ENSPFOP00000007676	ENSPFOP00000010166	Prolyl 4-hydroxylase, alpha polypeptide III.	Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.	0.759